BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity.

scientific article

BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JNC.12926
P932PMC publication ID4296578
P698PubMed publication ID25099302

P50authorAaron B. BowmanQ37830327
Terry Jo V. BichellQ60227483
P2093author name stringTomás R Guilarte
Kirstie H Stansfield
P2860cites workHeterogeneity and diversity of striatal GABAergic interneuronsQ21090474
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neuronsQ24311721
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Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primatesQ28397442
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubulesQ28590634
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Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates.Q30498692
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Molecular effects of dopamine on striatal-projection pathwaysQ33923086
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Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.Q34071987
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Identification of synaptic terminals of thalamic or cortical origin in contact with distinct medium-size spiny neurons in the rat neostriatumQ36449606
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Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brainQ37303866
Oxidative damage and neurodegeneration in manganese-induced neurotoxicityQ37377815
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Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposureQ39785057
Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.Q39943159
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.Q40519742
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonismQ41951153
Effects of chronic manganese exposure on working memory in non-human primatesQ42057558
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganeseQ42070989
Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brainQ42447105
Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behaviorQ42474126
Effects of chronic manganese exposure on cognitive and motor functioning in non-human primatesQ42746345
Secondary progressive chronic manganism associated with markedly decreased striatal D2 receptor densityQ44285786
Basal Ganglia accumulation and motor assessment following manganese chloride exposure in the C57BL/6 mouseQ44916322
Dopamine D2 Receptor Imaging with SPECT: Studies in Different Neuropsychiatric DisordersQ45292482
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.Q45293425
Cellular localization of huntingtin in striatal and cortical neurons in rats: lack of correlation with neuronal vulnerability in Huntington's disease.Q45297243
Brain energy metabolism and dopaminergic function in Huntington's disease measured in vivo using positron emission tomographyQ45299145
Abnormal motor function and the expression of striatal dopamine D2 receptors in manganese-treated miceQ46338442
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channelsQ48203997
Rat hippocampal neurons in dispersed cell cultureQ48292684
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growthQ48320909
Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI studyQ48422793
Nigrostriatal dopamine system dysfunction and subtle motor deficits in manganese-exposed non-human primatesQ48440122
Anterograde transport of brain-derived neurotrophic factor and its role in the brainQ48539947
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleusQ48691482
The site of termination of afferent fibres in the caudate nucleus.Q51120863
Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.Q64860249
Cognitive function and plasma BDNF levels among manganese-exposed smeltersQ87082201
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectstriatumQ1319792
neurotoxicityQ3338704
P1104number of pages12
P304page(s)655-666
P577publication date2014-09-02
P1433published inJournal of NeurochemistryQ6295643
P1476titleBDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity
P478volume131

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cites work (P2860)
Q28067566"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"
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Q64269538Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus
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Q38479949Manganese Is Essential for Neuronal Health
Q46309597Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders
Q36986770Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice
Q88175593Subchronic Manganese Exposure Impairs Neurogenesis in the Adult Rat Hippocampus