Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy.

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Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy. is …
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scholarly articleQ13442814

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P356DOI10.1161/CIRCHEARTFAILURE.114.001218
P8608Fatcat IDrelease_w5jtyyjlqnanvgwih3577kte7q
P932PMC publication ID4303519
P698PubMed publication ID25278000

P50authorBrian L. StaufferQ48302717
P2093author name stringPenny Nelson
Carmen C Sucharov
Shelley D Miyamoto
Stephanie J Nakano
Matthew Movsesian
P2860cites workIncidence, causes, and outcomes of dilated cardiomyopathy in children.Q50791017
Ser16 prevails over Thr17 phospholamban phosphorylation in the beta-adrenergic regulation of cardiac relaxation.Q52979010
Failure of low doses of amrinone to produce sustained hemodynamic improvement in patients with severe chronic congestive heart failure.Q54465894
Assessment of long-term therapy with milrinone and the effects of milrinone withdrawalQ68858464
Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failureQ68982799
Systemic and coronary effects of intravenous milrinone and dobutamine in congestive heart failureQ70032077
Multicenter, double-blind study of intravenous milrinone for patients with acute heart failure in Japan. Japan Intravenous Milrinone InvestigatorsQ71513161
Immunodetection of phosphorylation sites gives new insights into the mechanisms underlying phospholamban phosphorylation in the intact heartQ71903446
Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human HeartsQ72933722
Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytesQ74558380
Clinical features and outcomes of childhood dilated cardiomyopathy: results from a national population-based studyQ79372337
Improved outcomes of pediatric dilated cardiomyopathy with utilization of heart transplantationQ80356169
Cardiac excitation-contraction couplingQ28216347
Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research GroupQ33157410
Evaluation of a new bipyridine inotropic agent--milrinone--in patients with severe congestive heart failureQ33482398
Pharmacokinetics and side effects of milrinone in infants and children after open heart surgeryQ33501588
Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human heartsQ34224951
Outpatient continuous parenteral inotropic therapy as bridge to transplantation in children with advanced heart failureQ36415090
Phosphodiesterase type 3A regulates basal myocardial contractility through interacting with sarcoplasmic reticulum calcium ATPase type 2a signaling complexes in mouse heartQ36630526
Home inotropic therapy in childrenQ36797958
β-Adrenergic receptor antagonism in mice: a model for pediatric heart disease.Q37235097
cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardiumQ37312871
Phosphodiesterase inhibition in heart failureQ37355108
Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy.Q37423781
The impact of changing medical therapy on transplantation-free survival in pediatric dilated cardiomyopathyQ37719083
Carvedilol for children and adolescents with heart failure: a randomized controlled trial.Q38395213
Basal and isoprenaline-stimulated cAMP content in failing versus nonfailing human cardiac preparationsQ41847220
Tachyphylaxis with amrinone therapy: association with sequestration and down-regulation of lymphocyte beta-adrenergic receptorsQ41955393
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB.Q42089521
Cardiotonic Activity of Milrinone, a New and Potent Cardiac Bipyridine, on the Normal and Failing Heart of Experimental AnimalsQ42243633
Milrinone: systemic and pulmonary hemodynamic effects in neonates after cardiac surgeryQ42276649
Milrinone and low cardiac output following cardiac surgery in infants: is there a direct myocardial effect?Q42669384
Prophylactic intravenous use of milrinone after cardiac operation in pediatrics (PRIMACORP) study. Prophylactic Intravenous Use of Milrinone After Cardiac Operation in PediatricsQ43843811
Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trialQ43930568
Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart diseaseQ44324618
Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF studyQ44371716
Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoterQ44445863
Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: results of a multicenter study in the United StatesQ44446042
Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardiumQ46711233
P4510describes a project that usesImageJQ1659584
P433issue1
P304page(s)57-63
P577publication date2014-10-02
P1433published inCirculation: Heart FailureQ2865806
P1476titleAge-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy
P478volume8

Reverse relations

cites work (P2860)
Q92365643A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium
Q57095323Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs
Q37742299Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment
Q48308293Clinical management of dilated cardiomyopathy: current knowledge and future perspectives
Q89375106Differential Response to Heart Failure Medications in Children
Q64081792Elamipretide Improves Mitochondrial Function in the Failing Human Heart
Q48302617Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes
Q50542706Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.
Q93241553From pediatrics to geriatrics: Mechanisms of heart failure across the life-course
Q39430716Genetics of paediatric cardiomyopathies
Q30235239Heart Failure in Pediatric Patients With Congenital Heart Disease
Q38678462Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy
Q48410009Molecular Changes in Children with Heart Failure Undergoing Left Ventricular Assist Device Therapy
Q37047994Myocardial Response to Milrinone in Single Right Ventricle Heart Disease
Q37240681Natural History of Dilated Cardiomyopathy in Children
Q40625826Oral Enoximone as an Alternative to Protracted Intravenous Medication in Severe Pediatric Myocardial Failure
Q41068198Pediatric dilated cardiomyopathy hearts display a unique gene expression profile

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