Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis

scientific article (publication date: 9 April 2004)

Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M312659200
P698PubMed publication ID14729663

P50authorOreste AcutoQ28946362
P2093author name stringChrystelle Brignone
Arnaud Foussat
Marcel Deckert
Isabelle Foucault
Séverine Le Bras
P2860cites workA novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1Q22010811
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonQ22253423
SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptorsQ24530648
Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signalingQ24537487
The ADF homology (ADF-H) domain: a highly exploited actin-binding moduleQ24647366
Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysisQ27635472
Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I.Q27936873
Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinaseQ28198246
T cell receptor signaling precedes immunological synapse formationQ28203073
Mammalian actin binding protein 1 is essential for endocytosis but not lamellipodia formation: functional analysis by RNA interferenceQ28207068
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesinQ28208110
Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytesQ28211046
Three-dimensional segregation of supramolecular activation clusters in T cellsQ28282528
Functional and physical interactions of Syk family kinases with the Vav proto-oncogene productQ28300755
Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activationQ28591682
Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76Q28647329
Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activationQ30167979
p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cellsQ30176832
How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structuresQ33840324
T cell activation and the cytoskeletonQ33932683
Signal transduction mediated by the T cell antigen receptor: the role of adapter proteinsQ34115639
c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulationQ34157660
The immunological synapse.Q34178149
Antigen decoding by T lymphocytes: from synapses to fate determinationQ34263452
Abp1p and cortactin, new "hand-holds" for actinQ34342054
Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strengthQ34520749
Positive and negative regulation of T-cell activation by adaptor proteinsQ34572179
Formation and function of the immunological synapseQ34612487
All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeletonQ35076710
Negative regulation of TCR signaling and T-cell activation by selective protein degradationQ35145782
Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskeleton, and protein kinasesQ36236870
On the dynamics of TCR:CD3 complex cell surface expression and downmodulationQ40837872
T regulatory cells 1 inhibit a Th2-specific response in vivoQ40846695
HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.Q41734011
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeletonQ42942785
Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulationQ42947974
The immunological synapse balances T cell receptor signaling and degradationQ44598368
The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.Q46014500
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transductionQ46517603
Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activationQ47713209
Characterization of effector-target conjugates for cloned human natural killer and human lymphokine activated killer cells by flow cytometryQ52481004
Mammalian Abp1, a Signal-Responsive F-Actin–Binding Protein, Links the Actin Cytoskeleton to Endocytosis via the Gtpase DynaminQ57373370
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectendocytosisQ189814
P304page(s)15550-60
P577publication date2004-04-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleRecruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis
P478volume279

Reverse relations

cites work (P2860)
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Q24297487Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55
Q33919559Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways
Q33794550Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation.
Q30157056Actin-binding protein-1 interacts with WASp-interacting protein to regulate growth factor-induced dorsal ruffle formation
Q37919427Actin-depolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics
Q38151851Actin-mediated feedback loops in B-cell receptor signaling
Q40451605Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.
Q40341387Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death
Q36251289Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance
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Q42111672Downregulation of RhoA and changes in T cell cytoskeleton correlate with the abrogation of allograft rejection
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Q31162565Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.
Q88227469Gene expression profiling in healthy newborns from diverse localities of the Czech Republic
Q24529866HIP-55 is important for T-cell proliferation, cytokine production, and immune responses
Q33687227HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion
Q54641391HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.
Q42947729Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response
Q79370627Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses
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Q36163456Quantitative phosphoproteomic analysis reveals a role for serine and threonine kinases in the cytoskeletal reorganization in early T cell receptor activation in human primary T cells
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