Hydroxyl radical in living systems and its separation methods

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Hydroxyl radical in living systems and its separation methods is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1570-0232(02)00620-7
P698PubMed publication ID12450675

P2093author name stringTung-Hu Tsai
Fu-Chou Cheng
Jen-Fon Jen
P2860cites workMeasurement of phagocytosis and cell-mediated cytotoxicity by chemiluminescenceQ23916330
Free radicals in the physiological control of cell functionQ27860480
In vivo evidence for accelerated generation of hydroxyl radicals in liver of Long-Evans Cinnamon (LEC) rats with acute hepatitisQ28176029
The Haber-Weiss cycle--70 years laterQ28201133
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluidsQ28360493
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxideQ29547245
Oxygen toxicity, oxygen radicals, transition metals and diseaseQ29615096
NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C.Q30463806
Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ionsQ30471061
Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysisQ32173941
What is the significance of increases in background levels of carcinogen-derived protein and DNA adducts? Some considerations for incremental risk assessmentQ33538121
Analysis of hepatic oxidative stress status by electron spin resonance spectroscopy and imagingQ33913132
The Haber-Weiss reaction and mechanisms of toxicityQ34017657
2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism.Q34175081
Oxidative stress and antioxidants in exerciseQ34263088
Signalling apoptosis: a radical approach.Q34307275
Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injuryQ34348724
Comparisons of ESR and HPLC methods for the detection of OH. radicals in ischemic/reperfused hearts. A relationship between the genesis of free radicals and reperfusion arrhythmiasQ72957806
Prazosin attenuates hydroxyl radical generation in the rat myocardiumQ73021480
Oxidation of acetaldehyde by peroxynitrite and hydrogen Peroxide/Iron(II). Production Of acetate, formate, and methyl radicalsQ73091988
Determination of hydroxyl radicals using salicylate as a trapping agent by gas chromatography-mass spectrometryQ73122983
The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis studyQ73178752
Identification of the oxidation products of the reaction between alpha-pinene and hydroxyl radicals by gas and high-performance liquid chromatography with mass spectrometric detectionQ73229497
Measurement of hydroxyl radical in rat blood vessel by microbore liquid chromatography and electrochemical detection: an on-line microdialysis studyQ73267363
Development of novel high-sensitivity chemiluminescence assay for luminol using thiourea derivativesQ73282835
Determination of salicylate hydroxylation products as an in vivo oxidative stress markerQ73308671
Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformationQ73308716
In vivo hydroxyl radical generation in the striatum following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in miceQ73416487
In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brainQ73453586
Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxyl radical damage of DNAQ73703055
Fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, resists hydroxyl radical generation in the rat myocardiumQ73797815
alpha-Phenyl-N-tert-butylnitrone attenuates excitotoxicity in rat striatum by preventing hydroxyl radical accumulationQ73848999
Methamphetamine enhances 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in the rat striatumQ74341512
Direct evidence for in vivo hydroxyl radical generation in blood of mice after acute chromium(VI) intake: electron spin resonance spin-trapping investigationQ74351200
Photodegradation and phototoxicity studies of furosemide. Involvement of singlet oxygen in the photoinduced hemolysis and lipid peroxidationQ74573825
Ferrous iron-induced luminol chemiluminescence: a method for hydroxyl radical studyQ77312867
Oxidative damage in the central nervous system: protection by melatoninQ77403298
LC/MS analysis of hydroxylation products of salicylate as an indicator of in vivo oxidative stressQ77416664
Identification of hydroxyhydroquinone in coffee as a generator of reactive oxygen species that break DNA single strandsQ77521177
Determination of free radical reaction products and metabolites of salicylic acid using capillary electrophoresis and micellar electrokinetic chromatographyQ77613792
In vivo trapping of hydroxyl free radicals in the striatum utilizing intracranial microdialysis perfusion of salicylate: effects of MPTP, MPDP+, and MPP+Q67505470
Colorimetric detection of the hydroxyl radical: Comparison of the hydroxyl-radical-generating ability of various iron complexesQ68481153
Use of salicylate as a probe for .OH formation in isolated ischemic rat heartsQ68483453
Intramolecular cyclization in irradiated nucleic acids: correlation between high-performance liquid chromatography and an immunochemical assay for 8,5'-cycloadenosine in irradiated poly(A)Q68973860
OH-induced free radicals in purine nucleoside monophosphates: e.s.r. and spin-trappingQ69366921
Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formationQ69380141
Reactions of the Hydroxyl Radical with PolynucleotidesQ69592853
Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNAQ69823166
Use of high-performance liquid chromatography to detect hydroxyl and superoxide radicals generated from mitomycin CQ70125597
Detection of oxidative stress in heart by estimating the dinitrophenylhydrazine derivative of malonaldehydeQ70791917
Mechanisms of protection by buthionine sulphoximine against gamma-ray-induced micronuclei in polychromatic erythrocytes of mouse bone marrowQ71120880
Suppression of hydroxyl radical formation and protection of nigral neurons by l-deprenyl (selegiline)Q71209002
Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidationsQ71316462
In vivo evidence of hydroxyl radical formation induced by elevation of extracellular glutamate after cerebral ischemia in the cortex of anesthetized ratsQ71363123
Relationship between the intracellular reactive oxygen species and the induction of oxidative DNA damage in human neutrophil-like cellsQ71408900
Detection of hydroxyl and carbon-centred radicals by EPR spectroscopy after ischaemia and reperfusion of the rat kidneyQ71549237
Mechanism of catechin chemiluminescence in the presence of active oxygenQ71621994
MAO inhibitors, clorgyline and lazabemide, prevent hydroxyl radical generation caused by brain ischemia/reperfusion in miceQ71764195
Evaluation of sodium 4-hydroxybenzoate as an hydroxyl radical trap using gas chromatography-mass spectrometry and high-performance liquid chromatography with electrochemical detectionQ71783918
Effect of in vivo iron supplementation on oxygen radical production by soybean rootsQ71938699
Detection of hydroxyl radicals by aromatic hydroxylationQ72024563
Na+, K+-ATPase, glutathione, and hydroxyl free radicals in cadmium chloride-induced testicular toxicity in miceQ72027827
Effect of dimethylthiourea on chromium (VI)-induced DNA single-strand breaks in Chinese hamster V-79 cellsQ72243864
Separation of dihydroxybenzoates, indicators of in-vivo hydroxyl free radical formation, in the presence of transmitter amines and some metabolites in rodent brain, using high-performance liquid chromatography with electrochemical detectionQ72253962
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemiaQ72552668
On the Ability of Nitrous Oxide to Convert Hydrated Electrons into Hydroxyl RadicalQ72611636
The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F)Q72748216
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reactionQ72855582
Catechol adrenergic agents enhance hydroxyl radical generation in xanthine oxidase systems containing ferritin: implications for ischemia/reperfusionQ72871206
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatmentQ34400646
Commentary the Measurement of Oxidative Damage to DNA by HPLC and GC/MS TechniquesQ34537704
Chemical determination of free radical-induced damage to DNAQ36409344
Direct evidence for in vivo hydroxyl-radical generation in experimental iron overload: an ESR spin-trapping investigationQ37597543
On the participation of higher oxidation states of iron and copper in Fenton reactionsQ38264357
What do we measure by a luminol-dependent chemiluminescence of phagocytes?Q38281979
Ascorbic acid, metal ions and the superoxide radicalQ40005681
Free-radical reactions induced by OH-radical attack on cytosine-related compounds: a study by a method combining ESR, spin trapping and HPLC.Q40514732
Salicylate trapping of .OH as a tool for studying post-ischemic oxidative injury in the isolated rat heartQ40578779
In vivo detection of radical adducts by electron spin resonanceQ40663439
Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytesQ40808758
Antioxidants in human health and diseaseQ41138320
Detection of activated O2 species in vitro and in rat lungs by chemiluminescenceQ41971778
Structural characterization of the products of hydroxyl-radical damage to leucine and their detection on proteinsQ42159744
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: application to activated human neutrophils and to the heme protein leghemoglobinQ42200785
Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metaboliteQ42274899
Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprussideQ42541677
Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heartQ43596605
6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatumQ43598293
Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reactionQ43621641
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatumQ43625070
Allopurinol suppresses para-nonylphenol and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatumQ43638383
Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generationQ43656849
Protective effect of tamoxifen on 1-methyl-4-phenylpyridine-induced hydroxyl radical generation in the rat striatumQ43678396
In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatumQ43720224
3,4-Dihydroxyphenylacetaldehyde and hydrogen peroxide generate a hydroxyl radical: possible role in Parkinson's disease pathogenesisQ43725921
Iron autoxidation and free radical generation: effects of buffers, ligands, and chelatorsQ43857567
Quantification of hydroxyl radical and its lack of relevance to myocardial injury during early reperfusion after graded ischemia in rat heartsQ44083121
Site-directed hydroxyl radical probing of the rRNA neighborhood of ribosomal protein S5.Q46088985
ESR evidence of attenuation of hydroxyl radical generation in rat cerebral ischemia-reperfusion model by oxypurinolQ48104978
Protective effect of imidaprilat, a new angiotensin-converting enzyme inhibitor against 1-methyl-4-phenylpyridinium ion-induced *OH generation in rat striatumQ48118361
Reserpine prevents hydroxyl radical formation by MPP+ in rat striatumQ48215384
Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation.Q48345402
Simultaneous measurement of monoamines, their metabolites and 2,3- and 2,5-dihydroxybenzoates by high-performance liquid chromatography with electrochemical detection. Application to rat brain dialysatesQ48345766
Effects of pergolide treatment on in vivo hydroxyl free radical formation during infusion of 6-hydroxydopamine in rat striatum.Q48352052
Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brainQ48370206
alpha-Phenyl-tert-butyl-nitrone (PBN) attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: an EPR studyQ48377200
Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+Q48416385
Glutamate induces hydroxyl radical formation in vivo via activation of nitric oxide synthase in Sprague-Dawley ratsQ48494796
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.Q48666244
Manganese-induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivoQ49044882
Mitochondrial generation of reactive oxygen species after brain ischemia in the rat.Q49157416
DNA strand-breaking activity and mutagenicity of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP), a Maillard reaction product of glucose and glycineQ50132189
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized ratQ51593272
Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution.Q53437840
Protective effect of histidine on potassium chloride depolarization enhances 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in the rat striatum.Q54450408
Hydroxylation of aromatic compounds as indices of hydroxyl radical production: a cautionary note revisited.Q54681869
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetaseQ61456117
Potassium chloride depolarization enhances MPP+-induced hydroxyl radical generation in the rat striatumQ64789872
Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detectionQ64854506
Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products.Q64989287
P433issue1-2
P304page(s)481-496
P577publication date2002-12-01
P1433published inJournal of Chromatography B Analytical Technologies in the Biomedical and Life SciencesQ2422407
P1476titleHydroxyl radical in living systems and its separation methods
P478volume781

Reverse relations

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