| P50 | author | Rahul Palchaudhuri | Q89607366 |
| P2093 | author name string | Paul J Hergenrother | |
| | Mirth T Hoyt | |
| P2860 | cites work | Synthesis of cribrostatin 6 | Q81899865 |
| | Isolation and structure of cribrostatins 1 and 2 from the blue marine sponge Cribrochalinasp | Q104395224 |
| | Targeting DNA topoisomerase II in cancer chemotherapy | Q24649711 |
| | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions | Q28293535 |
| | The Connectivity Map: a new tool for biomedical research | Q28530408 |
| | The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease | Q29547614 |
| | Topoisomerase I inhibitors: camptothecins and beyond | Q29614976 |
| | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Q29616804 |
| | Tumour stem cells and drug resistance | Q29617742 |
| | Genotoxicity of streptonigrin: a review | Q32062949 |
| | Mechanism of cell death induced by cis-3, 4', 5-trimethoxy-3'-aminostilbene in ovarian cancer | Q33330550 |
| | Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue | Q33398170 |
| | Paclitaxel-induced cell death: where the cell cycle and apoptosis come together | Q33947088 |
| | Molecular mechanisms involved in cisplatin cytotoxicity. | Q34058522 |
| | Elesclomol induces cancer cell apoptosis through oxidative stress | Q34812609 |
| | Molecular mechanisms of N-acetylcysteine actions | Q35076338 |
| | The Heme Oxygenase Dilemma in Cellular Homeostasis: New Insights for the Feedback Regulation of Heme Catabolism | Q35568692 |
| | Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA | Q35623960 |
| | ROS stress in cancer cells and therapeutic implications | Q35781703 |
| | SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours | Q35976983 |
| | Detection of Adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations | Q36868478 |
| | DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action | Q36995698 |
| | Tirapazamine: from bench to clinical trials. | Q37230218 |
| | Total synthesis of cribrostatin 6. | Q37467102 |
| | Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress | Q39766147 |
| | Antitumor agents 6. Synthesis, structure-activity relationships, and biological evaluation of spiro[imidazolidine-4,3'-thieno[2,3-g]quinoline]-tetraones and spiro[thieno[2,3-g]quinoline-3,5'-[1,2,4]triazinane]-tetraones with potent antiproliferative | Q39909237 |
| | An attempt to evaluate the effect of vitamin K3 using as an enhancer of anticancer agents | Q39976091 |
| | Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf2. | Q40028653 |
| | Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity. | Q40184984 |
| | Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators | Q40225712 |
| | Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase | Q40396704 |
| | Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. | Q40479948 |
| | A new screening system for proliferation-independent anti-cancer agents | Q40550341 |
| | The interaction of ethidium with synthetic double-stranded polynucleotides at low ionic strength | Q40572553 |
| | Cytotoxic isoquinoline quinones from sponges of the genus Petrosia | Q40587868 |
| | Cytotoxicity and DNA Topoisomerase Inhibitory Activity of Benz[f]indole-4,9-dione Analogs | Q40629892 |
| | Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones | Q40689586 |
| | Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathways | Q40766109 |
| | Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species | Q40871481 |
| | Haem oxygenase-1 prevents cell death by regulating cellular iron. | Q40918541 |
| | G1 versus G2 cell cycle arrest after adriamycin-induced damage in mouse Swiss3T3 cells | Q42808556 |
| | Differential responses of proliferating versus quiescent cells to adriamycin | Q42813861 |
| | The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo. | Q43541920 |
| | Effect of change in cellular GSH levels on mitochondrial damage and cell viability loss due to mitomycin c in small cell lung cancer cells | Q45080246 |
| | The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells | Q45218026 |
| | Reactive oxygen species may have antitumor activity in metastatic melanoma | Q46833370 |
| | Antineoplastic Agents. 485. Isolation and Structure of Cribrostatin 6, a Dark Blue Cancer Cell Growth Inhibitor from the Marine Sponge Cribrochalina sp.,1a | Q50494760 |
| | Sulforhodamine B colorimetric assay for cytotoxicity screening. | Q51032435 |
| | Antibacterial activity of the marine sponge constituent cribrostatin 6. | Q51787852 |
| | Cell cycle-dependent cytotoxicity, G2/M phase arrest, and disruption of p34cdc2/cyclin B1 activity induced by doxorubicin in synchronized P388 cells. | Q52519405 |
| | Cell cycle-independent regulation of p21Waf1/Cip1 and retinoblastoma protein during okadaic acid-induced apoptosis is coupled with induction of Bax protein in human breast carcinoma cells. | Q52522979 |
| | Activation of the S phase DNA damage checkpoint by mitomycin C. | Q53582963 |
| | Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells. | Q53589597 |
| | Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. | Q53624957 |
| | The problem of the quiescent cancer cell. | Q54365388 |
| | Mechanisms of multidrug resistance in HL60 cells: evidence that a surface membrane protein distinct from P-glycoprotein contributes to reduced cellular accumulation of drug. | Q54380012 |
| | The Highly Reducing Sugar 2-Deoxy-d-Ribose Induces Apoptosis in Human Fibroblasts by Reduced Glutathione Depletion and Cytoskeletal Disruption | Q60687760 |
| | Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes | Q64388057 |
| | Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II | Q64390546 |
| | Stimulation of cell growth in vitro by serum with and without growth factor. Relation to contact inhibition and viral transformation | Q67232046 |
| | The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B | Q67842878 |
| | Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I | Q70106083 |
| | Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay | Q71161492 |
| | Cytocidal action of the quinone group and its relationship to antitumor activity | Q71727111 |
| | Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110 | Q72946011 |
| | Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis | Q73755290 |
| | Clinical applications of anticancer drugs targeted to topoisomerase II | Q77333693 |
| | Topostatin, a novel inhibitor of Topoisomerases I and II produced by Thermomonospora alba strain No. 1520. II. Physico-chemical properties and structure elucidation | Q77904650 |
| | Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors | Q79666280 |
| | Cancer stem cells | Q80312237 |
| P433 | issue | 4 | |
| P921 | main subject | reactive oxygen species | Q424361 |
| P304 | page(s) | 562-573 | |
| P577 | publication date | 2010-02-20 | |
| P1433 | published in | Investigational New Drugs | Q2312231 |
| P1476 | title | Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism | |
| P478 | volume | 29 | |