IGSF4 is a novel TCR ζ-chain-interacting protein that enhances TCR-mediated signaling.

scientific article published on 14 November 2011

IGSF4 is a novel TCR ζ-chain-interacting protein that enhances TCR-mediated signaling. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20110853
P932PMC publication ID3256964
P698PubMed publication ID22084409
P5875ResearchGate publication ID51799242

P50authorSin-Hyeog ImQ39923881
Do-Sim ParkQ39964421
P2093author name stringKimi Araki
Ken-ichi Yamamura
Chang-Duk Jun
Hye-Ran Kim
Masatake Araki
Hyun-Su Lee
Suck-Chei Choi
Byeong-Hun Jeon
P2860cites workSHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activationQ22009430
The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chainQ24291295
Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cellsQ24306339
T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membraneQ24319819
Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signalingQ24337208
LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activationQ24672926
The role of membrane-associated adaptors in T cell receptor signallingQ28139105
The immunological synapse: a molecular machine controlling T cell activationQ28139151
Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor DlgQ28185521
IGSF4: a new intercellular adhesion molecule that is called by three names, TSLC1, SgIGSF and SynCAM, by virtue of its diverse functionQ28206998
Identification and functional characterization of the zeta-chain dimerization motif for TCR surface expressionQ73002950
CRTAM: A molecule involved in epithelial cell adhesionQ84428135
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesinQ28208110
LAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysQ28213042
SynCAM, a synaptic adhesion molecule that drives synapse assemblyQ28219424
Three-dimensional segregation of supramolecular activation clusters in T cellsQ28282528
Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesisQ28306927
Regulation of a late phase of T cell polarity and effector functions by CrtamQ28505631
Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5Q28574573
Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptorQ28589506
DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memoryQ30494166
Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.Q30985619
SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF.Q33185273
Disruption of spermatogenic cell adhesion and male infertility in mice lacking TSLC1/IGSF4, an immunoglobulin superfamily cell adhesion moleculeQ34564800
Cellular aspects of early T-cell developmentQ35257634
Transmembrane adaptor proteins: organizers of immunoreceptor signallingQ35852278
Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesisQ36243363
Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cellsQ36350774
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidityQ36401360
Aberrant development of thymocytes in mice lacking laminin-2.Q36511369
The immunological synapse, TCR microclusters, and T cell activationQ37644268
A sequence motif in the transmembrane region of growth factor receptors with tyrosine kinase activity mediates dimerizationQ37878779
Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts.Q40470208
Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemiaQ40506541
Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation.Q40856061
T cell activation pathways: B7, LFA-3, and ICAM-1 shape unique T cell profiles.Q41134187
TCR zeta chain in T cell development and selectionQ41514626
Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivoQ42828727
Integrin functions play a key role in the differentiation of thymocytes in vivoQ43743331
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stagesQ44151375
Stimulation of B lymphocytes through surface Ig receptors induces LFA-1 and ICAM-1-dependent adhesionQ44403661
T cell receptor signallingQ46629952
Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid raftsQ46843999
Spatiotemporal patterns of expression of IGSF4 in developing mouse nervous systemQ48907508
Heterotypic interaction of CRTAM with Necl2 induces cell adhesion on activated NK cells and CD8+ T cellsQ50335827
Regulation of T cell homeostasis by the transmembrane adaptor protein SIT.Q51967862
LAT, the Linker for Activation of T Cells: A Bridge Between T Cell-Specific and General Signaling PathwaysQ56551925
Anomalies d’expression du complexe récepteur T de l’antigène/CD3 et déficits immunitairesQ57078469
Role of ICAM-3 in the initial interaction of T lymphocytes and APCsQ57941405
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2545-2560
P577publication date2011-11-14
P1433published inJournal of Experimental MedicineQ3186912
P1476titleIGSF4 is a novel TCR ζ-chain-interacting protein that enhances TCR-mediated signaling
P478volume208

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cites work (P2860)
Q52308826CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.
Q36455294CRTAM determines the CD4+ cytotoxic T lymphocyte lineage.
Q90731506Change of Immunoglobulin Superfamily Member 4 Gene Expression in the Digestive System after Swimming Exercise in BALB/c Mice
Q47757848Clinicopathological analysis in PTCL-NOS with CADM1 expression
Q34260059Conformational change in transfer RNA is an early indicator of acute cellular damage
Q38480757Database for exchangeable gene trap clones: pathway and gene ontology analysis of exchangeable gene trap clone mouse lines.
Q35182251Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling
Q28243505IGSF1 deficiency syndrome: A newly uncovered endocrinopathy
Q30363319Redundant Postsynaptic Functions of SynCAMs 1-3 during Synapse Formation.
Q34971695Swiprosin-1 is a novel actin bundling protein that regulates cell spreading and migration
Q34649554Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity
Q26781172The exosomes in tumor immunity

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