In Search of HPA Axis Dysregulation in Child and Adolescent Depression

scientific article published on June 1, 2011

In Search of HPA Axis Dysregulation in Child and Adolescent Depression is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S10567-011-0084-5
P953full work available at URLhttp://www.springerlink.com/index/pdf/10.1007/s10567-011-0084-5
https://europepmc.org/articles/PMC3095794
https://europepmc.org/articles/PMC3095794?pdf=render
https://link.springer.com/content/pdf/10.1007/s10567-011-0084-5.pdf
P932PMC publication ID3095794
P698PubMed publication ID21290178
P5875ResearchGate publication ID49806775

P2093author name stringPaul D. Hastings
John D. Guerry
P2860cites workMolecular PsychiatryQ6895973
Journal of Psychiatry & NeuroscienceQ15814226
A rating scale for depressionQ24564540
The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)Q29547223
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actionsQ29547410
Effects of stress throughout the lifespan on the brain, behaviour and cognitionQ29615801
Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity dataQ29616031
Hypothalamic-pituitary-adrenal axis dysregulation in dysphoric children and adolescents: cortisol reactivity to psychosocial stress from preschool through middle adolescenceQ30496041
Are child-, adolescent-, and adult-onset depression one and the same disorder?Q30655315
Increased waking salivary cortisol and depression risk in preschoolers: the role of maternal history of melancholic depression and early child temperamentQ33583528
Comorbid depression and anxiety effects on pregnancy and neonatal outcomeQ33643050
Prospective prediction of major depressive disorder from cortisol awakening responses in adolescenceQ33872619
The corticosteroid receptor hypothesis of depressionQ34057906
The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory settingQ34060992
Life events, stress and depression: a review of recent findingsQ34126022
The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys.Q34209498
Psychoneuroendocrinological contributions to the etiology of depression, posttraumatic stress disorder, and stress-related bodily disorders: the role of the hypothalamus-pituitary-adrenal axisQ34309013
Biological studies in depressed children and adolescentsQ34315323
The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasisQ34350872
Life events and depression: The plot thickensQ34437966
Childhood adversity and adult psychiatric disorder in the US National Comorbidity SurveyQ34439540
A developmental psychopathology perspective on adolescenceQ34541340
The psychobiology of depression and resilience to stress: implications for prevention and treatmentQ34666840
Stress and depressionQ34666846
Early pubertal maturation and internalizing problems in adolescence: sex differences in the role of cortisol reactivity to interpersonal stressQ34703892
Pituitary-adrenal axis rhythm disturbances in psychiatric depression.Q48459415
The Excitatory Effects of the Amygdala on Hypothalamo-Pituitary-Adrenocortical Responses Are Mediated by Hypothalamic Norepinephrine, Serotonin, and CRF-41Q48496066
The corticotropin-releasing hormone challenge in depressed abused, depressed nonabused, and normal control childrenQ48610544
Unipolar depression in adolescents: clinical outcome in adulthoodQ48820908
24-hour cortisol measures in adolescents with major depression: a controlled studyQ48903659
Cortisol secretion in adolescents with major depressive disorderQ48940260
Depression in adolescents and young adults--polysomnographic and neuroendocrine aspectsQ48966022
Pituitary-Adrenal Function in Rats Chronically Exposed to ColdQ49013596
The 24-hour profile of adrenocorticotropin and cortisol in major depressive illnessQ49037226
Reduced cortisol latency in depressive illnessQ49112744
Corticotropin-releasing hormone challenge in prepubertal major depressionQ49116720
Correlation between serum and salivary cortisol levels in depressed and nondepressed children and adolescentsQ49201363
Resistance to suppression by dexamethasone of plasma 11-O.H.C.S. levels in severe depressive illnessQ49245400
Natural course of adolescent major depressive disorder: I. Continuity into young adulthoodQ50637471
Emergence of gender differences in depression during adolescence: national panel results from three countriesQ50691155
Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal studyQ50902337
Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentationQ51025935
Response to oCRH in depressed and nondepressed adolescents: does gender make a difference?Q51026346
Gender differences in emotional responses to interpersonal stress during adolescenceQ51050790
Family discord, parental depression, and psychopathology in offspring: ten-year follow-upQ51051166
The Yale Interpersonal Stressor (YIPS): affective, physiological, and behavioral responses to a novel interpersonal rejection paradigmQ51071931
Sex differences in adolescent depression: stress exposure and reactivity modelsQ51764353
Increased waking salivary cortisol levels in young people at familial risk of depressionQ51905234
Saliva cortisol and response to dexamethasone in children of depressed parentsQ51913111
Six-year predictors of problems in a national sample of children and youth: II. Signs of disturbanceQ52017235
Major depression in community adolescents: age at onset, episode duration, and time to recurrenceQ52025485
Biochemical profile of depressed adolescentsQ52073278
The dexamethasone suppression test in adolescent psychiatric patientsQ52092680
The dexamethasone suppression test in adolescent psychiatric inpatientsQ52095622
Six-year predictors of problems in a national sample of children and youth: I. Cross-informant syndromesQ52209596
Use of the dexamethasone suppression test with DSM-III criteria in psychiatrically hospitalized adolescentsQ52258403
Child's stress hormone levels correlate with mother's socioeconomic status and depressive state.Q54396895
Life Stressors as Risk Factors in DepressionQ56001450
Adrenocortical activity in at-risk and normally developing adolescents: Individual differences in salivary cortisol basal levels, diurnal variation, and responses to social challengesQ56863997
Developmental pathways in depression: Multiple meanings, antecedents, and endpointsQ59621576
Measurement of CortisolQ59702711
Disturbances in Morning Cortisol Secretion in Association with Maternal Postnatal Depression Predict Subsequent Depressive Symptomatology in AdolescentsQ61413030
Spontaneous afternoon plasma cortisol in depressionQ67299393
Correlation of serum and salivary cortisol levels in prepubertal school-aged childrenQ67980748
Dexamethasone suppression test in children with major depressive disorderQ68095991
The dexamethasone suppression test: an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in PsychiatryQ68192872
The dexamethasone suppression test in adolescent outpatients with major depressive disorderQ68220085
Neuroendocrine aspects of primary endogenous depression. I. Cortisol secretory dynamics in patients and matched controlsQ68982294
Depression and dexamethasone suppression testing in children and adolescentsQ69225443
Depression, anxiety and the dexamethasone suppression test in hospitalized prepubertal childrenQ69398473
Disrupted 24-hour Patterns of Cortisol Secretion in Psychotic DepressionQ69469970
Psychopathology and plasma cortisol responses to dexamethasone in prepubertal psychiatric inpatientsQ69774991
Adult sequelae of adolescent depressive symptomsQ70025807
Psychotic and depressed children: a new entityQ70051294
Self-report vs. biological markers in assessment of childhood depressionQ70067929
The dexamethasone suppression test in depressed, dysthymic, and nondepressed childrenQ70082242
Nocturnal cortisol, thyroid stimulating hormone, and growth hormone secretory profiles in depressed adolescentsQ70199452
The dexamethasone suppression test in prepubertal depressed childrenQ70279428
Pretreatment DST and Hypothalamic-Pituitary-Adrenocortical Function in Depressed Patients and Comparison GroupsQ70330394
Preliminary report on the dexamethasone suppression test in adolescentsQ70389395
The dexamethasone suppression test in depressed adolescentsQ70533930
The outcome of adolescent depression in the Ontario Child Health Study follow-upQ70550359
Cortisol secretion in relation to age in major depressionQ70841470
Effect of age and sex on cortisol secretion in depressives and normalsQ70973227
The dexamethasone suppression test in psychiatrically hospitalized adolescentsQ71072270
The dexamethasone suppression test in adolescent depressionQ71072274
Cortisol production rate. II. Normal infants, children, and adultsQ71168170
Abnormal dexamethasone suppression test results in depressed and nondepressed childrenQ71254143
The dexamethasone suppression test in hospitalized prepubertal depressed childrenQ71254313
Identification of depression in children and adolescents: the role of the dexamethasone suppression testQ71432315
A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utilityQ71465909
Case study: antimanic effectiveness of dextroamphetamine in a brain-injured adolescentQ72239348
Serial dexamethasone suppression tests (DST) in recently hospitalized childrenQ72775137
The impact of parental affective disorder on depression in offspring: a longitudinal follow-up in a nonreferred sampleQ72854495
Age and gender as determinants of stress exposure, generation, and reactions in youngsters: a transactional perspectiveQ77882229
Assessing salivary cortisol in studies of child developmentQ77893249
Polymorphisms of the glucocorticoid receptor gene and major depressionQ83036626
Psychoendocrine antecedents of persistent first-episode major depression in adolescents: a community-based longitudinal enquiryQ44464912
Neuroendocrine changes in affectively ill children and adolescentsQ44630616
Alterations in stress cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groupsQ44684787
Exposure to postnatal depression predicts elevated cortisol in adolescent offspringQ44762419
Prepartum, postpartum, and chronic depression effects on newbornsQ44893544
The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depressionQ44901515
Multiplicity of depressive episodes: phenomenological and neuroendocrine correlatesQ44944932
Acute HPA axis responses, heart rate, and mood changes to psychosocial stress (TSST) in humans at different times of day.Q44953284
Sex differences in the effects of pubertal development on responses to a corticotropin-releasing hormone challenge: the Pittsburgh psychobiologic studiesQ44976739
Twenty-four-hour cortisol secretion patterns in prepubertal children with anxiety or depressive disordersQ44991313
Characteristics of depressed preschoolers with and without anhedonia: evidence for a melancholic depressive subtype in young childrenQ45130099
Determinants of salivary cortisol levels in 10-12 year old children; a population-based study of individual differencesQ45274032
Maternal depression and anxiety across the postpartum year and infant social engagement, fear regulation, and stress reactivity.Q45922603
Plasma dexamethasone levels in children given the dexamethasone suppression testQ46243752
Age, gender, race, socioeconomic status, and birth cohort differences on the children's depression inventory: a meta-analysisQ46247207
Pulsatile rhythms of adrenocorticotropin (ACTH) and cortisol in women with endogenous depression: evidence for increased ACTH pulse frequencyQ46895060
Maternal and environmental factors influence the hypothalamic-pituitary-adrenal axis response to corticotropin-releasing hormone infusion in offspring of mothers with or without mood disordersQ46944766
Salivary Cortisol Levels throughout Childhood and Adolescence: Relation with Age, Pubertal Stage, and WeightQ47357036
Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axisQ47819047
Adrenocortical activity and emotion regulationQ48218565
Abnormal ACTH and cortisol responses to ovine corticotropin releasing factor in patients with primary affective disorderQ48416682
Psychoneuroendocrinology of depression. Hypothalamic-pituitary-gonadal axisQ48427598
The dexamethasone suppression test in prepubertal depressed childrenQ48430739
Cortisol secretion in endogenous depression. I. Basal plasma levelsQ48456214
Childhood and adolescent depression: a review of the past 10 years. Part I.Q34736609
Preclinical models: status of basic research in depressionQ34934319
Hypothalamic-pituitary-adrenal axis dysregulation in depressed children and adolescents: a meta-analysisQ34978595
The dexamethasone suppression test in children and adolescents: a review and a controlled studyQ35462018
Implication of the hypothalamic-pituitary-adrenal axis in the physiopathology of depressionQ35790395
Depression and cortisol responses to psychological stress: a meta-analysisQ36165619
The neurobiology of stress and developmentQ36563442
Preliminary data on the dexamethasone suppression test in children with major depressive disorderQ36633209
Effects of early and recent adverse experiences on adrenal response to psychosocial stress in depressed adolescentsQ36919606
Disorders of childhood and adolescence: gender and psychopathologyQ37120697
Electroencephalographic sleep and hypothalamic-pituitary-adrenal changes from episode to recovery in depressed adolescentsQ37166797
Incorporating hypothalamic-pituitary-adrenal axis measures into preventive interventions for adolescent depression: are we there yet?Q37208947
Stressor paradigms in developmental studies: what does and does not work to produce mean increases in salivary cortisolQ37217272
Peri-sleep-onset cortisol levels in children and adolescents with affective disordersQ37218186
Stress response and the adolescent transition: performance versus peer rejection stressorsQ37238100
Maternal depression and infant cortisol: influences of timing, comorbidity and treatmentQ37284647
Cortisol awakening response and psychosocial factors: a systematic review and meta-analysisQ37330758
Developmental changes in hypothalamus-pituitary-adrenal activity over the transition to adolescence: normative changes and associations with puberty.Q37600139
Hypothalamic-pituitary-adrenal axis in psychiatric disordersQ37723062
Comorbidity in the interpretation of dexamethasone suppression test results in children: a review and reportQ37944464
Children of depressed parents: an integrative reviewQ37945993
The DST in children and adolescents with major depressive disorderQ38613074
Cortisol secretion in prepubertal children with major depressive disorder. Episode and recoveryQ38686988
Low salivary cortisol levels and externalizing behavior problems in youthQ39268612
Temporal Changes in Plasma Adrenocorticotropin Concentration after Repeated Neurotropic Stress in Male and Female RatsQ40244626
The dexamethasone suppression test for melancholiaQ40342019
Self-reported depressive symptoms and stress levels in healthy young men: associations with the cortisol response to awakeningQ40608047
Depression scale scores in 8-17-year-olds: effects of age and genderQ40618815
Corticotropin releasing hormone in the pathophysiology of melancholic and atypical depression and in the mechanism of action of antidepressant drugsQ40967879
The psychosocial functioning and family environment of depressed adolescentsQ41087575
Generation of stress in the course of unipolar depressionQ41145131
Chronic stress, acute stress, and depressive symptomsQ41181965
The dexamethasone suppression test and the Children's Depression Inventory in psychiatric disorders in childrenQ41332689
Family-genetic studies of psychiatric disorders. Developing technologiesQ41346445
The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions.Q41445105
Validity of familial subtypes of primary unipolar depression. Clinical, demographic, and psychosocial correlates.Q41475105
The Clinical Course of Unipolar Major Depressive DisordersQ41641015
The development of depression in children and adolescents.Q41716217
Differences in plasma ACTH and cortisol between depressed patients and normal controlsQ42054104
Adrenocortical activity in at-risk and normally developing adolescents: individual differences in salivary cortisol basal levels, diurnal variation, and responses to social challengesQ43720729
Stress hormone levels of children of depressed mothersQ44005974
Sex differences in stress responses: social rejection versus achievement stressQ44123612
Maternal stress beginning in infancy may sensitize children to later stress exposure: effects on cortisol and behaviorQ44174102
Differentiating depressed adolescent 24 h cortisol secretion in light of their adult clinical outcomeQ44464143
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectchild developmentQ407784
teenagerQ1492760
mental depressionQ4340209
nervous systemQ9404
endocrine systemQ11078
physiological phenomenonQ66615932
P304page(s)135-160
P577publication date2011-06-01
P1433published inClinical Child and Family Psychology ReviewQ15761985
P1476titleIn search of HPA axis dysregulation in child and adolescent depression
In Search of HPA Axis Dysregulation in Child and Adolescent Depression
P478volume14

Reverse relations

cites work (P2860)
Q64230870A cross comparison between Ayurvedic etiology of Major Depressive Disorder and bidirectional effect of gut dysregulation
Q38764288A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children
Q37244949Acute psychological stress results in the rapid development of insulin resistance
Q91750965Adolescent Suicide as a Failure of Acute Stress-Response Systems
Q46434277Allostasis and the development of internalizing and externalizing problems: changing relations with physiological systems across adolescence
Q59487261An experimental test of the fetal programming hypothesis: Can we reduce child ontogenetic vulnerability to psychopathology by decreasing maternal depression?
Q47557842An exploratory analysis of the joint contribution of HPA axis activation and motivation to early adolescent depressive symptoms.
Q35894963Associations between DSM-IV diagnosis, psychiatric symptoms and morning cortisol levels in a community sample of adolescents
Q90248205Challenges to Identity Integration Indirectly Link Experiences of Heterosexist and Racist Discrimination to Lower Waking Salivary Cortisol in Sexually Diverse Latinx Emerging Adults
Q35153963Child anxiety symptoms related to longitudinal cortisol trajectories and acute stress responses: evidence of developmental stress sensitization
Q38806319Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults
Q44347024Co-development of early adolescent alcohol use and depressive feelings: The role of the mu-opioid receptor A118G polymorphism
Q47867457Cognitive control moderates parenting stress effects on children's diurnal cortisol
Q88692028Comparing Postnatal Development of Gonadal Hormones and Associated Social Behaviors in Rats, Mice, and Humans
Q35589031Concordance of mother-daughter diurnal cortisol production: Understanding the intergenerational transmission of risk for depression.
Q42015425Cortisol Response to Psychosocial Stress in Chinese Early Puberty Girls: Possible Role of Depressive Symptoms
Q41647694Cortisol response to family interaction as a predictor for adjustment
Q36720965Depression and Inflammatory Periodontal Disease Considerations-An Interdisciplinary Approach
Q46468206Dispositional and Environmental Predictors of the Development of Internalizing Problems in Childhood: Testing a Multilevel Model
Q45276279Does early-onset chronic or recurrent major depression impact outcomes with antidepressant medications? A CO-MED Trial Report
Q90434015Early socioeconomic adversity and cardiometabolic risk in young adults: mediating roles of risky health lifestyle and depressive symptoms
Q37287807Effects of prenatal and postnatal parent depressive symptoms on adopted child HPA regulation: independent and moderated influences
Q37627952Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms
Q36665297Eye tracking indices of attentional bias in children of depressed mothers: Polygenic influences help to clarify previous mixed findings.
Q47610199FKBP5 DNA methylation does not mediate the association between childhood maltreatment and depression symptom severity in the Detroit Neighborhood Health Study
Q33648462Future Directions in Vulnerability to Depression Among Youth: Integrating Risk Factors and Processes Across Multiple Levels of Analysis
Q36668325GABAergic control of depression-related brain states
Q47572853HPA axis multilocus genetic profile score moderates the impact of interpersonal stress on prospective increases in depressive symptoms for offspring of depressed mothers.
Q33597862HPA-axis stress reactivity in youth depression: evidence of impaired regulatory processes in depressed boys
Q38034063Hypothalamic-pituitary-adrenal axis dysfunction as a neurobiological correlate of emotion dysregulation in adolescent suicide
Q38366878Hypothalamic-pituitary-adrenal axis function during perinatal depression
Q49709780Impact of prenatal stress on mother-infant dyadic behavior during the still-face paradigm
Q37410351Infant adrenocortical reactivity and behavioral functioning: relation to early exposure to maternal intimate partner violence
Q48463110Infants at familial risk for depression show a distinct pattern of cortisol response to experimental challenge
Q89442993Integrating the Neurobiology of Minority Stress with an Intersectionality Framework for LGBTQ-Latinx Populations
Q57294596Interpersonal Stress Severity Longitudinally Predicts Adolescent Girls' Depressive Symptoms: the Moderating Role of Subjective and HPA Axis Stress Responses
Q90548155Interpersonal childhood adversity and stress generation in adolescence: Moderation by HPA axis multilocus genetic variation
Q46083776Major depression in young girls is related to altered cortisol awakening response
Q91669844Mediating Effect of Sleep Quality on the Relationship Between Problematic Mobile Phone Use and Depressive Symptoms in College Students
Q34772434Multi-Level Risk Factors for Suicidal Ideation Among at-Risk Adolescent Females: The Role of Hypothalamic-Pituitary-Adrenal Axis Responses to Stress
Q42648957Neuroendocrine predictors of emotional and behavioral adjustment in boys: Longitudinal follow-up of a community sample
Q48404959Persistent heightened cortisol awakening response and adolescent internalizing symptoms: a 3-year longitudinal community study.
Q46242754Poverty, early care, and stress reactivity in adolescence: Findings from a prospective, longitudinal study in South Africa.
Q35282383Predicting developmental changes in internalizing symptoms: examining the interplay between parenting and neuroendocrine stress reactivity.
Q36325115Predicting first onset of depression in young girls: Interaction of diurnal cortisol and negative life events
Q92366711Prenatal ethanol exposure enhances the susceptibility to depressive behavior of adult offspring rats fed a high‑fat diet by affecting BDNF‑associated pathway
Q34475426Raised by depressed parents: is it an environmental risk?
Q34160742Relational victimization, friendship, and adolescents' hypothalamic-pituitary-adrenal axis responses to an in vivo social stressor
Q43579005Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy
Q38169802Role of chronic stress and depression in periodontal diseases
Q38676622Rumination about Social Stress Mediates the Association between Peer Victimization and Depressive Symptoms during Middle Childhood
Q58698997Salivary biomarkers may measure stress responses in critically ill children
Q38308425Sleep in adolescent depression: physiological perspectives
Q36400123Stress Reactivity as a Pathway from Attentional Control Deficits in Everyday Life to Depressive Symptoms in Adolescent Girls.
Q39027715Stress and cortisol in disaster evacuees: an exploratory study on associations with social protective factors
Q90548242The codevelopment of internalizing symptoms, externalizing symptoms, and cognitive ability across childhood and adolescence
Q49596439The metamorphosis of adolescent hormonal stress reactivity: A focus on animal models
Q28570801The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells
Q45375015The role of the HPA-axis in understanding psychopathology: cause, consequence, mediator, or moderator?
Q37947985Timing is everything: evidence for a role of corticolimbic endocannabinoids in modulating hypothalamic–pituitary–adrenal axis activity across developmental periods
Q36337122Transcriptional signatures of steroid hormones in the striatal neurons and astrocytes
Q37648882Translational relevance of rodent models of hypothalamic-pituitary-adrenal function and stressors in adolescence
Q55402122Treatment of Major Depressive Disorder in Pediatric Populations.
Q35096791Youth offspring of mothers with posttraumatic stress disorder have altered stress reactivity in response to a laboratory stressor
Q55276164Zinc, Magnesium, Selenium and Depression: A Review of the Evidence, Potential Mechanisms and Implications.

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