Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice

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Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...512404S
P356DOI10.1371/JOURNAL.PONE.0012404
P932PMC publication ID2929185
P698PubMed publication ID20806059
P5875ResearchGate publication ID46096011

P50authorAnne I SperlingQ57334498
Judy L CannonQ57552170
Janis K BurkhardtQ57586209
P2093author name stringAvinash Bhandoola
John K Choi
Ichiko Saotome
Andrea I McClatchey
Terri M Laufer
Evann Corbo
Gregory F Wu
Jonathan S Maltzman
Yanping Huang
Paula M Oliver
Meredith H Shaffer
Marielena Velez
P2860cites workCD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathwayQ24598098
A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sitesQ28202167
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranesQ28204937
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesinQ28208110
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapseQ28507578
Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockoutQ28508442
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestineQ28510081
Efficient in vivo manipulation of mouse genomic sequences at the zygote stageQ29547306
ERM proteins and merlin: integrators at the cell cortexQ29619893
The cytoplasmic tail of L-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not EzrinQ31029868
Tight junction-related structures in the absence of a lumen: occludin, claudins and tight junction plaque proteins in densely packed cell formations of stratified epithelia and squamous cell carcinomasQ34268423
The distal pole complex: a novel membrane domain distal to the immunological synapseQ35005877
Enhanced histopathology of the thymus.Q35641398
Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesinQ36149269
Calpain regulates actin remodeling during cell spreadingQ36255313
Ezrin and moesin function together to promote T cell activation.Q36379032
Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cellsQ36740558
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrityQ40679590
The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3.Q40999069
Microvilli defects in retinas of ezrin knockout miceQ42486471
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchangerQ47852356
Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.Q54106494
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarizationQ58022542
Fate of Subcutaneous Thymus Grafts in Thymectomized Mice inoculated with Leukæmic FiltrateQ58939218
Identification and Relevance of the CD95-binding Domain in the N-terminal Region of EzrinQ60687734
ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugationQ63408325
Dexamethasone and 2,3,7,8-tetrachlorodibenzo-p-dioxin can induce thymic atrophy by different mechanisms in miceQ70227904
The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activationQ77307336
Attenuated response to liver injury in moesin-deficient mice: impaired stellate cell migration and decreased fibrosisQ81593753
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectthymocyteQ7799635
P304page(s)e12404
P577publication date2010-08-27
P1433published inPLOS OneQ564954
P1476titleEzrin is highly expressed in early thymocytes, but dispensable for T cell development in mice
P478volume5

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cites work (P2860)
Q35681855Expression of ezrin in human embryonic, fetal, and normal adult tissues
Q37256630Ezrin tunes the magnitude of humoral immunity
Q38151846Re-defining ERM function in lymphocyte activation and migration
Q58195107Sequential binding of ezrin and moesin to L-selectin regulates monocyte protrusive behaviour during transendothelial migration

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