The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility

scientific article

The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1012147096
P356DOI10.1186/1477-7827-12-111
P932PMC publication ID4297407
P698PubMed publication ID25421171
P5875ResearchGate publication ID268880933

P50authorHeide SchattenQ87470672
P2093author name stringQing-Yuan Sun
Randall Prather
P2860cites workManipulating mitochondrial genomes in the clinic: playing by different rulesQ38200226
Maternal diabetes mellitus and the origin of non-communicable diseases in offspring: the role of epigeneticsQ38211819
Oogenesis in cultures derived from adult human ovariesQ21245561
Isolation of small SSEA-4-positive putative stem cells from the ovarian surface epithelium of adult human ovaries by two different methodsQ21284790
Ancient Invasions: From Endosymbionts to OrganellesQ22065818
Degradation of paternal mitochondria after fertilization: implications for heteroplasmy, assisted reproductive technologies and mtDNA inheritanceQ24273113
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's diseaseQ24339508
Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA diseaseQ24607578
Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age womenQ24621872
Origin of germ cells and formation of new primary follicles in adult human ovariesQ24791995
Sequence and organization of the human mitochondrial genomeQ27860659
Cell death: critical control pointsQ28240722
The mitochondrial permeability transition pore and its role in cell deathQ29614183
To err (meiotically) is human: the genesis of human aneuploidyQ29618613
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in miceQ29619811
Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewalQ30501000
Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovariesQ30523980
Maternal diabetes causes abnormal dynamic changes of endoplasmic reticulum during mouse oocyte maturation and early embryo development.Q30539215
Translocation of active mitochondria during pig oocyte maturation, fertilization and early embryo development in vitroQ30993829
Glycolysis in preimplantation development is partially controlled by the Warburg Effect.Q50504958
mtDNA point mutations are present at various levels of heteroplasmy in human oocytes.Q50639726
Low oocyte mitochondrial DNA content in ovarian insufficiency.Q50667877
Mitochondrial DNA content affects the fertilizability of human oocytes.Q50715899
Characterization of polo-like kinase 1 during meiotic maturation of the mouse oocyte.Q50719745
Quantification of mtDNA in single oocytes, polar bodies and subcellular components by real-time rapid cycle fluorescence monitored PCR.Q50722936
Impaired Mitochondrial Function in the Preimplantation Embryo Perturbs Fetal and Placental Development in the Mouse1Q51895745
Mitochondrial DNA copy number in bovine oocytes and somatic cellsQ67255887
Purification and identification of subunit structure of the human mitochondrial DNA polymeraseQ68085274
Ultrastructural and molecular distinctions between the porcine inner cell mass and epiblast reveal unique pluripotent cell statesQ85076076
Regulation of muscle mitochondrial designQ41721498
Mitochondrial behavior during oogenesis in zebrafish: a confocal microscopy analysisQ42696438
Analysis of heterogeneous mitochondria distribution in somatic cell nuclear transfer porcine embryos.Q42808468
The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patientsQ43280587
Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryosQ43594500
Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutationQ43660716
The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidyQ45844850
Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryosQ46138560
Involvement of calcium/calmodulin-dependent protein kinase II (CaMKII) in meiotic maturation and activation of pig oocytesQ46744328
Mitochondria directly influence fertilisation outcome in the pig.Q46923623
Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryosQ47747778
Polar body genome transfer for preventing the transmission of inherited mitochondrial diseasesQ48599871
Medicine. Mitochondrial replacement, evolution, and the clinic.Q48617540
Maternal diabetes causes alterations of DNA methylation statuses of some imprinted genes in murine oocytesQ48628193
Mitochondrial DNA variations in ova and blastocyst: implications in assisted reproductionQ48631865
The importance of mitochondrial metabolic activity and mitochondrial DNA replication during oocyte maturation in vitro on oocyte quality and subsequent embryo developmental competenceQ48651930
Expression of mitochondrial transcription factor A (TFAM) during porcine gametogenesis and preimplantation embryo developmentQ48744475
Remodeling of centrosomes in intraspecies and interspecies nuclear transfer porcine embryosQ48789096
Neutral mitochondrial heteroplasmy alters physiological function in miceQ48790844
Quantification of human ooplasmic mitochondriaQ48829957
Genetics of oocyte ageingQ48925964
Diazepam induces meiotic delay, aneuploidy and predivision of homologues and chromatids in mammalian oocytesQ48926168
Ooplasmic transfer in mature human oocytesQ48942391
Why is chromosome segregation error in oocytes increased with maternal aging?Q37947557
Prevention of mitochondrial disease inheritance by assisted reproductive technologies: prospects and challengesQ37956461
Mitochondrial quality control: a matter of life and death for neuronsQ37987023
Factors influencing the biochemical markers for predicting mammalian oocyte qualityQ38043381
The mitochondrial permeability transition pore: a mystery solved?Q38106976
The root of reduced fertility in aged women and possible therapentic options: current status and future perspects.Q38116677
Preventing the transmission of mitochondrial DNA disorders: selecting the good guys or kicking out the bad guysQ38153518
Sperm mitochondria in reproduction: good or bad and where do they go?Q38163134
Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competenceQ31832630
Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotesQ33559715
DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functionsQ33665573
Portrait of an oocyte: our obscure originQ33755398
MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.Q33763053
Oocyte cytoplasm transfers and the ethics of germ-line interventionQ34077783
Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cellsQ34104122
Mitochondrial shape changes: orchestrating cell pathophysiology.Q34106103
Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENsQ34127971
Therapeutic prospects for mitochondrial diseaseQ34205124
Maternal insulin resistance causes oxidative stress and mitochondrial dysfunction in mouse oocytesQ34272653
Germline stem cells and follicular renewal in the postnatal mammalian ovaryQ34304906
Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapyQ34312609
Whole transcriptome analysis of the effects of type I diabetes on mouse oocytesQ34388271
Three-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseasesQ34395166
Potential impact of human mitochondrial replacement on global policy regarding germline gene modification.Q34420174
Paternal diet-induced obesity retards early mouse embryo development, mitochondrial activity and pregnancy healthQ34540544
Prevalence of mitochondrial DNA disease in adultsQ34691723
Production of offspring from a germline stem cell line derived from neonatal ovariesQ34975362
Ooplasmic transfer: animal models assist human studiesQ35019166
The challenges of mitochondrial replacement.Q35156793
The impact of obesity on egg qualityQ35171112
The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation.Q35218361
The mitochondrial proteome: a dynamic functional program in tissues and disease statesQ35532033
The regulation of oocyte maturationQ35622960
Interplay between mitochondria and cellular calcium signallingQ35672374
Mitochondrial distribution and microtubule organization in fertilized and cloned porcine embryos: implications for developmental potential.Q35751689
Meiotic origins of maternal age-related aneuploidyQ35855863
Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competenceQ35873188
Detection of a specific mitochondrial DNA deletion in tissues of older humansQ35891834
A role for the Warburg effect in preimplantation embryo development: metabolic modification to support rapid cell proliferationQ35894851
Biogenesis of the cytochrome bc(1) complex and role of assembly factors.Q36005582
Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisationQ36035686
The significance of mitochondria for embryo development in cloned farm animalsQ36252700
Mitochondria transfer can enhance the murine embryo developmentQ36268938
Effect of maternal age on the frequency of cytogenetic abnormalities in human oocytesQ36271536
Contribution of the oocyte to embryo qualityQ36300222
Cytoskeleton and cell cycle control during meiotic maturation of the mouse oocyte: integrating time and space.Q36328656
Intrauterine programming of physiological systems: causes and consequencesQ36380587
Potential new strategies for the treatment of ovarian infertility and degenerative diseases with autologous ovarian stem cells.Q36425926
Regulation of oocyte mitochondrial DNA copy number by follicular fluid, EGF, and neuregulin 1 during in vitro maturation affects embryo development in pigsQ36466422
Mitochondrial DNA mutations in human colonic crypt stem cellsQ36524727
Mitochondria and cancer: is there a morphological connection?Q36557994
Polarization of mitochondria in the unfertilized mouse oocyteQ36678554
Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5.Q36727037
Evaluation of oocyte quality: morphological, cellular and molecular predictorsQ36772027
Morphologic and histologic comparisons between in vivo and nuclear transfer derived porcine embryos.Q36796541
Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging.Q36803297
Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase.Q36834600
Mitochondrial function in diabetes: novel methodology and new insightQ36867599
The role of mitochondria from mature oocyte to viable blastocystQ36899560
Functions and dysfunctions of mitochondrial dynamicsQ36967747
Unique insights into maternal mitochondrial inheritance in miceQ37088681
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissuesQ37147048
ART failure: oocyte contributions to unsuccessful fertilizationQ37208094
Maternal diabetes and oocyte qualityQ37265976
A differential autophagic response to hyperglycemia in the developing murine embryoQ37318654
Maternal diabetes causes mitochondrial dysfunction and meiotic defects in murine oocytesQ37369790
Immune physiology and oogenesis in fetal and adult humans, ovarian infertility, and totipotency of adult ovarian stem cells.Q37420642
Oocyte aging: cellular and molecular changes, developmental potential and reversal possibilityQ37476388
The pivotal role of glucose metabolism in determining oocyte developmental competence.Q37678732
Somatic mitochondrial DNA mutations in mammalian agingQ37720726
Clinical and ethical implications of mitochondrial gene transferQ37733738
Age related changes in mitochondrial function and new approaches to study redox regulation in mammalian oocytes in response to age or maturation conditionsQ37785306
Therapeutic treatments of mtDNA diseases at the earliest stages of human developmentQ37819346
Ovarian pluripotent/multipotent stem cells and in vitro oogenesis in mammalsQ37892466
Ovarian stem cell niche and follicular renewal in mammalsQ37895627
Centrosome dynamics during mammalian oocyte maturation with a focus on meiotic spindle formationQ37925679
New insights into the role of centrosomes in mammalian fertilization and implications for ART.Q37930810
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P921main subjectcellQ7868
nuclear transferQ3997715
genitourinary systemQ4712977
biomedical investigative techniqueQ66648976
P304page(s)111
P577publication date2014-11-24
P1433published inReproductive Biology and EndocrinologyQ15767218
P1476titleThe impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility
P478volume12

Reverse relations

cites work (P2860)
Q64230353Advanced Maternal Age in IVF: Still a Challenge? The Present and the Future of Its Treatment
Q89874257Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality
Q91672405Autologous mitochondrial microinjection; a strategy to improve the oocyte quality and subsequent reproductive outcome during aging
Q92515439Comprehensive mitochondrial DNA analysis and IVF outcome
Q33826775Cumulus cell mitochondrial activity in relation to body mass index in women undergoing assisted reproductive therapy
Q42778111Differing molecular response of young and advanced maternal age human oocytes to IVM.
Q89509143Effect of Melatonin on the In Vitro Maturation of Porcine Oocytes, Development of Parthenogenetically Activated Embryos, and Expression of Genes Related to the Oocyte Developmental Capability
Q41244925Ginsenoside Rb1 improves cardiac function and remodeling in heart failure
Q39440437Laboratory tests for oxidative stress.
Q37526318Lack of calcium oscillation causes failure of oocyte activation after intracytoplasmic sperm injection in pigs
Q46514239Methoxychlor exposure induces oxidative stress and affects mouse oocyte meiotic maturation
Q33815005MicroRNA-130b is involved in bovine granulosa and cumulus cells function, oocyte maturation and blastocyst formation
Q92964663Mid-life fertility: Challenges & policy planning
Q89640447Mitochondria: the panacea to improve oocyte quality?
Q37729935Mitochondrial Modification Techniques and Ethical Issues
Q48047379Mitochondrial dysfunction and ovarian aging.
Q57952489Mitochondrial manipulation in fertility clinics: Regulation and responsibility
Q89386631Mitochondrial regulation of [Ca2+]i oscillations during cell cycle resumption of the second meiosis of oocyte
Q30645234Novel methods of treating ovarian infertility in older and POF women, testicular infertility, and other human functional diseases
Q38708531Novel reproductive technologies to prevent mitochondrial disease
Q38827762Ovarian ageing: the role of mitochondria in oocytes and follicles.
Q38851128Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics
Q64059886Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells
Q39302086Role of Antioxidants in Assisted Reproductive Techniques
Q48507390Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes
Q88914451The Effects of Sodium Selenite on Mitochondrial DNA Copy Number and Reactive Oxygen Species Levels of In Vitro Matured Mouse Oocytes
Q47582338The futile case of the aging ovary: is it mission impossible? A focused review
Q27342890The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes
Q90451040The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation
Q64083443Transcriptome analysis of egg viability in rainbow trout, Oncorhynchus mykiss
Q40979055Transcriptome meta-analysis of three follicular compartments and its correlation with ovarian follicle maturity and oocyte developmental competence in cows.
Q48504865Transfer of autologous mitochondria from adipose tissue-derived stem cells rescues oocyte quality and infertility in aged mice

Search more.