review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Emmanuel Lorne | Q57026527 |
P2093 | author name string | Edward Abraham | |
Hervé Dupont | |||
P2860 | cites work | MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 | Q22009943 |
I kappa B: a specific inhibitor of the NF-kappa B transcription factor | Q24296774 | ||
Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12 | Q24311379 | ||
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway | Q24321840 | ||
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF | Q24672442 | ||
Free radicals in the physiological control of cell function | Q27860480 | ||
Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B | Q28118928 | ||
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation | Q28131815 | ||
HMG-1 as a late mediator of endotoxin lethality in mice | Q28139166 | ||
Molecular chaperones in the cytosol: from nascent chain to folded protein | Q28205903 | ||
High mobility group box 1 protein interacts with multiple Toll-like receptors | Q28280114 | ||
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70 | Q28303344 | ||
Resolution of lung inflammation by CD44 | Q28506254 | ||
Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages | Q28565498 | ||
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE | Q29620722 | ||
Gene therapy with extracellular superoxide dismutase protects conscious rabbits against myocardial infarction | Q30417743 | ||
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury | Q33381642 | ||
Chaperone-mediated protein folding | Q33604624 | ||
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans. | Q33898219 | ||
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney | Q33948196 | ||
Regulation of lung injury and repair by Toll-like receptors and hyaluronan | Q34462186 | ||
Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist | Q34531671 | ||
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways | Q34625047 | ||
Mechanisms of sepsis-induced organ dysfunction | Q34703764 | ||
Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages | Q34722331 | ||
Nitric oxide synthase inhibition as therapy for sepsis: a decade of promise | Q35069190 | ||
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group | Q35093997 | ||
Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion. | Q35109063 | ||
Reversing established sepsis with antagonists of endogenous high-mobility group box 1. | Q35122534 | ||
Redox signaling and the MAP kinase pathways | Q35191234 | ||
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression | Q35679602 | ||
Cytokine function of heat shock proteins | Q35682849 | ||
CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice | Q35748226 | ||
The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction | Q35818842 | ||
TLR4 activation mediates kidney ischemia/reperfusion injury | Q35987574 | ||
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. | Q36376473 | ||
Structure and function of Toll receptors and their ligands | Q36760336 | ||
Mechanisms of HSP72 release. | Q36834704 | ||
Activation of hepatocytes by extracellular heat shock protein 72. | Q36842307 | ||
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events | Q36946570 | ||
Heat shock proteins and immune system | Q37411827 | ||
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model | Q39831611 | ||
NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression | Q39876451 | ||
Inhibitory effects of Lactobacillus plantarum lipoteichoic acid (LTA) on Staphylococcus aureus LTA-induced tumor necrosis factor-alpha production. | Q39965371 | ||
HMGB1 develops enhanced proinflammatory activity by binding to cytokines. | Q40016396 | ||
Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice | Q40056501 | ||
Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes | Q40555496 | ||
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. | Q40751982 | ||
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells | Q40799740 | ||
The extra domain A of fibronectin activates Toll-like receptor 4. | Q40832345 | ||
Xanthine oxidase-derived oxygen radicals increase lung cytokine expression in mice subjected to hemorrhagic shock | Q42278345 | ||
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice | Q43657691 | ||
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury | Q44231448 | ||
Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway | Q44539124 | ||
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44. | Q44781757 | ||
Rho-kinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: effect on hepatocellular NADPH oxidase system | Q45869921 | ||
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. | Q45935599 | ||
Toll-like receptors 4 contribute to endothelial injury and inflammation in hemorrhagic shock in mice | Q46072656 | ||
Serum levels of Hsp 72 measured early after trauma correlate with survival | Q46479365 | ||
Ethanol mimics ligand-mediated activation and endocytosis of IL-1RI/TLR4 receptors via lipid rafts caveolae in astroglial cells. | Q46639175 | ||
Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production. | Q46743982 | ||
Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity | Q46913615 | ||
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice | Q47200145 | ||
Characterization of heme as activator of Toll-like receptor 4. | Q47787071 | ||
Hemorrhage-induced acute lung injury is TLR-4 dependent | Q47794695 | ||
Essential role of MD-2 in LPS responsiveness and TLR4 distribution | Q50109313 | ||
Hemin: levels in experimental subarachnoid hematoma and effects on dissociated vascular smooth-muscle cells. | Q51659384 | ||
Deleterious role of TLR3 during hyperoxia-induced acute lung injury. | Q52589672 | ||
A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. | Q53180447 | ||
Pro-oxidant and cytotoxic effects of circulating heme. | Q53854957 | ||
CD14and Toll-like Receptor Gene Polymorphisms, Country Living, and Asthma in Adults | Q56893552 | ||
Exercise induces hepatosplanchnic release of heat shock protein 72 in humans | Q59326285 | ||
High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis | Q60692915 | ||
Superoxide dismutase and allopurinol improve survival in an animal model of hemorrhagic shock | Q72647033 | ||
Hemorrhage induces rapid in vivo activation of CREB and NF-kappaB in murine intraparenchymal lung mononuclear cells | Q73070923 | ||
Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury | Q73082035 | ||
Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1 | Q73338462 | ||
Reactive oxygen species contribute to epidermal hyaluronan catabolism in human skin organ culture | Q73848985 | ||
Extracellular superoxide dismutase attenuates lung injury after hemorrhage | Q74235992 | ||
HMG-1 as a mediator of acute lung inflammation | Q74279708 | ||
Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein | Q77967451 | ||
Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury | Q79839081 | ||
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction | Q79856753 | ||
Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipids | Q81374584 | ||
P433 | issue | 11 | |
P921 | main subject | sepsis | Q183134 |
toll-like receptor | Q408004 | ||
P304 | page(s) | 1826-1835 | |
P577 | publication date | 2010-08-06 | |
P1433 | published in | Intensive Care Medicine | Q15749164 |
P1476 | title | Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine? | |
P478 | volume | 36 |
Q42675815 | Advanced glycation end products and lipopolysaccharides stimulate interleukin-6 secretion via the RAGE/TLR4-NF-κB-ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages |
Q36570882 | An endothelial TLR4-VEGFR2 pathway mediates lung protection against oxidant-induced injury |
Q34766423 | Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol. |
Q48027735 | Arterial stiffness, cognitive impairment and dementia: confounding factor or real risk? |
Q36084261 | Autoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophages |
Q35141491 | Burn-induced alterations in toll-like receptor-mediated responses by bronchoalveolar lavage cells |
Q42370317 | Cardiopulmonary bypass in the newborn: effects of circulatory cell-free hemoglobin and hyperoxia evaluated in a novel rat pup model |
Q54366716 | Colistin dampens fibrinolysis and endothelial activation during endotoxaemia. A randomised, double blind trial. |
Q27025519 | Controversial role of toll-like receptors in acute pancreatitis |
Q85798839 | Cytoprotection of perfluorocarbon on PMVECs in vitro |
Q40620094 | Differences in lipopolysaccharide- and lipoteichoic acid-induced cytokine/chemokine expression |
Q41180543 | Effect of pulse high-volume hemofiltration on Toll-like receptor in patients with severe sepsis |
Q64054799 | Emodin alleviates myocardial ischemia/reperfusion injury by inhibiting gasdermin D-mediated pyroptosis in cardiomyocytes |
Q93042234 | Epigallocatechin-3-gallate ameliorates lipopolysaccharide-induced acute lung injury by suppression of TLR4/NF-κB signaling activation |
Q42324501 | Ethanol exposure suppresses bone marrow-derived dendritic cell inflammatory responses independent of TLR4 expression |
Q37825717 | Heat shock proteins and high mobility group box 1 protein lack cytokine function |
Q54783708 | Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats. |
Q39227463 | Immunomodulatory effects of heat-killed Enterococcus faecalis TH10 on murine macrophage cells |
Q27306134 | Impact of Toll-like receptor 2 deficiency on survival and neurological function after cardiac arrest: a murine model of cardiopulmonary resuscitation |
Q38534568 | In vivo porcine lipopolysaccharide inflammation models to study immunomodulation of drugs |
Q37633380 | Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy. |
Q50900704 | Inhibition of reactive oxygen species generation attenuates TLR4-mediated proinflammatory and proliferative phenotype of vascular smooth muscle cells. |
Q37088166 | Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation |
Q35009719 | Lactobacilli and bifidobacteria promote immune homeostasis by modulating innate immune responses to human rotavirus in neonatal gnotobiotic pigs |
Q91828816 | MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1 |
Q36736059 | Microglial CD14 activated by iNOS contributes to neuroinflammation in cerebral ischemia |
Q46574289 | Nandrolone decanoate and resistance exercise training favor the occurrence of lesions and activate the inflammatory response in the ventral prostate. |
Q36426181 | Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4. |
Q54213488 | Pathophysiology and Genetics of Bronchiectasis Unrelated to Cystic Fibrosis. |
Q26770944 | Protracted Oxidative Alterations in the Mechanism of Hematopoietic Acute Radiation Syndrome |
Q38168903 | Recent progress concerning CpG DNA and its use as a vaccine adjuvant |
Q37370570 | Superoxide induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-dependent mechanism |
Q38172423 | TLR2 and TLR4 in autoimmune diseases: a comprehensive review |
Q35278766 | The First Type III Domain of Fibronectin is Associated with the Expression of Cytokines within the Lung Tumor Microenvironment |
Q27022093 | The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells |
Q36079930 | The role of dexamethasone in scorpion venom-induced deregulation of sodium and water transport in rat lungs. |
Q38033199 | The role of heat shock protein 90 in modulating ischemia-reperfusion injury in the kidney. |
Q39772015 | Tlr2 on Bone Marrow and Non-Bone Marrow Derived Cells Regulates Inflammation and Organ Injury in Cooperation with Tlr4 During Resuscitated Hemorrhagic Shock |
Q38994898 | Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles |
Q34534501 | Year in review in Intensive Care Medicine 2010: I. Acute renal failure, outcome, risk assessment and ICU performance, sepsis, neuro intensive care and experimentals |
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