Why is chromosome segregation error in oocytes increased with maternal aging?

scientific article published on October 2011

Why is chromosome segregation error in oocytes increased with maternal aging? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/PHYSIOL.00020.2011
P698PubMed publication ID22013190

P50authorHeide SchattenQ87470672
P2093author name stringQing-Yuan Sun
Zhen-Bo Wang
P2860cites workMaternal age-related differential global expression profiles observed in human oocytesQ48789155
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Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitroQ45061653
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Increasing age influences uterine integrity, but not ovarian function or oocyte quality, in the cheetah (Acinonyx jubatus).Q48673434
Increased zona pellucida thickness and meiotic spindle disruption in oocytes from cigarette smoking mice.Q48683422
Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint.Q48725350
Defective cohesin is associated with age-dependent misaligned chromosomes in oocytesQ48765831
Continuous exposure to bisphenol A during in vitro follicular development induces meiotic abnormalitiesQ48770023
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Oocyte Cohesin Expression Restricted to Predictyate Stages Provides Full Fertility and Prevents AneuploidyQ34153758
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Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytesQ34289002
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Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errorsQ35576326
New insights into the genetic regulation of homologue disjunction in mammalian oocytes.Q35576437
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SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombinationQ36117975
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Age-associated increase in aneuploidy and changes in gene expression in mouse eggsQ36642995
Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids during mouse oocyte meiosisQ36938393
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Meiosis in oocytes: predisposition to aneuploidy and its increased incidence with age.Q37033768
Human female meiosis: what makes a good egg go bad?Q37055902
Heterochromatin-mediated association of achiasmate homologs declines with age when cohesion is compromisedQ37152661
Faulty spindle checkpoint and cohesion protein activities predispose oocytes to premature chromosome separation and aneuploidyQ37216524
Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice.Q37293388
Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggsQ37369753
Cohesin SMC1beta protects telomeres in meiocytesQ37402354
Oocyte aging: cellular and molecular changes, developmental potential and reversal possibilityQ37476388
P433issue5
P304page(s)314-325
P577publication date2011-10-01
P1433published inPhysiologyQ1091804
P1476titleWhy is chromosome segregation error in oocytes increased with maternal aging?
P478volume26

Reverse relations

cites work (P2860)
Q33784903Arrested human embryos are more likely to have abnormal chromosomes than developing embryos from women of advanced maternal age.
Q41605192DNA microarray reveals that high proportions of human blastocysts from women of advanced maternal age are aneuploid and mosaic
Q38038996Epigenetic changes associated with oocyte aging
Q90655817Functions and dysfunctions of the mammalian centrosome in health, disorders, disease, and aging
Q35938140Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey
Q36235524Lack of response to unaligned chromosomes in mammalian female gametes
Q39612655Oocyte-specific deletion of N-WASP does not affect oocyte polarity, but causes failure of meiosis II completion.
Q38282802Polar bodies in assisted reproductive technology: current progress and future perspectives
Q38915548Predictive value of spindle retardance in embryo implantation rate
Q33953122Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.
Q34979054The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility
Q37445023The prevalence of chromosomal deletions relating to developmental delay and/or intellectual disability in human euploid blastocysts
Q48504865Transfer of autologous mitochondria from adipose tissue-derived stem cells rescues oocyte quality and infertility in aged mice

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