Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

scientific article (publication date: November 2001)

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1074-7613(01)00231-X
P3181OpenCitations bibliographic resource ID957734
P698PubMed publication ID11728332
P5875ResearchGate publication ID11628220

P2093author name stringK Kaibuchi
R N Germain
J Delon
P2860cites workRho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytesQ40918897
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Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complexQ42946982
Receptor-directed focusing of lymphokine release by helper T cellsQ44044768
The duration of antigenic stimulation determines the fate of naive and effector T cells.Q51099389
Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.Q54106494
The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytesQ73228101
Absence of CD43 fails to alter T cell development and responsivenessQ73311837
Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytesQ73538023
Protein kinase C-theta phosphorylation of moesin in the actin-binding sequenceQ74358920
Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium responseQ74375728
A receptor/cytoskeletal movement triggered by costimulation during T cell activationQ77696385
Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structuresQ77696515
C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeletonQ77905807
Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndromeQ24303591
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathwayQ24598098
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2Q24676628
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail associationQ24678197
Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarizationQ24683747
The immunological synapse: a molecular machine controlling T cell activationQ28139151
Protein phosphatase 2C inactivates F-actin binding of human platelet moesinQ28144127
Three-dimensional segregation of supramolecular activation clusters in T cellsQ28282528
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contactsQ28282813
Selective modulation of protein kinase C-theta during T-cell activationQ28300613
Negative regulation of T-cell adhesion and activation by CD43Q28508953
CD43 is a murine T cell costimulatory receptor that functions independently of CD28Q28586182
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activationQ30491549
ERM proteins in cell adhesion and membrane dynamicsQ33632981
Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteinsQ33780874
From synapses to immunological memory: the role of sustained T cell stimulationQ33840553
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognitionQ33867251
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell deathQ33876302
T cell activation and the cytoskeletonQ33932683
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.Q33958592
ERM-Merlin and EBP50 protein families in plasma membrane organization and functionQ34059680
Information transfer at the immunological synapse.Q34117443
The immunological synapse.Q34178149
Synaptic pattern formation during cellular recognitionQ36225863
Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteinsQ36256564
Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphataseQ36289185
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletonsQ36382880
Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cellsQ36404256
The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cellsQ36420019
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family membersQ36534860
Replacement of threonine 558, a critical site of phosphorylation of moesin in vivo, with aspartate activates F-actin binding of moesin. Regulation by conformational changeQ38325656
Differential clustering of CD4 and CD3zeta during T cell recognitionQ40859028
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
phosphorylationQ242736
P304page(s)691-701
P577publication date2001-11-01
P1433published inImmunityQ6005457
P1476titleExclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
P478volume15

Reverse relations

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