Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

scientific article

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00134-010-1983-5
P932PMC publication ID3090256
P698PubMed publication ID20689929
P5875ResearchGate publication ID45509309

P50authorEmmanuel LorneQ57026527
P2093author name stringEdward Abraham
Hervé Dupont
P2860cites workMD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4Q22009943
I kappa B: a specific inhibitor of the NF-kappa B transcription factorQ24296774
Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12Q24311379
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathwayQ24321840
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIFQ24672442
Free radicals in the physiological control of cell functionQ27860480
Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa BQ28118928
Release of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
HMG-1 as a late mediator of endotoxin lethality in miceQ28139166
Molecular chaperones in the cytosol: from nascent chain to folded proteinQ28205903
High mobility group box 1 protein interacts with multiple Toll-like receptorsQ28280114
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70Q28303344
Resolution of lung inflammation by CD44Q28506254
Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophagesQ28565498
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
Gene therapy with extracellular superoxide dismutase protects conscious rabbits against myocardial infarctionQ30417743
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injuryQ33381642
Chaperone-mediated protein foldingQ33604624
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans.Q33898219
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidneyQ33948196
Regulation of lung injury and repair by Toll-like receptors and hyaluronanQ34462186
Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonistQ34531671
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathwaysQ34625047
Mechanisms of sepsis-induced organ dysfunctionQ34703764
Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophagesQ34722331
Nitric oxide synthase inhibition as therapy for sepsis: a decade of promiseQ35069190
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working groupQ35093997
Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion.Q35109063
Reversing established sepsis with antagonists of endogenous high-mobility group box 1.Q35122534
Redox signaling and the MAP kinase pathwaysQ35191234
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expressionQ35679602
Cytokine function of heat shock proteinsQ35682849
CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in miceQ35748226
The expanding family of MyD88-like adaptors in Toll-like receptor signal transductionQ35818842
TLR4 activation mediates kidney ischemia/reperfusion injuryQ35987574
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.Q36376473
Structure and function of Toll receptors and their ligandsQ36760336
Mechanisms of HSP72 release.Q36834704
Activation of hepatocytes by extracellular heat shock protein 72.Q36842307
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory eventsQ36946570
Heat shock proteins and immune systemQ37411827
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis modelQ39831611
NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expressionQ39876451
Inhibitory effects of Lactobacillus plantarum lipoteichoic acid (LTA) on Staphylococcus aureus LTA-induced tumor necrosis factor-alpha production.Q39965371
HMGB1 develops enhanced proinflammatory activity by binding to cytokines.Q40016396
Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy miceQ40056501
Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromesQ40555496
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.Q40751982
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cellsQ40799740
The extra domain A of fibronectin activates Toll-like receptor 4.Q40832345
Xanthine oxidase-derived oxygen radicals increase lung cytokine expression in mice subjected to hemorrhagic shockQ42278345
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in miceQ43657691
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injuryQ44231448
Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathwayQ44539124
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.Q44781757
Rho-kinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: effect on hepatocellular NADPH oxidase systemQ45869921
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.Q45935599
Toll-like receptors 4 contribute to endothelial injury and inflammation in hemorrhagic shock in miceQ46072656
Serum levels of Hsp 72 measured early after trauma correlate with survivalQ46479365
Ethanol mimics ligand-mediated activation and endocytosis of IL-1RI/TLR4 receptors via lipid rafts caveolae in astroglial cells.Q46639175
Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production.Q46743982
Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicityQ46913615
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient miceQ47200145
Characterization of heme as activator of Toll-like receptor 4.Q47787071
Hemorrhage-induced acute lung injury is TLR-4 dependentQ47794695
Essential role of MD-2 in LPS responsiveness and TLR4 distributionQ50109313
Hemin: levels in experimental subarachnoid hematoma and effects on dissociated vascular smooth-muscle cells.Q51659384
Deleterious role of TLR3 during hyperoxia-induced acute lung injury.Q52589672
A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.Q53180447
Pro-oxidant and cytotoxic effects of circulating heme.Q53854957
CD14and Toll-like Receptor Gene Polymorphisms, Country Living, and Asthma in AdultsQ56893552
Exercise induces hepatosplanchnic release of heat shock protein 72 in humansQ59326285
High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritisQ60692915
Superoxide dismutase and allopurinol improve survival in an animal model of hemorrhagic shockQ72647033
Hemorrhage induces rapid in vivo activation of CREB and NF-kappaB in murine intraparenchymal lung mononuclear cellsQ73070923
Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injuryQ73082035
Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1Q73338462
Reactive oxygen species contribute to epidermal hyaluronan catabolism in human skin organ cultureQ73848985
Extracellular superoxide dismutase attenuates lung injury after hemorrhageQ74235992
HMG-1 as a mediator of acute lung inflammationQ74279708
Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding proteinQ77967451
Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injuryQ79839081
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunctionQ79856753
Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipidsQ81374584
P433issue11
P921main subjectsepsisQ183134
toll-like receptorQ408004
P304page(s)1826-1835
P577publication date2010-08-06
P1433published inIntensive Care MedicineQ15749164
P1476titleToll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?
P478volume36

Reverse relations

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