| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1040598008 |
| P356 | DOI | 10.1038/NI848 |
| P698 | PubMed publication ID | 12389042 |
| P5875 | ResearchGate publication ID | 11073013 |
| P50 | author | Doreen Cantrell | Q15994345 |
| P2093 | author name string | Maighread Gallagher | |
| Patrick S Costello | |||
| P2860 | cites work | Spatial and temporal regulation of protein kinase D (PKD) | Q24678757 |
| The immunological synapse: a molecular machine controlling T cell activation | Q28139151 | ||
| T cell receptor signaling precedes immunological synapse formation | Q28203073 | ||
| Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin | Q28208110 | ||
| Three-dimensional segregation of supramolecular activation clusters in T cells | Q28282528 | ||
| Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis | Q28631749 | ||
| Cell cycle and death control: long live Forkheads | Q28646130 | ||
| Spatial sensing in fibroblasts mediated by 3' phosphoinositides | Q30481042 | ||
| Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines | Q31793569 | ||
| From synapses to immunological memory: the role of sustained T cell stimulation | Q33840553 | ||
| Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium | Q33890748 | ||
| Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells | Q33947946 | ||
| PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models. | Q33954288 | ||
| The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. | Q33958592 | ||
| Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction | Q34073378 | ||
| The immunological synapse. | Q34178149 | ||
| Phosphoinositide 3-kinases in T lymphocyte activation | Q34282340 | ||
| The CD28 signaling pathway regulates glucose metabolism | Q34525357 | ||
| Phosphoinositide 3-kinase in immunological systems | Q34555099 | ||
| Protein kinase B (Akt) regulation and function in T lymphocytes | Q34555105 | ||
| Transgenic analysis of thymocyte signal transduction | Q34572219 | ||
| Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells | Q36404256 | ||
| LFA-1-mediated costimulation of CD8+ T cell proliferation requires phosphatidylinositol 3-kinase activity | Q40804976 | ||
| Studies of signal transduction events using chimeras to green fluorescent protein | Q40846784 | ||
| Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction | Q40957062 | ||
| Understanding the mechanisms of sustained signaling and T cell activation | Q41512249 | ||
| The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras | Q42151203 | ||
| The dynamics of protein kinase B regulation during B cell antigen receptor engagement | Q42797373 | ||
| Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways | Q42807426 | ||
| Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen | Q43554100 | ||
| Functional antigen-independent synapses formed between T cells and dendritic cells | Q43740483 | ||
| IL-7 enhances the survival and maintains the size of naive T cells | Q43819910 | ||
| Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module | Q43909644 | ||
| A CD2-green fluorescence protein-transgenic mouse reveals very late antigen-4-dependent CD8+ lymphocyte rolling in inflamed venules | Q44881554 | ||
| The duration of antigenic stimulation determines the fate of naive and effector T cells. | Q51099389 | ||
| The immunological synapse of CTL contains a secretory domain and membrane bridges. | Q53676857 | ||
| Immunology. The immunological synapse--a multitasking system | Q56904592 | ||
| Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens | Q67513113 | ||
| Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice | Q72037334 | ||
| T cell deletion follows chronic antigen specific T cell activation in vivo | Q72674740 | ||
| The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1 | Q73276009 | ||
| Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F | Q73925270 | ||
| Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response | Q74375728 | ||
| The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation | Q77307336 | ||
| Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: dissociation from PKD activation | Q78203645 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | immunology | Q101929 |
| P304 | page(s) | 1082-1089 | |
| P577 | publication date | 2002-10-21 | |
| P1433 | published in | Nature Immunology | Q1071725 |
| P1476 | title | Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse | |
| P478 | volume | 3 |
| Q35111310 | A SLAT in the Th2 Signalosome |
| Q28471992 | A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse |
| Q37021365 | A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse |
| Q38513499 | A septin requirement differentiates autonomous and contact-facilitated T cell proliferation |
| Q28771478 | ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation |
| Q44411064 | AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling |
| Q35662889 | Actin depletion initiates events leading to granule secretion at the immunological synapse |
| Q34014654 | An enigmatic tail of CD28 signaling |
| Q24646010 | An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R |
| Q37322193 | Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse |
| Q34598995 | Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K. |
| Q37283804 | Autocrine regulation of T-cell activation by ATP release and P2X7 receptors |
| Q35612842 | Contact-dependent T cell activation and T cell stopping require talin1 |
| Q46556005 | Continuous T cell receptor signaling required for synapse maintenance and full effector potential |
| Q37774242 | Control systems and decision making for antibody production. |
| Q39040159 | D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes |
| Q37129837 | Determination of T-cell fate by dendritic cells: a new role for asymmetric cell division? |
| Q40540260 | Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen. |
| Q37770429 | Dynamics of dendritic cell-T cell interactions: a role in T cell outcome |
| Q41011213 | Exclusion of exogenous phosphatidylinositol-3,4,5-trisphosphate from neutrophil-polarizing pseudopodia: stabilization of the uropod and cell polarity. |
| Q37321175 | Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells |
| Q53554781 | Global analysis of dynamic changes in lipid raft proteins during T-cell activation. |
| Q58063977 | Immunological synapse formation inhibits, via NF-kappaB and FOXO1, the apoptosis of dendritic cells |
| Q34997154 | In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness |
| Q92463729 | Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma |
| Q35730832 | Jurkat T cells and development of the T-cell receptor signalling paradigm |
| Q37194731 | Lipid-based patterning of the immunological synapse |
| Q39754977 | Measles virus interacts with and alters signal transduction in T-cell lipid rafts |
| Q46015581 | Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. |
| Q38268249 | Metabolic mysteries of the inflammatory response: T cell polarization and plasticity |
| Q37828371 | Metabolism, migration and memory in cytotoxic T cells |
| Q30482179 | Micropatterning of costimulatory ligands enhances CD4+ T cell function |
| Q27026215 | Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse |
| Q41912555 | Murine Tim-1 is excluded from the immunological synapse |
| Q37416272 | New insights into the regulation and function of serine/threonine kinases in T lymphocytes |
| Q46793124 | Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. |
| Q39598751 | OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling |
| Q78704053 | PI3K comes of age |
| Q28187880 | PI3K in lymphocyte development, differentiation and activation |
| Q41367429 | PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans |
| Q42180812 | PI3Kγ kinase activity is required for optimal T-cell activation and differentiation. |
| Q30497801 | PIPKIγ90 Negatively Regulates LFA-1–Mediated Adhesion and Activation in Antigen-Induced CD4+ T Cells |
| Q36601779 | Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+ T Cell Responses during Acute Viral and Intracellular Bacterial Infections |
| Q33800990 | Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking |
| Q41981684 | Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation |
| Q37690383 | Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration |
| Q36229227 | Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation. |
| Q37340915 | Phosphoinositide 3-kinases in cell migration |
| Q27342410 | Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells |
| Q39011409 | Piperine inhibits type II phosphatidylinositol 4-kinases: a key component in phosphoinositides turnover |
| Q46472923 | Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation |
| Q28579464 | Real-time cross-correlation image analysis of early events in IgE receptor signaling |
| Q35145770 | Regulation and function of serine kinase networks in lymphocytes |
| Q38976720 | Regulation of T cell signalling by membrane lipids |
| Q24650027 | Regulation of T-Cell Activation by Phosphodiesterase 4B2 Requires Its Dynamic Redistribution during Immunological Synapse Formation |
| Q37256999 | Regulation of T-cell responses by PTEN |
| Q38034501 | Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases |
| Q38136655 | Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells |
| Q30164809 | SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates |
| Q38241274 | Serine-threonine kinases in TCR signaling. |
| Q52717934 | Signaling and Function of Interleukin-2 in T Lymphocytes. |
| Q39418532 | Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors |
| Q58107689 | Slick signaling |
| Q37403967 | Spatio-temporal dynamics of phosphatidylinositol-3,4,5-trisphosphate signalling. |
| Q42037906 | Stoichiometric quantification of Akt phosphorylation using LC-MS/MS. |
| Q36228047 | T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2 |
| Q29617556 | T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster |
| Q33824896 | T cell signal regulation by the actin cytoskeleton |
| Q37378582 | T-cell activation by dendritic cells in the lymph node: lessons from the movies |
| Q35750980 | T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. |
| Q53595110 | The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. |
| Q38151850 | The actin-driven spatiotemporal organization of T-cell signaling at the system scale |
| Q33734148 | The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. |
| Q36403213 | The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation |
| Q38411250 | The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality |
| Q35166289 | The blood-brain barrier and its role in immune privilege in the central nervous system |
| Q36189959 | The c-SMAC: sorting it all out (or in). |
| Q37855336 | The coordination of T-cell function by serine/threonine kinases |
| Q37585080 | The cunning little vixen: Foxo and the cycle of life and death |
| Q35145749 | The diversity of immunological synapses. |
| Q28186713 | The role of PI3K in immune cells |
| Q34979946 | The significance of OX40 and OX40L to T-cell biology and immune disease. |
| Q85183501 | The space and time frames of T cell activation at the immunological synapse |
| Q41762464 | The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse |
| Q34650772 | Tuning immune responses: diversity and adaptation of the immunological synapse. |
| Q37270444 | Understanding PTEN regulation: PIP2, polarity and protein stability |
| Q28189055 | Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling |
| Q37333623 | Upsides and downsides to polarity and asymmetric cell division in leukemia. |
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