scholarly article | Q13442814 |
P819 | ADS bibcode | 2008PNAS..10520297A |
P356 | DOI | 10.1073/PNAS.0809376106 |
P932 | PMC publication ID | 2629338 |
P698 | PubMed publication ID | 19088191 |
P5875 | ResearchGate publication ID | 23669123 |
P50 | author | Kotb Abdelmohsen | Q42681043 |
Subramanya Srikantan | Q56529375 | ||
Yuki Kuwano | Q117285146 | ||
Myriam Gorospe | Q19766141 | ||
P2860 | cites work | ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. | Q39864466 |
HuR: post-transcriptional paths to malignancy. | Q40203356 | ||
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation | Q40749123 | ||
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. | Q42825905 | ||
p16(INK4a) translation suppressed by miR-24 | Q21092220 | ||
The nuclear RNase III Drosha initiates microRNA processing | Q24295234 | ||
Phosphorylation of HuR by Chk2 regulates SIRT1 expression | Q24297993 | ||
Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization | Q24540154 | ||
Oncomirs - microRNAs with a role in cancer | Q27860773 | ||
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA | Q27860813 | ||
MicroRNAs: small RNAs with a big role in gene regulation | Q27860896 | ||
MicroRNAs: genomics, biogenesis, mechanism, and function | Q27861070 | ||
Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA | Q28114829 | ||
Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2 | Q28118240 | ||
From birth to death: the complex lives of eukaryotic mRNAs | Q29615021 | ||
HuR and mRNA stability | Q29615185 | ||
RNA regulons: coordination of post-transcriptional events | Q29618919 | ||
HNS, a nuclear-cytoplasmic shuttling sequence in HuR | Q33579107 | ||
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha | Q33841858 | ||
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence | Q33969339 | ||
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR | Q34563086 | ||
Posttranscriptional orchestration of an anti-apoptotic program by HuR. | Q34632309 | ||
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation | Q35168095 | ||
HuR in the mammalian genotoxic response: post-transcriptional multitasking | Q35215023 | ||
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs | Q36177481 | ||
HuR, an RNA-binding protein, involved in the control of cellular differentiation. | Q36376209 | ||
Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis | Q36404954 | ||
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha | Q36421108 | ||
MicroRNAs in biological processes and carcinogenesis. | Q36617667 | ||
Nuclear HuR accumulation through phosphorylation by Cdk1 | Q36802838 | ||
Identification of a target RNA motif for RNA-binding protein HuR. | Q36853256 | ||
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence | Q37051346 | ||
Getting to the root of miRNA-mediated gene silencing | Q37055551 | ||
P433 | issue | 51 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | RNA-binding proteins | Q3928341 |
P304 | page(s) | 20297-20302 | |
P577 | publication date | 2008-12-16 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels | |
P478 | volume | 105 |
Q34115475 | 7SL RNA represses p53 translation by competing with HuR |
Q85347759 | A biochemical approach to identify direct microRNA targets |
Q34206458 | A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation |
Q38241292 | Aberrant regulation and function of microRNAs in cancer. |
Q41942664 | Activation of the two microRNA clusters C19MC and miR-371-3 does not play prominent role in thyroid cancer |
Q26865703 | Adaptive and maladaptive expression of the mRNA regulatory protein HuR |
Q36819288 | An indirect role for oncomir-519b in the expression of truncated neurokinin-1 in breast cancer cells |
Q34432844 | Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types |
Q34903032 | Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells |
Q52606072 | Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas. |
Q40396217 | Clinical Significance of Hu-Antigen Receptor (HuR) and Cyclooxygenase-2 (COX-2) Expression in Human Malignant and Benign Thyroid Lesions |
Q38238932 | Clinical significance of HuR expression in human malignancy. |
Q35079102 | Coding region: the neglected post-transcriptional code |
Q24635240 | Competitive regulation of nucleolin expression by HuR and miR-494 |
Q49922188 | Complex HuR function in pancreatic cancer cells |
Q28075325 | Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment |
Q33817646 | Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation |
Q38894711 | Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer |
Q37716443 | E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C |
Q38624619 | Elevated Hu-Antigen Receptor (HuR) Expression is Associated with Tumor Aggressiveness and Poor Prognosis but not with COX-2 Expression in Invasive Breast Carcinoma Patients |
Q28393012 | Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs |
Q38384387 | Exploiting a novel miR-519c-HuR-ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer. |
Q58743732 | Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach |
Q37469123 | Factors interacting with HIF-1alpha mRNA: novel therapeutic targets |
Q34002202 | Fragile X protein family member FXR1P is regulated by microRNAs |
Q26865793 | Functional interplay between RNA-binding protein HuR and microRNAs |
Q36210880 | Growth inhibition by miR-519 via multiple p21-inducing pathways |
Q34586591 | HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers |
Q44445934 | Hu-antigen receptor (HuR) and cyclooxygenase-2 (COX-2) expression in human non-small-cell lung carcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients' survival. |
Q35982020 | HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells |
Q37734542 | HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA |
Q38238038 | HuR and post-transcriptional regulation in vascular aging |
Q35966719 | HuR function in disease. |
Q39599360 | HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium |
Q36826825 | HuR maintains a replicative life span by repressing the ARF tumor suppressor. |
Q35844363 | Identification of novel microRNAs in Xenopus laevis metaphase II arrested eggs |
Q35009816 | Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs |
Q36791642 | Induction of VEGFA mRNA translation by CoCl2 mediated by HuR. |
Q26772219 | Inflamma-miRs in Aging and Breast Cancer: Are They Reliable Players? |
Q92316676 | Inhibition of Caspase-2 Translation by the mRNA Binding Protein HuR: A Novel Path of Therapy Resistance in Colon Carcinoma Cells? |
Q92087845 | Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood |
Q44964663 | Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27. |
Q64933852 | Knockdown of MSI1 inhibits the proliferation of human oral squamous cell carcinoma by inactivating STAT3 signaling. |
Q34117694 | Krüppel -like factor 8 is a stress-responsive transcription factor that regulates expression of HuR. |
Q21563369 | Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP |
Q99711727 | Long non-coding RNA HOXA-AS2 promotes the expression levels of hypoxia-inducible factor-1α and programmed death-ligand 1, and regulates nasopharyngeal carcinoma progression via miR-519 |
Q38073445 | Mechanisms coordinating ELAV/Hu mRNA regulons |
Q38000257 | MicroRNA Regulation of SIRT1. |
Q34056462 | MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence |
Q37913018 | MicroRNA regulation by RNA-binding proteins and its implications for cancer |
Q36819807 | MicroRNA-125a represses cell growth by targeting HuR in breast cancer |
Q38544039 | MicroRNA-519 enhances HL60 human acute myeloid leukemia cell line proliferation by reducing the expression level of RNA-binding protein human antigen R. |
Q46617996 | MicroRNA-519a demonstrates significant tumour suppressive activity in laryngeal squamous cells by targeting anti-carcinoma HuR gene |
Q34984068 | MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer |
Q36571466 | MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma |
Q21195211 | MicroRNAs and their target gene networks in breast cancer |
Q38241604 | MicroRNAs as Mediators of the Ageing Process |
Q34594189 | MicroRNAs: Meta-controllers of gene expression in synaptic activity emerge as genetic and diagnostic markers of human disease |
Q35031045 | MicroRegulators come of age in senescence |
Q42549720 | Micromanaging senescence |
Q34860544 | Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation |
Q36590130 | Modulation of cancer traits by tumor suppressor microRNAs |
Q28290458 | Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis |
Q33919479 | Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice. |
Q36234289 | NSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation |
Q26786557 | Noncoding RNA control of cellular senescence |
Q38801218 | Orai1, a Direct Target of microRNA-519, Promotes Progression of Colorectal Cancer via Akt/GSK3β Signaling Pathway |
Q35002018 | Paradoxical microRNAs: individual gene repressors, global translation enhancers |
Q27693879 | Physiological networks and disease functions of RNA-binding protein AUF1 |
Q35087731 | Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs |
Q92802265 | Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins |
Q34065213 | Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements |
Q28117769 | Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cells |
Q36289513 | Posttranscriptional Regulation of the Inflammatory Marker C-Reactive Protein by the RNA-Binding Protein HuR and MicroRNA 637. |
Q28248667 | Posttranscriptional regulation of cancer traits by HuR |
Q37139161 | Principles of miRNA-target regulation in metazoan models |
Q38222976 | RNA binding proteins: a common denominator of neuronal function and dysfunction |
Q38656079 | RNA-Binding Proteins in Cancer: Old Players and New Actors. |
Q24609537 | RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage |
Q33703426 | RNA-binding proteins implicated in the hypoxic response |
Q33719354 | Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence |
Q34078714 | Regulation of HuR by DNA Damage Response Kinases |
Q37231719 | Regulation of SIRT1 by oxidative stress-responsive miRNAs and a systematic approach to identify its role in the endothelium |
Q35188559 | Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines |
Q37617262 | Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment |
Q37961734 | Role of epigenomics in ovarian and endometrial cancers |
Q34365804 | Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells |
Q38232804 | Senescence suppressors: their practical importance in replicative lifespan extension in stem cells |
Q34358827 | Small engine, big power: microRNAs as regulators of cardiac diseases and regeneration. |
Q39168123 | Sphingosine kinase 1 overexpression stimulates intestinal epithelial cell proliferation through increased c-Myc translation |
Q35689148 | Stress granules, P-bodies and cancer. |
Q33704980 | Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR. |
Q24598467 | Temporal and spatial regulation of miR-320 in the uterus during embryo implantation in the rat |
Q98291924 | The RNA-Binding Protein HuR in Digestive System Tumors |
Q35842164 | The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cells |
Q35922433 | The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation |
Q35902777 | The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development. |
Q37930474 | The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins |
Q54526480 | The dark side of a success story: microRNAs of the C19MC cluster in human tumours. |
Q36481823 | The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition |
Q27015587 | The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease |
Q34126704 | Thy-1 mRNA destabilization by norepinephrine a 3' UTR cAMP responsive decay element and involves RNA binding proteins |
Q47103145 | Transcriptional and Post-Transcriptional Mechanisms of the Development of Neocortical Lamination |
Q38285903 | Translational control of TOP2A influences doxorubicin efficacy |
Q50420348 | Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. |
Q33727842 | dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial |
Q34013644 | hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies |
Q38630891 | lnc00673 (ERRLR01) is a Prognostic Indicator of Overall Survival in Breast Cancer. |
Q34528510 | miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression |
Q37148515 | miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration |
Q34534146 | miR-203 regulates cell proliferation through its influence on Hakai expression |
Q64097710 | miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer |
Q34669316 | miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor |
Q28505972 | miR-29b represses intestinal mucosal growth by inhibiting translation of cyclin-dependent kinase 2 |
Q34119806 | miR-375 inhibits differentiation of neurites by lowering HuD levels |
Q34231459 | miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies |
Q92835467 | miR-519 regulates the proliferation of breast cancer cells via targeting human antigen R |
Q41764008 | miR-519 suppresses tumor growth by reducing HuR levels |
Q46294728 | miRNA expressions in rectal cancer as predictors of response to neoadjuvant chemoradiation therapy |
Q94452973 | microRNA-519d Induces Autophagy and Apoptosis of Human Hepatocellular Carcinoma Cells Through Activation of the AMPK Signaling Pathway via Rab10 |
Q27693891 | microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer |
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