scholarly article | Q13442814 |
P356 | DOI | 10.1158/1535-7163.MCT-08-0298 |
P698 | PubMed publication ID | 18723479 |
P2093 | author name string | John Bertin | |
Mei Zhang | |||
James Barsoum | |||
Suqin He | |||
Zhenjian Du | |||
Vishwasenani Balasubramanyam | |||
Jessica R Kirshner | |||
Chin-Yu Yang | |||
Jane Kepros | |||
P2860 | cites work | Cell transformation by the superoxide-generating oxidase Mox1 | Q22010372 |
P433 | issue | 8 | |
P921 | main subject | elesclomol | Q5359460 |
apoptotic process | Q14599311 | ||
P304 | page(s) | 2319-2327 | |
P577 | publication date | 2008-08-01 | |
P1433 | published in | Molecular Cancer Therapeutics | Q2363144 |
P1476 | title | Elesclomol induces cancer cell apoptosis through oxidative stress | |
P478 | volume | 7 |
Q34884279 | 4-Methylcatechol-induced oxidative stress induces intrinsic apoptotic pathway in metastatic melanoma cells |
Q33747092 | A Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer Cells |
Q58115287 | A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation |
Q37379680 | ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. |
Q38429249 | Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death |
Q24655984 | Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1 |
Q34543548 | Autophagy: In the cROSshairs of cancer |
Q37628003 | Bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine photodynamic therapy disrupts redox homeostasis and induce mitochondria-mediated apoptosis in human breast cancer cells |
Q26772300 | Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and Radiotherapy |
Q39522763 | Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells |
Q39478541 | Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance? |
Q57801718 | Copper signalling: causes and consequences |
Q39737530 | Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism |
Q37718423 | Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition |
Q46256497 | Cytotoxicity, Oxidative Stress, Cell Cycle Arrest, and Mitochondrial Apoptosis after Combined Treatment of Hepatocarcinoma Cells with Maleic Anhydride Derivatives and Quercetin. |
Q64068568 | EF24 Suppresses Cholangiocellular Carcinoma Progression, Inhibits STAT3 Phosphorylation, and Induces Apoptosis via ROS-Mediated Oxidative Stress |
Q62390804 | Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe |
Q38747870 | Evaluation of the radiosensitizing potency of chemotherapeutic agents in prostate cancer cells |
Q52769129 | Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate. |
Q38968421 | Highly cytotoxic DNA-interacting copper(II) coordination compounds |
Q33853785 | Impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative. |
Q34466148 | Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells. |
Q37112504 | Jaridonin, a novel ent-kaurene diterpenoid from Isodon rubescens, inducing apoptosis via production of reactive oxygen species in esophageal cancer cells |
Q85174078 | LC–MS/MS and density functional theory study of copper(II) and nickel(II) chelating complexes of elesclomol (a novel anticancer agent) |
Q38943759 | Low fucose containing bacterial polysaccharide facilitate mitochondria-dependent ROS-induced apoptosis of human lung epithelial carcinoma via controlled regulation of MAPKs-mediated Nrf2/Keap1 homeostasis signaling. |
Q34505905 | Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells. |
Q90642651 | Metabolic Plasticity in Chemotherapy Resistance |
Q28382780 | Mitochondria as a target in treatment |
Q26741708 | Mitochondria, cholesterol and cancer cell metabolism |
Q28478835 | Mitochondrial electron transport is the cellular target of the oncology drug elesclomol |
Q92325768 | Mitochondrial metabolism promotes adaptation to proteotoxic stress |
Q38934404 | Mitochondrial oxidative stress as a novel therapeutic target to overcome intrinsic drug resistance in melanoma cell subpopulations |
Q35536098 | Mitochondrial peroxiredoxin III is a potential target for cancer therapy |
Q28482377 | Mitochondrial respiration--an important therapeutic target in melanoma |
Q37778064 | Molecular targeted therapy for patients with melanoma: the promise of MAPK pathway inhibition and beyond |
Q37483949 | Molecular-targeted therapy in malignant melanoma |
Q55281738 | More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of ROS and Apoptosis. |
Q40927454 | N',N'-Dimethyl-N',N'-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS). |
Q36238964 | Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration |
Q37486788 | Novel therapeutics for the treatment of metastatic melanoma |
Q94948237 | Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma |
Q36702422 | Oxidants, antioxidants and the current incurability of metastatic cancers |
Q38645501 | Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches. |
Q35587484 | Pharmacological activity of metal binding agents that alter copper bioavailability |
Q34429484 | Phenotypic screening in cancer drug discovery - past, present and future |
Q38560204 | Phytoconstituents as apoptosis inducing agents: strategy to combat cancer |
Q33853594 | Preclinical evaluation of an 131I-labeled benzamide for targeted radiotherapy of metastatic melanoma |
Q39396774 | ROS-modulated therapeutic approaches in cancer treatment. |
Q38874339 | Reactive Oxygen Species Synergize To Potently and Selectively Induce Cancer Cell Death |
Q24645584 | Redox-directed cancer therapeutics: molecular mechanisms and opportunities |
Q55560161 | Repurposing drugs to target the malaria parasite unfolding protein response. |
Q99566252 | SOX6: a double-edged sword for Ewing sarcoma |
Q39117495 | Small molecule-induced mitochondrial disruption directs prostate cancer inhibition via UPR signaling |
Q91705472 | Synthesis of an ultrasensitive BODIPY-derived fluorescent probe for detecting HOCl in live cells |
Q91600271 | Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation |
Q29616804 | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? |
Q34115304 | Targeting mitochondria for cancer therapy |
Q91137768 | Targeting mitochondria in cancer: current concepts and immunotherapy approaches |
Q92178514 | The Anticancer Agent Elesclomol Has Direct Effects on Mitochondrial Bioenergetic Function in Isolated Mammalian Mitochondria |
Q46247176 | The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression. |
Q57569574 | The role of chemotherapy in the modern management of melanoma |
Q34300200 | The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity |
Q34428947 | Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling |
Q24597964 | Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy |
Search more.