MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

scientific article

MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PATH.4363
P932PMC publication ID4298809
P698PubMed publication ID24752803
P5875ResearchGate publication ID261771385

P50authorStefan WiemannQ38155058
Zita SoonsQ54153124
Kirti ShuklaQ57076892
Aleksandra BalwierzQ58329967
P2093author name stringRainer König
Ozgür Sahin
Aoife Ward
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Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cellsQ28216467
Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG studyQ28729855
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Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumoursQ34150301
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Downregulation of miR-342 is associated with tamoxifen resistant breast tumors.Q34506613
High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy.Q34549892
Analysis of apoptosis by propidium iodide staining and flow cytometryQ34615421
Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancerQ34635861
Modelling breast cancer: one size does not fit all.Q34667643
Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancerQ34816422
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancerQ35191588
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Tamoxifen-stimulated growth of breast cancer due to p21 lossQ36423493
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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levelsQ37068662
MicroRNA and drug resistanceQ37751868
Endocrine pharmacology of antiestrogens as antitumor agentsQ38038012
Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancerQ39363790
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cellsQ39618112
miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancerQ39698184
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated regionQ39733975
Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expressionQ40072282
Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancerQ40544950
Signaling pathways of apoptosis activated by aromatase inhibitors and antiestrogensQ40614262
Antiestrogen action in breast cancer cells: modulation of proliferation and protein synthesis, and interaction with estrogen receptors and additional antiestrogen binding sitesQ43685275
Tamoxifen long-term treatment in vitro alters the apoptotic response of MCF-7 breast cancer cellsQ45115291
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.Q51542616
The dark side of a success story: microRNAs of the C19MC cluster in human tumours.Q54526480
microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast CancerQ58211596
Estrogen receptor as an independent prognostic factor for early recurrence in breast cancerQ67710267
Overexpression of HER2 modulates bcl-2, bcl-XL, and tamoxifen-induced apoptosis in human MCF-7 breast cancer cellsQ77557300
P433issue4
P921main subjectbreast cancerQ128581
microRNAQ310899
tamoxifenQ412178
P304page(s)368-379
P577publication date2014-06-02
P1433published inJournal of PathologyQ400296
P1476titleMicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer
P478volume233

Reverse relations

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