scholarly article | Q13442814 |
P50 | author | Epaminondas Doxakis | Q90778883 |
P2093 | author name string | Epaminondas Doxakis | |
P2860 | cites work | Discovery of tissue-specific exons using comprehensive human exon microarrays | Q21092870 |
Neuroligins and neurexins link synaptic function to cognitive disease | Q22251092 | ||
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS | Q24297462 | ||
FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding | Q24311412 | ||
Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system | Q24317395 | ||
The fragile-X premutation: a maturing perspective | Q24533443 | ||
Translational control by neuroguidin, a eukaryotic initiation factor 4E and CPEB binding protein | Q24548966 | ||
A large-scale analysis of mRNA polyadenylation of human and mouse genes | Q24557438 | ||
Stress granule assembly is mediated by prion-like aggregation of TIA-1 | Q24559953 | ||
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability | Q24601827 | ||
RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage | Q24609537 | ||
Patterns of variant polyadenylation signal usage in human genes | Q24624061 | ||
Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function | Q24629019 | ||
Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain | Q24629850 | ||
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import | Q24630100 | ||
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism | Q24631425 | ||
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing | Q24631683 | ||
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS | Q24633692 | ||
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD | Q24634583 | ||
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. | Q24644826 | ||
HITS-CLIP yields genome-wide insights into brain alternative RNA processing | Q24648963 | ||
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites | Q24653978 | ||
Dynamic integration of splicing within gene regulatory pathways | Q26852632 | ||
Functional interplay between RNA-binding protein HuR and microRNAs | Q26865793 | ||
TDP-43-mediated neuron loss in vivo requires RNA-binding activity | Q27321280 | ||
Alternative isoform regulation in human tissue transcriptomes | Q27861118 | ||
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes | Q28114892 | ||
The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein | Q28117885 | ||
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses | Q28118799 | ||
Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome | Q48351859 | ||
Reduced extinction of hippocampal-dependent memories in CPEB knockout mice | Q48665716 | ||
Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons | Q48939998 | ||
A hierarchy of Hu RNA binding proteins in developing and adult neurons | Q52195067 | ||
Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death | Q52537887 | ||
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. | Q52894285 | ||
Hu proteins regulate polyadenylation by blocking sites containing U-rich sequences | Q53586436 | ||
An activity-dependent switch to cap-independent translation triggered by eIF4E dephosphorylation | Q57042159 | ||
Immunological and pathological study of anti-Ri-associated encephalopathy | Q57256469 | ||
Regulation of protein synthesis by mRNA structure | Q57397558 | ||
Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV | Q80546403 | ||
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Q28131672 | ||
The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
Identification of an RNA binding specificity for the potential splicing factor TLS | Q28138875 | ||
Protein misfolding, evolution and disease | Q28143452 | ||
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9 | Q28208568 | ||
Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins | Q28208722 | ||
Protein folding and misfolding | Q28235199 | ||
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis | Q28236796 | ||
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 | Q28236805 | ||
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor | Q28261458 | ||
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping | Q28269954 | ||
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome | Q28273791 | ||
Domain architectures and characterization of an RNA-binding protein, TLS | Q28276007 | ||
Survival motor neuron protein facilitates assembly of stress granules | Q28276466 | ||
Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes | Q28303541 | ||
Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation | Q28304276 | ||
Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation | Q28304355 | ||
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue | Q28475724 | ||
CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA | Q28507871 | ||
A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing | Q28512596 | ||
Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene | Q28513435 | ||
The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia | Q28513858 | ||
Dendritic localization of the RNA-binding protein HuD in hippocampal neurons: association with polysomes and upregulation during contextual learning | Q28564874 | ||
Cytoplasmic polyadenylation element-like sequences are involved in dendritic targeting of BDNF mRNA in hippocampal neurons | Q28564937 | ||
CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses | Q28574713 | ||
Protein kinase C stimulates HuD‐mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture | Q28575286 | ||
Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory | Q28578336 | ||
Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain | Q28583125 | ||
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability | Q28586051 | ||
The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits | Q28588310 | ||
Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules | Q28590022 | ||
mRNA turnover rate limits siRNA and microRNA efficacy | Q28914778 | ||
Signatures of RNA binding proteins globally coupled to effective microRNA target sites | Q28914779 | ||
NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. | Q29347260 | ||
Internal initiation of translation of five dendritically localized neuronal mRNAs | Q34492771 | ||
HuD Promotes BDNF Expression in Brain Neurons via Selective Stabilization of the BDNF Long 3′UTR mRNA | Q34576914 | ||
Anti-Ri: an antibody associated with paraneoplastic opsoclonus and breast cancer. | Q34619192 | ||
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. | Q34982074 | ||
TDP-43 is recruited to stress granules in conditions of oxidative insult. | Q35003958 | ||
Gene structure prediction and alternative splicing analysis using genomically aligned ESTs | Q35032875 | ||
Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling | Q35047447 | ||
Compromised paraspeckle formation as a pathogenic factor in FUSopathies | Q35066217 | ||
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner | Q35202794 | ||
Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus | Q35234990 | ||
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines | Q35399488 | ||
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability | Q35562869 | ||
The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain | Q35746259 | ||
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons | Q35855671 | ||
Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation | Q35860663 | ||
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin | Q35891912 | ||
Function of RNA-binding protein Musashi-1 in stem cells | Q36144910 | ||
ELAV mediates 3' UTR extension in the Drosophila nervous system | Q36331360 | ||
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems | Q36438588 | ||
An alternative mode of microRNA target recognition | Q36522819 | ||
The RNA-binding protein HuD: a regulator of neuronal differentiation, maintenance and plasticity | Q36574657 | ||
Neuronal RNA granules: movers and makers | Q36597037 | ||
RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations | Q36626888 | ||
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs | Q36650975 | ||
Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs | Q36796132 | ||
MicroRNA-125a represses cell growth by targeting HuR in breast cancer | Q36819807 | ||
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons | Q36856173 | ||
Defining a neuron: neuronal ELAV proteins | Q36967781 | ||
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels | Q37068662 | ||
Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing | Q37096623 | ||
Principles of miRNA-target regulation in metazoan models | Q37139161 | ||
Synaptic vesicle protein trafficking at the glutamate synapse. | Q37160079 | ||
Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. | Q37160188 | ||
Diverse molecular functions of Hu proteins | Q37200596 | ||
Pre-mRNA splicing: awash in a sea of proteins | Q29547272 | ||
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing | Q29547470 | ||
Alzheimer's disease is a synaptic failure | Q29547670 | ||
Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels | Q29614781 | ||
RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. | Q30442890 | ||
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. | Q30456334 | ||
A mouse model of the human Fragile X syndrome I304N mutation | Q30484632 | ||
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6 | Q30492839 | ||
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion | Q30532680 | ||
Differential repression of alternative transcripts: a screen for miRNA targets | Q30815465 | ||
Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types | Q33520920 | ||
TDP-43 is a developmentally regulated protein essential for early embryonic development | Q33673895 | ||
The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite | Q33797879 | ||
Splicing factor and exon profiling across human tissues | Q33871191 | ||
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS | Q33889532 | ||
Age-related decline in chaperone-mediated autophagy | Q33901509 | ||
Organization of the human gene encoding heterogeneous nuclear ribonucleoprotein type I (hnRNP I) and characterization of hnRNP I related pseudogene. | Q33920730 | ||
The RNA-binding protein HuD regulates neuronal cell identity and maturation. | Q33934348 | ||
Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins. | Q33944818 | ||
CPEB: a life in translation | Q34003974 | ||
Alternative cleavage and polyadenylation: extent, regulation and function | Q34037217 | ||
Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43. | Q34074385 | ||
N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses | Q34078959 | ||
Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF). | Q34115778 | ||
TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. | Q34131994 | ||
Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression | Q34157806 | ||
Paraneoplastic syndromes associated with anti-Hu antibodies | Q34246190 | ||
Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling | Q34250045 | ||
The neurobiology of the opsoclonus-myoclonus syndrome | Q34253108 | ||
Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies | Q34281671 | ||
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules | Q34308339 | ||
A conserved family of elav-like genes in vertebrates | Q34344417 | ||
G-quartet-dependent recognition between the FMRP RGG box and RNA. | Q34365357 | ||
Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation | Q34369092 | ||
miRNA regulons associated with synaptic function | Q34446986 | ||
Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation | Q37235358 | ||
A physical and functional link between splicing factors promotes pre-mRNA 3' end processing | Q37298592 | ||
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity | Q37339064 | ||
A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus | Q37352402 | ||
Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS. | Q37381821 | ||
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs | Q37491595 | ||
Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles | Q37513552 | ||
Prion neurodegeneration: starts and stops at the synapse | Q37627087 | ||
Alternative pre-mRNA splicing in neurons: growing up and extending its reach | Q37649232 | ||
Spatially restricting gene expression by local translation at synapses | Q37715121 | ||
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. | Q37811131 | ||
The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins | Q37930474 | ||
RNA dysregulation in diseases of motor neurons. | Q37950454 | ||
Regulated protein aggregation: stress granules and neurodegeneration | Q38060891 | ||
TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update | Q38096349 | ||
Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction | Q38122142 | ||
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. | Q38341668 | ||
Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm | Q39176818 | ||
ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications | Q39319522 | ||
Specificity of RNA Binding by CPEB: Requirement for RNA Recognition Motifs and a Novel Zinc Finger | Q39574182 | ||
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. | Q39584699 | ||
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade | Q39627495 | ||
A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence. | Q39722557 | ||
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. | Q39761567 | ||
Identification and analysis of the human neural polypyrimidine tract binding protein (nPTB) gene promoter region. | Q40400706 | ||
Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells. | Q40524276 | ||
The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2. | Q40531440 | ||
Polypyrimidine tract binding protein modulates efficiency of polyadenylation. | Q40815645 | ||
A point mutation in the FMR-1 gene associated with fragile X mental retardation | Q41579799 | ||
Absence of expression of the FMR-1 gene in fragile X syndrome | Q41669091 | ||
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain | Q41955381 | ||
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns | Q42146718 | ||
Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions | Q42246467 | ||
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex | Q42255765 | ||
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II. | Q42462537 | ||
Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS). | Q46226347 | ||
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. | Q46409672 | ||
Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function | Q46434717 | ||
Bidirectional regulation of cytoplasmic polyadenylation element-binding protein phosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1 during hippocampal long-term potentiation. | Q46535544 | ||
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior | Q47071494 | ||
Cytoplasmic polyadenylation element binding protein 1-mediated mRNA translation in Purkinje neurons is required for cerebellar long-term depression and motor coordination | Q48136862 | ||
Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD. | Q48329865 | ||
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease | Q48332804 | ||
P433 | issue | 4 | |
P304 | page(s) | 610-626 | |
P577 | publication date | 2014-06-24 | |
P1433 | published in | Neuroscience Bulletin | Q15764540 |
P1476 | title | RNA binding proteins: a common denominator of neuronal function and dysfunction | |
P478 | volume | 30 |
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