Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin

scientific article

Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200707199
P932PMC publication ID2080902
P698PubMed publication ID18025306
P5875ResearchGate publication ID5822529

P2093author name stringMing Zhou
Anthony Bretscher
Tal Ilani
Timothy D Veenstra
Chand Khanna
P2860cites workZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chainQ24294340
Moesin: a member of the protein 4.1-talin-ezrin family of proteinsQ24314954
Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding siteQ24617964
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathwayQ24671083
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2Q24676628
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrinQ24676944
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail associationQ24678197
Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin familyQ24678695
A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterizationQ24679495
Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cellsQ24681337
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signalingQ25257443
Defective recruitment and activation of ZAP-70 in common variable immunodeficiency patients with T cell defectsQ61522596
Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cellsQ72572435
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domainQ27622801
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligationQ28198175
A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sitesQ28202167
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranesQ28204937
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesinQ28208110
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiencyQ28254730
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contactsQ28272939
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapseQ28507578
Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockoutQ28508442
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestineQ28510081
The importance of cross-linking in the homotypic aggregation of lymphocytes induced by anti-leukosialin (CD43) antibodiesQ28564332
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cellsQ28585061
ERM proteins and merlin: integrators at the cell cortexQ29619893
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereociliaQ30496716
Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activationQ33890664
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.Q33958592
FERMing up the synapse.Q34453049
Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activationQ35005880
Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domainQ35633077
Role of the cytoskeleton during leukocyte responsesQ35709644
Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factorQ36219929
Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4Q36228702
ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domainsQ36266883
T cell receptor ligation induces the formation of dynamically regulated signaling assembliesQ36324026
Radixin is a novel member of the band 4.1 familyQ36532958
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family membersQ36534860
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrityQ40679590
Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptorsQ41094201
Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cellsQ41554017
Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localizationQ42606501
Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein familyQ42720142
Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarizationQ43442700
ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1.Q44184963
Radixin is a component of hepatocyte microvilli in situQ46381117
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.Q46793124
Lumen morphogenesis in C. elegans requires the membrane-cytoskeleton linker erm-1.Q47068922
Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype.Q53379260
Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.Q54106494
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarizationQ58022542
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)733-746
P577publication date2007-11-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleImmune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin
P478volume179

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cites work (P2860)
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