| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1034/J.1600-065X.2003.00004.X |
| P698 | PubMed publication ID | 12614363 |
| P2093 | author name string | Lawrence E Samelson | |
| Claudette L Fuller | |||
| Vivian L Braciale | |||
| P2860 | cites work | The essential role of profilin in the assembly of actin for microspike formation | Q22008023 |
| WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac | Q22008483 | ||
| Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase | Q22010473 | ||
| Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics | Q22010790 | ||
| Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton | Q22253423 | ||
| Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation | Q22254014 | ||
| IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling | Q24290667 | ||
| WIP regulates N-WASP-mediated actin polymerization and filopodium formation | Q24291191 | ||
| Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. | Q24300262 | ||
| Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation | Q24301158 | ||
| Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production | Q24314382 | ||
| A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT. | Q24536674 | ||
| Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells | Q24599228 | ||
| Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains | Q24651136 | ||
| A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42 | Q24670450 | ||
| Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice | Q24671578 | ||
| The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis | Q24675300 | ||
| On the mechanism of unidirectional killing in mixtures of two cytotoxic T lymphocytes. Unidirectional polarization of cytoplasmic organelles and the membrane-associated cytoskeleton in the effector cell | Q24682926 | ||
| An actin nucleation mechanism mediated by Bni1 and profilin | Q27938654 | ||
| Regulation and functions of Rho-associated kinase | Q28138022 | ||
| The role of membrane-associated adaptors in T cell receptor signalling | Q28139105 | ||
| The immunological synapse: a molecular machine controlling T cell activation | Q28139151 | ||
| Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3 | Q28139753 | ||
| Pak to the future | Q28142927 | ||
| Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases | Q28143793 | ||
| cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains | Q28143912 | ||
| alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase | Q28145949 | ||
| Cortactin: coupling membrane dynamics to cortical actin assembly | Q28199365 | ||
| Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton | Q28202663 | ||
| The immunological synapse | Q57962316 | ||
| The intracellular distribution of cell organelles in natural killer cells during the cytolysis of bound tumor cells, with special reference to the rod-cored vesicles | Q70167415 | ||
| Normal T cells express two T cell antigen receptor populations, one of which is linked to the cytoskeleton via zeta chain and displays a unique activation-dependent phosphorylation pattern | Q71246238 | ||
| Multiple antigens are altered on T and B lymphocytes from peripheral blood and spleen of patients with Wiskott-Aldrich syndrome | Q71778729 | ||
| The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes | Q73228101 | ||
| Cutting edge: WIP, a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation | Q73520503 | ||
| LAT is essential for Fc(epsilon)RI-mediated mast cell activation | Q73867624 | ||
| Physiological regulation of the immunological synapse by agrin | Q73873116 | ||
| Kissing cousins: immunological and neurological synapses | Q74108041 | ||
| CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis | Q74844499 | ||
| Tir - Nck's new afficionado | Q77219660 | ||
| The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation | Q77307336 | ||
| Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly | Q77452189 | ||
| Actin' up (and down) | Q77658447 | ||
| A receptor/cytoskeletal movement triggered by costimulation during T cell activation | Q77696385 | ||
| Neuropilin-1: another neuronal molecule in the "immunological synapse" | Q78010071 | ||
| WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation | Q28204198 | ||
| Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin | Q28208110 | ||
| Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck | Q28218186 | ||
| The Eph family of receptors | Q28251298 | ||
| The ephrins and Eph receptors in neural development | Q28266706 | ||
| Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells | Q28271249 | ||
| The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck | Q28278822 | ||
| Three-dimensional segregation of supramolecular activation clusters in T cells | Q28282528 | ||
| Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases | Q28289727 | ||
| Identification of Itk/Tsk Src homology 3 domain ligands | Q28290110 | ||
| Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains | Q28291074 | ||
| ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse | Q28507578 | ||
| Mena is required for neurulation and commissure formation | Q28588447 | ||
| Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics | Q28590972 | ||
| Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex | Q28609852 | ||
| Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities | Q28609857 | ||
| Lck regulates Vav activation of members of the Rho family of GTPases | Q28610619 | ||
| Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate | Q28647599 | ||
| Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility | Q29618423 | ||
| ERM proteins and merlin: integrators at the cell cortex | Q29619893 | ||
| Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation | Q30167979 | ||
| Distinct binding patterns of HS1 to the Src SH2 and SH3 domains reflect possible mechanisms of recruitment and activation of downstream molecules | Q30176764 | ||
| LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck | Q30193253 | ||
| Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. | Q30193575 | ||
| A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK | Q30448354 | ||
| A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation | Q30491549 | ||
| Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling | Q30633083 | ||
| The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton. | Q31673052 | ||
| Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells | Q33292526 | ||
| Overexpression of the Wiskott-Aldrich syndrome protein N-terminal domain in transgenic mice inhibits T cell proliferative responses via TCR signaling without affecting cytoskeletal rearrangements | Q33339207 | ||
| Linking cellular activation to cytoskeletal reorganization: Wiskott-Aldrich syndrome as a model | Q33342054 | ||
| Functions of gelsolin: motility, signaling, apoptosis, cancer | Q33536511 | ||
| Functional cooperation between the microtubule and actin cytoskeletons | Q33840293 | ||
| Control of actin assembly and disassembly at filament ends | Q33840299 | ||
| A new trigger for T cells | Q34784647 | ||
| WASp in immune-system organization and function | Q34810230 | ||
| Cytoskeletal function in CD8- and T cell receptor-mediated interaction of cytotoxic T lymphocytes with class I protein | Q36229782 | ||
| ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains | Q36266883 | ||
| ZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulation | Q36288209 | ||
| Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells | Q36294111 | ||
| Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions | Q36363083 | ||
| Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways. | Q36370142 | ||
| The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing | Q36401482 | ||
| Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells | Q37384846 | ||
| Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels | Q37397854 | ||
| The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface | Q37419923 | ||
| EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). | Q40716314 | ||
| A role for Wiskott-Aldrich syndrome protein in T-cell receptor-mediated transcriptional activation independent of actin polymerization | Q40815589 | ||
| Differential clustering of CD4 and CD3zeta during T cell recognition | Q40859028 | ||
| Prevention of antigen-induced microtubule organizing center reorientation in cytotoxic T cells by modulation of protein kinase C activity. | Q40989447 | ||
| Polarity of T cell shape, motility, and sensitivity to antigen | Q41202887 | ||
| Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells | Q41398483 | ||
| Rab27a is required for regulated secretion in cytotoxic T lymphocytes | Q42947316 | ||
| Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. | Q43566798 | ||
| Coupling of the TCR to integrin activation by Slap-130/Fyb. | Q43744923 | ||
| Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells. | Q43812081 | ||
| F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts. | Q43867810 | ||
| Regulation of Lck activity by CD4 and CD28 in the immunological synapse | Q43877164 | ||
| Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells | Q43930610 | ||
| How Rab proteins link motors to membranes | Q43954668 | ||
| Characterization and expression analyses of the mouse Wiskott-Aldrich syndrome protein (WASP) family member Wave1/Scar | Q44026573 | ||
| Expression and function of the Eph A receptors and their ligands ephrins A in the rat thymus | Q44037117 | ||
| Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation | Q44066636 | ||
| Interaction of cortactin and N-WASp with Arp2/3 complex | Q44101124 | ||
| Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis | Q46458035 | ||
| Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction | Q46517603 | ||
| Optic flow: A brain region devoted to optic flow analysis? | Q48409799 | ||
| Immunology. Agrin--a bridge between the nervous and immune systems. | Q52019796 | ||
| Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. | Q52124332 | ||
| Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1. | Q52124627 | ||
| Nocodazole inhibits signal transduction by the T cell antigen receptor. | Q52530577 | ||
| Tumor suppressor PTEN mediates sensing of chemoattractant gradients. | Q52546351 | ||
| The immunological synapse of CTL contains a secretory domain and membrane bridges. | Q53676857 | ||
| CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. | Q54260849 | ||
| Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner | Q54966421 | ||
| LAT, the Linker for Activation of T Cells: A Bridge Between T Cell-Specific and General Signaling Pathways | Q56551925 | ||
| Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap | Q57185247 | ||
| A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response | Q57218726 | ||
| Shmoos, Rafts, and Uropods— The Many Facets of Cell Polarity | Q57363719 | ||
| Cell motility: Braking WAVEs | Q57909990 | ||
| Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition | Q57962311 | ||
| How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures | Q33840324 | ||
| Actin machinery: pushing the envelope. | Q33840347 | ||
| Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition | Q33867251 | ||
| Searching for significance in TCR-cytoskeleton interactions | Q33899285 | ||
| A homochiral metal-organic porous material for enantioselective separation and catalysis | Q33901022 | ||
| Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells | Q33947946 | ||
| Mechanism of actin-based motility. | Q33948744 | ||
| The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. | Q33958592 | ||
| WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development | Q34012902 | ||
| Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction | Q34073378 | ||
| Signaling takes shape in the immune system | Q34073408 | ||
| Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins | Q34115639 | ||
| EVH1 domains: structure, function and interactions | Q34120295 | ||
| WH2 domain: a small, versatile adapter for actin monomers. | Q34120315 | ||
| Secrets of actin-based motility revealed by a bacterial pathogen | Q34186304 | ||
| Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42 | Q34284892 | ||
| Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65. | Q34419552 | ||
| The Arp2/3 complex: a central regulator of the actin cytoskeleton | Q34437783 | ||
| Rho family proteins: coordinating cell responses | Q34446303 | ||
| FERMing up the synapse. | Q34453049 | ||
| Dynamics of the immunological synapse: finding, establishing and solidifying a connection | Q34493020 | ||
| Regulation of Wiskott-Aldrich syndrome protein and related molecules | Q34495181 | ||
| Signalling scaffolds and adaptors in T-cell immunity | Q34527641 | ||
| Positive and negative regulation of T-cell activation by adaptor proteins | Q34572179 | ||
| p21-activated kinases: three more join the Pak. | Q34598122 | ||
| Controlling the immune system through semaphorins | Q34611960 | ||
| Formation and function of the immunological synapse | Q34612487 | ||
| Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap | Q34612507 | ||
| PI 3-kinases and PTEN: how opposites chemoattract | Q34682593 | ||
| Cytotoxic T lymphocytes: all roads lead to death | Q34716318 | ||
| VAV proteins as signal integrators for multi-subunit immune-recognition receptors | Q34718119 | ||
| Assembly of the immunological synapse for T cells and NK cells | Q34726206 | ||
| P921 | main subject | cytoskeleton | Q154626 |
| actin | Q185269 | ||
| P304 | page(s) | 220-236 | |
| P577 | publication date | 2003-02-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton | |
| P478 | volume | 191 |
| Q36189418 | A role for the thermal environment in defining co-stimulation requirements for CD4(+) T cell activation |
| Q35216959 | A stochastic view of lymphocyte motility and trafficking within the lymph node |
| Q34522338 | Actin-bundling protein L-plastin regulates T cell activation. |
| Q37639578 | Age-related defects in the cytoskeleton signaling pathways of CD4 T cells |
| Q24299245 | Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules |
| Q24323631 | Cooperative interactions at the SLP-76 complex are critical for actin polymerization |
| Q37298815 | Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation |
| Q63408325 | ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugation |
| Q36438769 | Exploiting pathogenic Escherichia coli to model transmembrane receptor signalling |
| Q36767504 | FOXP3 modifies the phenotypic and functional properties of regulatory T cells |
| Q40370610 | Global transcriptional profiles in peripheral blood mononuclear cell during classical swine fever virus infection |
| Q42990538 | HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse |
| Q57218312 | Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization |
| Q35091278 | Impairment of immunological synapse formation in adaptively tolerant T cells |
| Q34338299 | Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity |
| Q24299345 | Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation |
| Q30157371 | Nck adapter proteins: functional versatility in T cells |
| Q24295390 | Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP |
| Q28239359 | Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis |
| Q30009291 | SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells |
| Q27022243 | T cell antigen recognition at the cell membrane |
| Q40471301 | The Epstein-Barr virus-encoded LMP2A and LMP2B proteins promote epithelial cell spreading and motility. |
| Q37682609 | The Role of SH2 Domain-containing Leukocyte Phosphoprotein of 76 kDa in the Regulation of Immune Cell Development and Function |
| Q26996157 | The actin-bundling protein L-plastin supports T-cell motility and activation |
| Q43149205 | The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling |
| Q40373625 | Tyrosine kinase activity and remodelling of the actin cytoskeleton are co-temporally required for degranulation by cytotoxic T lymphocytes. |
| Q33492741 | Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity |
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