| scholarly article | Q13442814 |
| P50 | author | Giosuè Costa | Q45720105 |
| Stefano Alcaro | Q56811069 | ||
| Francesco Ortuso | Q42680440 | ||
| P2093 | author name string | Anna Artese | |
| Lucia Parrotta | |||
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| Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4 | Q81598760 | ||
| Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia | Q83230375 | ||
| Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening | Q84039722 | ||
| Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers. | Q44651221 | ||
| Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin. | Q44970279 | ||
| Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders. | Q46828661 | ||
| Analysis of telomerase activity and telomere function in cancer | Q47281888 | ||
| Evaluating virtual screening methods: good and bad metrics for the "early recognition" problem. | Q51922697 | ||
| Semianalytical treatment of solvation for molecular mechanics and dynamics | Q56866446 | ||
| Targeting telomeres and telomerase | Q57679134 | ||
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| Development of novel telomerase inhibitors based on a bisindole unit | Q31875879 | ||
| Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect | Q33302426 | ||
| A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes | Q33311334 | ||
| G-quadruplexes as targets for drug design | Q33876849 | ||
| Structural insights into G-quadruplexes: towards new anticancer drugs | Q33915919 | ||
| Analysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods | Q34122798 | ||
| How long is too long? Effects of loop size on G-quadruplex stability | Q34368029 | ||
| RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles | Q34401522 | ||
| Structure and variability of human chromosome ends | Q34419028 | ||
| Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids | Q34464213 | ||
| Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities. | Q34633824 | ||
| Telomere maintenance as a target for anticancer drug discovery | Q34743340 | ||
| Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors | Q35853278 | ||
| Chemical approaches to the discovery and development of cancer therapies | Q36085630 | ||
| Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects | Q36111294 | ||
| Targeting telomerase for cancer therapeutics | Q36484571 | ||
| Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics | Q36959489 | ||
| Evaluation of the performance of 3D virtual screening protocols: RMSD comparisons, enrichment assessments, and decoy selection--what can we learn from earlier mistakes? | Q37057393 | ||
| Telomerase and cancer therapeutics | Q37078833 | ||
| A hitchhiker's guide to G-quadruplex ligands | Q37080928 | ||
| Telomerase in the early detection of cancer | Q37202485 | ||
| NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA. | Q38333614 | ||
| Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells | Q38493959 | ||
| (3S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells. | Q39218882 | ||
| Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures. | Q39389811 | ||
| Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties. | Q39743117 | ||
| Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis | Q39802021 | ||
| Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation | Q40328181 | ||
| The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function. | Q40453766 | ||
| A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells | Q40503963 | ||
| Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase. | Q40575652 | ||
| A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity | Q40737219 | ||
| 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase | Q40941186 | ||
| HIV inhibitory natural products. 26. Quinoline alkaloids from Euodia roxburghiana | Q42554467 | ||
| Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures | Q42867856 | ||
| Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches | Q44124107 | ||
| The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers. | Q44503765 | ||
| Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways | Q44549002 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | virtual screening | Q4112105 |
| P304 | page(s) | 12051-12070 | |
| P577 | publication date | 2013-09-30 | |
| P1433 | published in | Molecules | Q151332 |
| P1476 | title | Identification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach | |
| P478 | volume | 18 |
| Q49103127 | A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences. |
| Q64068845 | Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases |
| Q38819605 | Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy |
| Q38302099 | In silico identification of novel ligands for G-quadruplex in the c-MYC promoter |
| Q47112508 | Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity |
| Q64256356 | Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures |
| Q38807466 | Quinazoline derivative from indigenous isolate, Nocardiopsis alba inhibits human telomerase enzyme |
| Q89597527 | Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations |
| Q55068987 | Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations. |
| Q38365328 | Targeting G-quadruplex structures with extrinsic fluorogenic dyes: promising fluorescence sensors |
| Q38238562 | Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? |
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