The conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors

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The conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1529/BIOPHYSJ.106.082610
P932PMC publication ID1518631
P698PubMed publication ID16698782
P5875ResearchGate publication ID7082260

P50authorAngela F DulhuntyQ62035694
P2093author name stringLan Wei
Nicole A Beard
Magdolna Varsányi
P2860cites workThe role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calciumQ24319842
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Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membraneQ28248323
Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes.Q28344499
Different Ca2+ releasing action of caffeine and depolarisation in skeletal muscle fibres of the ratQ28360326
Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channelsQ28366867
Polymerization of calsequestrin. Implications for Ca2+ regulationQ31132192
Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulumQ33257655
Excitation-contraction coupling in skeletal muscle: comparisons with cardiac muscleQ33879461
The asp-rich region at the carboxyl-terminus of calsequestrin binds to Ca(2+) and interacts with triadinQ33927847
Calsequestrin and the calcium release channel of skeletal and cardiac muscleQ33976992
Sarcoplasmic reticulum lumenal Ca2+ has access to cytosolic activation and inactivation sites of skeletal muscle Ca2+ release channelQ34017877
Abnormal ryanodine receptor channels in malignant hyperthermiaQ34125636
Regulation of cardiac muscle Ca2+ release channel by sarcoplasmic reticulum lumenal Ca2+Q34169317
Regulation of the cardiac ryanodine receptor channel by luminal Ca2+ involves luminal Ca2+ sensing sitesQ34169533
Activation and inhibition of skeletal RyR channels by a part of the skeletal DHPR II-III loop: effects of DHPR Ser687 and FKBP12.Q34170813
Effects of cytoplasmic and luminal pH on Ca(2+) release channels from rabbit skeletal muscleQ34172783
Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation.Q34190203
Association of triadin with the ryanodine receptor and calsequestrin in the lumen of the sarcoplasmic reticulumQ34308863
Depletion "skraps" and dynamic buffering inside the cellular calcium store.Q34479895
Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscleQ36211309
Characterization of the junctional face membrane from terminal cisternae of sarcoplasmic reticulumQ36215288
The structure of calsequestrin in triads of vertebrate skeletal muscle: a deep-etch studyQ36218009
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ storesQ36405355
Luminal Ca2+-regulated Mg2+ inhibition of skeletal RyRs reconstituted as isolated channels or coupled clustersQ36445732
Luminal calcium regulates calcium release in triads isolated from frog and rabbit skeletal muscleQ39651113
Sulfhydryl oxidation modifies the calcium dependence of ryanodine-sensitive calcium channels of excitable cellsQ40116702
Receptor-activated Ca2+ influx: how many mechanisms for how many channels?Q40752868
Complete amino acid sequence of canine cardiac calsequestrin deduced by cDNA cloningQ42658152
Calsequestrin: more than 'only' a luminal Ca2+ buffer inside the sarcoplasmic reticulumQ42992388
Redox sensing properties of the ryanodine receptor complexQ43980937
Interaction of divalent cations with the 55,000-dalton protein component of the sarcoplasmic reticulum. Studies of fluorescence and circular dichroismQ44556259
Depletion of intracellular calcium stores activates a calcium current in mast cellsQ45345621
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979.Q49012176
Regulation of the purified Ca2+ release channel/ryanodine receptor complex of skeletal muscle sarcoplasmic reticulum by luminal calcium.Q53988314
The gating of the sheep skeletal sarcoplasmic reticulum Ca(2+)-release channel is regulated by luminal Ca2+.Q54007962
Single channel activity of the ryanodine receptor calcium release channel is modulated by FK-506.Q54022385
Ryanodine receptor of skeletal muscle is a gap junction-type channel.Q54120666
Effects of Cation Binding on the Conformation of Calsequestrin and the High Affinity Calcium-binding Protein of Sarcoplasmic ReticulumQ68924946
Regulation of calcium release by calcium inside the sarcoplasmic reticulum in ventricular myocytesQ71468223
Ruthenium red modifies the cardiac and skeletal muscle Ca(2+) release channels (ryanodine receptors) by multiple mechanismsQ73157291
Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanismsQ73207956
Evidence for Ca(2+) activation and inactivation sites on the luminal side of the cardiac ryanodine receptor complexQ74113980
Dual regulation of the skeletal muscle ryanodine receptor by triadin and calsequestrinQ77299816
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1288-1301
P577publication date2006-05-12
P1433published inBiophysical JournalQ2032955
P1476titleThe conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors
P478volume91

Reverse relations

cites work (P2860)
Q35126961A new cytoplasmic interaction between junctin and ryanodine receptor Ca2+ release channels
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Q28578879Altered expression of triadin 95 causes parallel changes in localized Ca2+ release events and global Ca2+ signals in skeletal muscle cells in culture
Q28511309Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice
Q47709918Association of FK506 binding proteins with RyR channels - effect of CLIC2 binding on sub-conductance opening and FKBP binding.
Q35312872C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition
Q37478186Ca(2+) signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin
Q36517766Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians.
Q104111317Calsequestrin: a well-known but curious protein in skeletal muscle
Q34339135Cardiac ryanodine receptor activation by a high Ca²⁺ store load is reversed in a reducing cytoplasmic redox environment.
Q35063164Cyclization of the intrinsically disordered α1S dihydropyridine receptor II-III loop enhances secondary structure and in vitro function.
Q34505928Functional and structural characterization of a eurytolerant calsequestrin from the intertidal teleost Fundulus heteroclitus
Q38056435Functional interaction between calsequestrin and ryanodine receptor in the heart
Q37422708Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin
Q82749646Lessons from calsequestrin-1 ablation in vivo: much more than a Ca(2+) buffer after all
Q36565789Novel regulators of RyR Ca2+ release channels: insight into molecular changes in genetically-linked myopathies.
Q38587629Organization of junctional sarcoplasmic reticulum proteins in skeletal muscle fibers.
Q38004648Proteins within the intracellular calcium store determine cardiac RyR channel activity and cardiac output
Q38325324Regulation of RYR2 by sarcoplasmic reticulum Ca(2+).
Q28078420Review of RyR1 pathway and associated pathomechanisms
Q24298576Role of Junctin protein interactions in cellular dynamics of calsequestrin polymer upon calcium perturbation
Q37799093Ryanodine receptor assembly: A novel systems biology approach to 3D mapping
Q37373399Ryanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms
Q28576166The catecholaminergic polymorphic ventricular tachycardia mutation R33Q disrupts the N-terminal structural motif that regulates reversible calsequestrin polymerization
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Q36296083Triadin binding to the C-terminal luminal loop of the ryanodine receptor is important for skeletal muscle excitation contraction coupling

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