| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1034/J.1600-065X.2002.18609.X |
| P698 | PubMed publication ID | 12234365 |
| P2093 | author name string | Janis K Burkhardt | |
| Judy L Cannon | |||
| P2860 | cites work | Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein | Q22009957 |
| Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein | Q22253357 | ||
| Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton | Q22253423 | ||
| WIP regulates N-WASP-mediated actin polymerization and filopodium formation | Q24291191 | ||
| Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization | Q24309118 | ||
| WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells | Q24315106 | ||
| Isolation of a novel gene mutated in Wiskott-Aldrich syndrome | Q24317943 | ||
| Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains | Q24651136 | ||
| The immunological synapse: a molecular machine controlling T cell activation | Q28139151 | ||
| A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization | Q28139787 | ||
| Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex | Q28142313 | ||
| T cell receptor signaling precedes immunological synapse formation | Q28203073 | ||
| WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation | Q28204198 | ||
| Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin | Q28205072 | ||
| Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin | Q28208110 | ||
| Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex | Q36450248 | ||
| T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help | Q37132260 | ||
| Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells | Q37384846 | ||
| CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1. | Q39540043 | ||
| Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential | Q39549098 | ||
| Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1. | Q40243330 | ||
| Rho-related proteins: actin cytoskeleton and cell cycle | Q40525077 | ||
| Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70. | Q40769856 | ||
| N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility | Q40777112 | ||
| Polarity of T cell shape, motility, and sensitivity to antigen | Q41202887 | ||
| Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts | Q41649492 | ||
| A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation. | Q41724589 | ||
| Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins. | Q41734676 | ||
| LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain | Q42837762 | ||
| Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis | Q42951587 | ||
| F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts. | Q43867810 | ||
| Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells | Q43930610 | ||
| Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction | Q46517603 | ||
| Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation | Q47713209 | ||
| Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome | Q47801687 | ||
| Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. | Q52124332 | ||
| Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap | Q57185247 | ||
| Plagiarism and Pathogenesis | Q58163276 | ||
| PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes | Q58617364 | ||
| Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome | Q77530724 | ||
| Separation of integrin-dependent adhesion from morphological changes based on differential PLC specificities | Q77787140 | ||
| Three-dimensional segregation of supramolecular activation clusters in T cells | Q28282528 | ||
| Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome | Q28289697 | ||
| Identification of Itk/Tsk Src homology 3 domain ligands | Q28290110 | ||
| Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells | Q28585061 | ||
| The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly | Q28609843 | ||
| Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex | Q28609852 | ||
| Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76 | Q28647329 | ||
| Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate | Q28647599 | ||
| Rho GTPases control polarity, protrusion, and adhesion during cell movement | Q29614244 | ||
| Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation | Q30167979 | ||
| A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events | Q30168538 | ||
| The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling | Q30175876 | ||
| Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling | Q30633083 | ||
| Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus | Q33495013 | ||
| Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome | Q33503405 | ||
| Cytoskeletal rearrangement during migration and activation of T lymphocytes | Q33650492 | ||
| Small GTPases in lymphocyte biology: Rho proteins take center stage | Q33723093 | ||
| Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase | Q33786920 | ||
| A homochiral metal-organic porous material for enantioselective separation and catalysis | Q33901022 | ||
| T cell activation and the cytoskeleton | Q33932683 | ||
| The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. | Q33958592 | ||
| WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development | Q34012902 | ||
| Avidity regulation of integrins: the driving force in leukocyte adhesion | Q34026256 | ||
| Surfing pathogens and the lessons learned for actin polymerization. | Q34123309 | ||
| The immunological synapse. | Q34178149 | ||
| Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42 | Q34284892 | ||
| Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. | Q36107275 | ||
| T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome | Q36231740 | ||
| A role for Cdc42 in macrophage chemotaxis | Q36264673 | ||
| Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism | Q36276679 | ||
| Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells | Q36294111 | ||
| Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions | Q36363083 | ||
| Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes | Q36375520 | ||
| Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast | Q36382423 | ||
| P304 | page(s) | 90-99 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | The regulation of actin remodeling during T-cell-APC conjugate formation | |
| P478 | volume | 186 |
| Q92556942 | A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation |
| Q34383550 | A signaling network stimulated by β2 integrin promotes the polarization of lytic granules in cytotoxic cells |
| Q28771478 | ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation |
| Q37639578 | Age-related defects in the cytoskeleton signaling pathways of CD4 T cells |
| Q24338747 | CD4 raft association and signaling regulate molecular clustering at the immunological synapse site |
| Q37438194 | Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells |
| Q34030907 | Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue |
| Q53587934 | Centrosome polarization delivers secretory granules to the immunological synapse. |
| Q45215158 | Chemical inhibitors when timing is critical: a pharmacological concept for the maturation of T cell contacts |
| Q40585986 | Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. |
| Q36617066 | Crystal structures and inhibitors of proteins involved in IL-2 release and T cell signaling |
| Q41074693 | Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation |
| Q37344247 | Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity |
| Q33859452 | Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation |
| Q28511680 | Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells |
| Q45159091 | Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. |
| Q81370939 | Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse |
| Q34718881 | Effects of low-shear modeled microgravity on cell function, gene expression, and phenotype in Saccharomyces cerevisiae |
| Q35564874 | Emerging and diverse roles of protein kinase C in immune cell signalling |
| Q35096692 | GTPases and T cell activation |
| Q36786805 | Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells |
| Q37497535 | Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity |
| Q39522922 | IQGAP1 involvement in MTOC and granule polarization in NK-cell cytotoxicity |
| Q35091278 | Impairment of immunological synapse formation in adaptively tolerant T cells |
| Q40327708 | Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8+ CTLs |
| Q36158629 | Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP. |
| Q24336759 | Kv7.1 surface expression is regulated by epithelial cell polarization |
| Q36343541 | Lymphocyte calcium signaling from membrane to nucleus |
| Q41865904 | Modeling of B cell Synapse Formation by Monte Carlo Simulation Shows That Directed Transport of Receptor Molecules Is a Potential Formation Mechanism |
| Q26744638 | Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation |
| Q35606218 | Regulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupe |
| Q37235232 | Retractile processes in T lymphocyte orientation on a stimulatory substrate: morphology and dynamics. |
| Q33754402 | RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling |
| Q33571098 | SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cells |
| Q36325591 | Semaphorins command cells to move |
| Q39671656 | Sustained LFA‐1 cluster formation in the immune synapse requires the combined activities of L‐plastin and calmodulin |
| Q35576652 | T-cell integrins: more than just sticking points |
| Q36085610 | TEC-family kinases: regulators of T-helper-cell differentiation |
| Q36877295 | Tec kinases, actin, and cell adhesion |
| Q30483756 | The Ca(2+)-activated K(+) channel KCa3.1 compartmentalizes in the immunological synapse of human T lymphocytes. |
| Q30478842 | The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation |
| Q36229690 | The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells |
| Q33936852 | The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein |
| Q33671893 | Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation |
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