| P2093 | author name string | Paul R Ortiz de Montellano | |
| | Giselle Knudsen | |
| | Clinton R Nishida | |
| | Wesley Straub | |
| P2860 | cites work | Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution | Q22008812 |
| | Regulation of endothelium-derived nitric oxide production by the protein kinase Akt | Q22010149 |
| | Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation | Q22010150 |
| | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme | Q24299059 |
| | Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes | Q24654975 |
| | Structure of a cytochrome P450-redox partner electron-transfer complex | Q27617426 |
| | Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation | Q27617498 |
| | The catalytic pathway of cytochrome p450cam at atomic resolution | Q27621595 |
| | Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module | Q27624980 |
| | Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase | Q27633641 |
| | Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures | Q27658693 |
| | Structure of nitric oxide synthase oxygenase dimer with pterin and substrate | Q27748968 |
| | Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center | Q27766420 |
| | Regulation of neuronal nitric-oxide synthase by calmodulin kinases | Q28139282 |
| | The Akt kinase signals directly to endothelial nitric oxide synthase | Q28609847 |
| | Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family | Q30195728 |
| | Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase. | Q31446994 |
| | Transport and metabolism of agmatine in rat hepatocyte cultures | Q31944462 |
| | The mechanism of heme oxygenase | Q33878368 |
| | Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant | Q34461803 |
| | Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase | Q34583665 |
| | Calmodulin is a subunit of nitric oxide synthase from macrophages | Q36231600 |
| | Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer | Q36672374 |
| | Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide | Q37310818 |
| | Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase | Q37368113 |
| | Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: deformylation with olefin formation | Q37604062 |
| | Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains | Q37677604 |
| | Removal of a putative inhibitory element reduces the calcium-dependent calmodulin activation of neuronal nitric-oxide synthase | Q38315488 |
| | Characterization of the reductase domain of rat neuronal nitric oxide synthase generated in the methylotrophic yeast Pichia pastoris. Calmodulin response is complete within the reductase domain itself | Q38353903 |
| | High reductase activity of recombinant NOS2 flavoprotein domain lacking the calmodulin binding regulatory sequence. | Q38360129 |
| | Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer | Q40884539 |
| | Mechanistic studies on aromatase and related C-C bond cleaving P-450 enzymes | Q40898439 |
| | Structural domains of P450-containing monooxygenase systems | Q40990985 |
| | Reaction of neuronal nitric-oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin. | Q41037639 |
| | Formation of N delta-cyanoornithine from NG-hydroxy-L-arginine and hydrogen peroxide by neuronal nitric oxide synthase: implications for mechanism | Q41077009 |
| | Some aspects of the role of cytochrome P-450 isozymes in the N-oxidative transformation of secondary and tertiary amine compounds | Q41144879 |
| | Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases | Q41215964 |
| | Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase | Q41369987 |
| | Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element | Q41665327 |
| | An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase | Q42667464 |
| | Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin | Q42988594 |
| | Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity | Q43547759 |
| | Control of electron transfer in nitric-oxide synthases. Swapping of autoinhibitory elements among nitric-oxide synthase isoforms | Q43551085 |
| | Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis. | Q43717031 |
| | Oxidation of N(omega)-hydroxyarginine analogues by NO-synthase: the simple, non amino acid N-butyl N'-hydroxyguanidine is almost as efficient an NO precursor as N(omega)-hydroxyarginine | Q43742621 |
| | Human endothelial nitric oxide synthase: expression in Escherichia coli, coexpression with calmodulin, and characterization | Q43812755 |
| | Oxidation of the meso-methylmesoheme regioisomers by heme oxygenase. Electronic control of the reaction regiospecificity | Q46487701 |
| | Active site topologies and cofactor-mediated conformational changes of nitric-oxide synthases | Q46505648 |
| | Oxidation of alpha-meso-formylmesoheme by heme oxygenase. Electronic control of the reaction regiospecificity | Q46881853 |
| | Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine | Q47813228 |
| | Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer. | Q47828364 |
| | Nitric oxide synthase is a cytochrome P-450 type hemoprotein | Q48453994 |
| | Calcium binding sites of calmodulin and electron transfer by neuronal nitric oxide synthase. | Q52559011 |
| | Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin. | Q54562262 |
| | The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin | Q57219640 |
| | The C terminus of mouse macrophage inducible nitric-oxide synthase attenuates electron flow through the flavin domain | Q57219760 |
| | Formation of a Pterin Radical in the Reaction of the Heme Domain of Inducible Nitric Oxide Synthase with Oxygen† | Q57837809 |
| | Stoichiometric Arginine Binding in the Oxygenase Domain of Inducible Nitric Oxide Synthase Requires a Single Molecule of Tetrahydrobiopterin per Dimer | Q57908357 |
| | Low-Temperature Optical Absorption Spectra Suggest a Redox Role for Tetrahydrobiopterin in Both Steps of Nitric Oxide Synthase Catalysis† | Q61906284 |
| | Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes | Q70051942 |
| | NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins | Q70288047 |
| | Metabolic N-oxide formation by rabbit-liver microsomal cytochrome P-4502B4: involvement of superoxide in the NADPH-dependent N-oxygenation of N,N-dimethylaniline | Q70470329 |
| | Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2+ | Q71514652 |
| | Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s | Q72077563 |
| | Mechanism of the acyl-carbon cleavage and related reactions catalyzed by multifunctional P-450s: studies on cytochrome P-450(17)alpha | Q72357803 |
| | The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer | Q73083205 |
| | Calmodulin promotes dimerization of the oxygenase domain of human endothelial nitric-oxide synthase | Q73257875 |
| | Calmodulin activates intramolecular electron transfer between the two flavins of neuronal nitric oxide synthase flavin domain | Q73264356 |
| | Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases | Q73441813 |
| | Intra-subunit and inter-subunit electron transfer in neuronal nitric-oxide synthase: effect of calmodulin on heterodimer catalysis | Q73981397 |
| | Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase | Q74023902 |
| | Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism | Q74182276 |
| | Electron transfer and catalytic activity of nitric oxide synthases. Chimeric constructs of the neuronal, inducible, and endothelial isoforms | Q74263656 |
| | Efficient formation of nitric oxide from selective oxidation of N-aryl N'-hydroxyguanidines by inducible nitric oxide synthase | Q77314145 |
| | Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase | Q77501939 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 479-501 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | Drug Metabolism Reviews | Q5308857 |
| P1476 | title | Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase | |
| P478 | volume | 34 | |