Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation

scientific article

Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1999PNAS...96.1421L
P356DOI10.1073/PNAS.96.4.1421
P932PMC publication ID15478
P698PubMed publication ID9990039
P5875ResearchGate publication ID13299503

P2093author name stringX Zhu
D Baltimore
G Cheng
H H Lee
P W Dempsey
T P Parks
P2860cites workA novel RING finger protein interacts with the cytoplasmic domain of CD40Q24306382
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40Q24306620
Involvement of CRAF1, a relative of TRAF, in CD40 signalingQ24306746
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinomaQ24315735
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathwaysQ24317441
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signalingQ24634187
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2Q24642851
The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimersQ28260566
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptorQ28282051
TRAF6 is a signal transducer for interleukin-1Q28291934
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic regionQ28511583
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formationQ28586300
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
Production of high-titer helper-free retroviruses by transient transfectionQ29547802
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient miceQ29618716
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activationQ36564433
Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimersQ38299782
CD40 ligand and its role in X-linked hyper-IgM syndromeQ40385139
The role of CD40 in the regulation of humoral and cell-mediated immunityQ40393797
Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinasesQ41063531
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathwayQ41134913
CD40 signaling-mediated induction of Bcl-XL, Cdk4, and Cdk6. Implication of their cooperation in selective B cell growthQ41259834
Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosisQ41343773
Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B.Q41429303
Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiationQ41450875
Association between IL-6 and CD40 signaling. IL-6 induces phosphorylation of CD40 receptorsQ41724340
TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activationQ48064873
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.Q52522634
Mice deficient for the CD40 ligandQ72610555
Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cellsQ73302828
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survivalQ73925277
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P1104number of pages6
P304page(s)1421-1426
P577publication date1999-02-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSpecificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation
P478volume96

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cites work (P2860)
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Q73128939CD40-deficient dendritic cells producing interleukin-10, but not interleukin-12, induce T-cell hyporesponsiveness in vitro and prevent acute allograft rejection
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Q36211163Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.
Q41788230Expression of CD40 is a positive prognostic factor of diffuse large B-cell lymphoma treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
Q38462802Expression of the tumor necrosis factor receptor-associated factors (TRAFs) 1 and 2 is a characteristic feature of Hodgkin and Reed-Sternberg cells
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Q37291416TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.
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Q39613693TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells
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