Histone Demethylases in Colon Cancer

scientific article

Histone Demethylases in Colon Cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11888-014-0253-2
P932PMC publication ID4283932
P698PubMed publication ID25574158
P5875ResearchGate publication ID267628112

P2093author name stringDharmalingam Subramaniam
Satish Ramalingam
Shrikant Anant
Santanu Paul
Animesh Dhar
Joaquina Baranda
P2860cites workTranslating the Histone CodeQ22065840
p53 is regulated by the lysine demethylase LSD1Q24292925
The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1Q24306590
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancerQ24308737
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcriptionQ24312958
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylasesQ24315937
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1Q24336747
Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic ApproachesQ27659044
Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST ComplexQ27666875
Wnt/beta-catenin signaling in development and diseaseQ27860784
Cancer statistics, 2014Q27861018
Histone demethylation by a family of JmjC domain-containing proteinsQ27939224
Corepressor-dependent silencing of chromosomal regions encoding neuronal genesQ28210691
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapyQ28235397
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylationQ28265681
Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biologyQ28269080
Regulation of LSD1 histone demethylase activity by its associated factorsQ28270391
Human PAD4 regulates histone arginine methylation levels via demethyliminationQ28280359
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogrammingQ28284694
Histone demethylases in development and diseaseQ28293982
Wnt signalling and the mechanistic basis of tumour developmentQ28301804
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylationQ28304726
Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancerQ28482156
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomasQ28592004
Histone methyltransferases in cancerQ29042217
The diverse functions of histone lysine methylationQ29614523
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coliQ29618092
Wnt signalling and its impact on development and cancerQ29619273
Molecular identification of a danger signal that alerts the immune system to dying cellsQ29619497
Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules.Q30496670
Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasionQ42534955
A histone H3 methyltransferase controls DNA methylation in Neurospora crassaQ42664087
Epigenetic control and cancer: the potential of histone demethylases as therapeutic targetsQ42922825
LSD1 is required for chromosome segregation during mitosisQ43147492
X-linked genes in female embryonic stem cells carry an epigenetic mark prior to the onset of X inactivationQ44521166
Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.Q53286652
Dynamic regulation of histone H3 methylation at lysine 4 in mammalian spermatogenesis.Q53540526
Histone lysine demethylases and their impact on epigenetics.Q53626346
Demethylation of the zygotic paternal genomeQ59066150
Mitochondria and the death of oocytesQ59075483
Positive expression of LSD1 and negative expression of E-cadherin correlate with metastasis and poor prognosis of colon cancerQ85893330
Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: in vivo identification from hypoxic tumor cellsQ33686615
Induction and regulation of epithelial-mesenchymal transitionsQ34047215
Epigenetic consequences of nucleosome dynamicsQ34157982
Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stabilityQ34178072
Role of lysine methylation of NF-κB in differential gene regulationQ34361051
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.Q34391011
Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 DemethylasesQ34458438
Wnt signaling: is the party in the nucleus?Q34534188
Histone methylation: dynamic or static?Q34731355
Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].Q34905762
Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherinQ35384921
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genesQ35762084
Epithelial-mesenchymal transitions: twist in development and metastasisQ35856121
Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.Q35860815
A crack in histone lysine methylation.Q35994114
Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesisQ36434436
Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.Q36474544
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemiaQ36515569
Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners.Q36639638
Wnt signaling pathway in mammary gland development and carcinogenesisQ36741848
A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.Q36805141
Expression of the zinc-finger transcription factor Snail in adrenocortical carcinoma is associated with decreased survivalQ37010522
Histone lysine demethylases as targets for anticancer therapyQ38162717
The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent mannersQ38303012
LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancerQ39117867
A high level of integrin α6 expression in human intrahepatic cholangiocarcinoma cells is associated with a migratory and invasive phenotypeQ39212755
Cryptotanshinone down-regulates androgen receptor signaling by modulating lysine-specific demethylase 1 function.Q39448281
KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cellsQ39479710
RCOR2 is a subunit of the LSD1 complex that regulates ESC property and substitutes for SOX2 in reprogramming somatic cells to pluripotencyQ39571419
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.Q39671569
Lysine methylation regulates E2F1-induced cell deathQ39684254
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancersQ39723644
Methylation: lost in hydroxylation?Q40110203
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferationQ40158574
Histone demethylase LSD1 regulates adipogenesisQ41852966
P433issue4
P304page(s)417-424
P577publication date2014-12-01
P1433published inCurrent colorectal cancer reportsQ26842259
P1476titleHistone Demethylases in Colon Cancer
P478volume10

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cites work (P2860)
Q36907727Epigenetics and Colorectal Neoplasia: the Evidence for Physical Activity and Sedentary Behavior
Q37295663IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer