review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0014-2999(01)01175-X |
P698 | PubMed publication ID | 11525764 |
P50 | author | Russel J Reiter | Q89645924 |
P2093 | author name string | Cuzzocrea S | |
P2860 | cites work | Regulation of prostaglandin production in carrageenan-induced pleurisy by melatonin | Q78139312 |
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide | Q29547245 | ||
Superoxide radical and superoxide dismutases | Q29614204 | ||
Nitric oxide as a secretory product of mammalian cells | Q29620372 | ||
NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C. | Q30463806 | ||
Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase. | Q30463956 | ||
The oxidant/antioxidant network: role of melatonin | Q33543307 | ||
Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide | Q33657113 | ||
Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice | Q34262516 | ||
A review of the evidence supporting melatonin's role as an antioxidant | Q34312720 | ||
Melatonin: a peroxyl radical scavenger more effective than vitamin E. | Q34323905 | ||
Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis | Q34335212 | ||
Evaluation of the antioxidant activity of melatonin in vitro | Q34401507 | ||
Nitric oxide: a mediator in rat tubular hypoxia/reoxygenation injury | Q35067646 | ||
Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology | Q35933719 | ||
Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle | Q35960752 | ||
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart | Q35980011 | ||
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase | Q36011589 | ||
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects | Q36380660 | ||
Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry. | Q36817571 | ||
Prostaglandin endoperoxide synthase: regulation of enzyme expression | Q37335647 | ||
Melatonin: the chemical expression of darkness | Q37443826 | ||
Mechanisms of oxidant injury of cells | Q37781539 | ||
Free radicals and antioxidants in sepsis. | Q38568109 | ||
Down's syndrome: a pathology involving the lack of balance of reactive oxygen species | Q39485617 | ||
Mechanisms of lipid peroxidation | Q39843060 | ||
The Pineal and Its Hormones in the Control of Reproduction in Mammals* | Q40124874 | ||
Nitric oxide: role in neurotoxicity | Q40403994 | ||
New insights into the mode of action of anti-inflammatory drugs | Q40476391 | ||
The significance of the metabolism of the neurohormone melatonin: antioxidative protection and formation of bioactive substances | Q40796347 | ||
Cellular defenses against damage from reactive oxygen species | Q40808542 | ||
Free radicals as mediators of tissue injury and disease | Q40895574 | ||
Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals | Q40992973 | ||
Melatonin is a scavenger of peroxynitrite | Q41140748 | ||
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity | Q41488356 | ||
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. | Q41664189 | ||
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation | Q41827670 | ||
Drug modulation of antigen-induced paw oedema in guinea-pigs: effects of lipopolysaccharide, tumour necrosis factor and leucocyte depletion | Q41884742 | ||
Involvement of superoxide and xanthine oxidase in neutrophil-independent rat gastric damage induced by NO donors | Q41921333 | ||
Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients | Q42283943 | ||
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-induced pleurisy | Q42536751 | ||
Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes | Q42549059 | ||
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion | Q43173946 | ||
Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E-like antioxidant, in carrageenan-induced pleurisy | Q43188677 | ||
Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia. | Q43806157 | ||
Altered immune responses in mice lacking inducible nitric oxide synthase | Q44662136 | ||
Sustained inhibition of nitric oxide by NG-nitro-L-arginine improves myocardial function following ischemia/reperfusion in isolated perfused rat heart | Q45083961 | ||
Free radical scavenging effects of melatonin and serotonin: possible mechanism. | Q46189045 | ||
The importance of vitamin E in human nutrition | Q46208753 | ||
Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis | Q46575678 | ||
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures | Q48281625 | ||
Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury | Q48316742 | ||
N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB. | Q48485930 | ||
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia | Q48616927 | ||
Melatonin protects neurons from singlet oxygen-induced apoptosis. | Q50761811 | ||
Vitamin E protects human skeletal muscle from damage during surgical ischemia-reperfusion. | Q51546825 | ||
Endotoxin-induced oxidative stress in the rat small intestine: role of nitric oxide. | Q54592867 | ||
Melatonin-A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitroa | Q56212000 | ||
Scavenging of reactive oxygen species by melatonin | Q64132511 | ||
Peroxynitrite formation from macrophage-derived nitric oxide | Q67505344 | ||
Release of 15-hydroxy-5,8,11,13-eicosatetraenoic acid and cysteinyl-leukotrienes in carrageenin-induced inflammation: effect of non-steroidal anti-inflammatory drugs | Q68263104 | ||
Anti-Shock Effects of Human Superoxide Dismutase in Splanchnic Artery Occlusion (SAO) Shock | Q68441569 | ||
Phenyl-T-butyl-nitrone is active against traumatic shock in rats | Q68845719 | ||
Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate | Q69535584 | ||
H2O2-induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonin | Q70958064 | ||
Red-light-induced suppression of melatonin synthesis is mediated by N-methyl-D-aspartate receptor activation in retinally normal and retinally degenerate rats | Q70965497 | ||
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite | Q71089423 | ||
Melatonin as a therapeutic agent in experimental endotoxic shock | Q71551522 | ||
Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors | Q71572745 | ||
Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats | Q71598244 | ||
Characterization of the antioxidant effects of melatonin and related indoleamines in vitro | Q71605718 | ||
Melatonin reduces nitric oxide synthase activity in rat hypothalamus | Q71605727 | ||
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells | Q71611092 | ||
Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase | Q71647466 | ||
Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum | Q71661526 | ||
The role of free radicals in NMDA-dependent neurotoxicity | Q71679694 | ||
Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo | Q71691440 | ||
NMDA Receptor Activation Produces Concurrent Generation of Nitric Oxide and Reactive Oxygen Species: Implications for Cell Death | Q71832406 | ||
3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice | Q71894886 | ||
Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: Role of the hydroxamic groups | Q71958549 | ||
Poly(ADP‐Ribose) Synthetase Activation: An Early Indicator of Neurotoxic DNA Damage | Q71978528 | ||
Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells | Q72374996 | ||
Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion | Q72460791 | ||
Peroxynitrite-induced rat colitis--a new model of colonic inflammation | Q72638580 | ||
The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo | Q72828716 | ||
A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats | Q73066471 | ||
Augmentation of indices of oxidative damage in life-long melatonin-deficient rats | Q73215103 | ||
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity | Q73929017 | ||
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation | Q74075555 | ||
Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy | Q74425068 | ||
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation | Q74449667 | ||
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat | Q77051513 | ||
Alloxan acts as a prooxidant only under reducing conditions: influence of melatonin | Q77401000 | ||
Prevention of immune dysfunction and vitamin E loss by dehydroepiandrosterone and melatonin supplementation during murine retrovirus infection | Q77419217 | ||
A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation | Q77905838 | ||
P433 | issue | 1-2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pharmacology | Q128406 |
melatonin | Q180912 | ||
reperfusion injury | Q1413991 | ||
P304 | page(s) | 1-10 | |
P577 | publication date | 2001-08-01 | |
P1433 | published in | European Journal of Pharmacology | Q1376712 |
P1476 | title | Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury | |
P478 | volume | 426 |
Q44789810 | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors |
Q54367778 | A case-control study of melatonin receptor type 1A polymorphism and acute myocardial infarction in a Spanish population. |
Q51515734 | A rapid and sensitive method for hydroxyl radical detection on a microfluidic chip using an N-doped porous carbon nanofiber modified pencil graphite electrode. |
Q46692847 | Alleviation of maternal hyperthermia-induced early embryonic death by administration of melatonin to mice |
Q46946118 | Alpha-lipoic acid protects against renal ischaemia-reperfusion injury in rats |
Q44256911 | Amelioration of hepatic ischemia/reperfusion injury using indolepropionic acid |
Q36790186 | Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase |
Q34602426 | Beneficial effects of rutin and L-arginine coadministration in a rat model of liver ischemia-reperfusion injury. |
Q34533540 | Clinical Pharmacokinetics of Antioxidants and Their Impact on Systemic Oxidative Stress |
Q44026420 | Determination of melatonin in galenic preparations by LC and voltammetry |
Q35640162 | Do solar cycles influence giant cell arteritis and rheumatoid arthritis incidence? |
Q38560692 | Effects of aminoguanidine and melatonin on intestinal ischemia/reperfusion injury in rats: An assessor-blinded, controlled experimental study. |
Q43136654 | Effects of caffeic acid phenethyl ester and melatonin on distraction osteogenesis: an experimental study |
Q41904590 | Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis |
Q36182062 | Free radical scavengers in anaesthesiology and critical care |
Q46374561 | Glycyrrhizae Radix attenuates peroxynitrite-induced renal oxidative damage through inhibition of protein nitration |
Q42242564 | Green Tea Polyphenols for the Protection against Renal Damage Caused by Oxidative Stress |
Q46583445 | Green tea polyphenol extract attenuates ischemia/reperfusion injury of the gut. |
Q48097088 | Hibernation-based blood loss therapy increases survivability of lethal hemorrhagic shock in rats |
Q39241072 | Hydrogen-rich saline protects against ischemia/reperfusion injury in grafts after pancreas transplantations by reducing oxidative stress in rats |
Q35008854 | Hydroxyl radical in living systems and its separation methods |
Q35688862 | Lipopolysaccharide induces inducible nitric oxide synthase-dependent podocyte dysfunction via a hypoxia-inducible factor 1α and cell division control protein 42 and Ras-related C3 botulinum toxin substrate 1 pathway |
Q35817388 | Melatonin Attenuates Oxidative Damage Induced by Acrylamide In Vitro and In Vivo |
Q44558485 | Melatonin ameliorates oxidative organ damage induced by acute intra-abdominal compartment syndrome in rats. |
Q44392612 | Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion |
Q45955801 | Melatonin and its potential biological functions in the fruits of sweet cherry. |
Q47098709 | Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation |
Q50996967 | Melatonin counteracts the loss of agonist-evoked contraction of aortic rings induced by incubation. |
Q47608127 | Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. |
Q39377382 | Melatonin improves sleep in asthma: a randomized, double-blind, placebo-controlled study |
Q46970991 | Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection |
Q44530232 | Melatonin protects against lipid peroxidation and membrane rigidity in erythrocytes from patients undergoing cardiopulmonary bypass surgery |
Q44604272 | Melatonin protects against myocardial doxorubicin toxicity in rats: role of physiological concentrations |
Q46742288 | Melatonin protects from the long-term consequences of a neonatal hypoxic-ischemic brain injury in rats |
Q44275611 | Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis |
Q24790971 | Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kappaB |
Q37203835 | Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats |
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Q44187161 | Myocardial ischemia-reperfusion in rats: reduction of infarct size by either supplemental physiological or pharmacological doses of melatonin |
Q38188467 | Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement |
Q44744697 | Octreotide improves reperfusion-induced oxidative injury in acute abdominal hypertension in rats |
Q44530217 | Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-beta peptide in rat brain: a comparative, in vivo study versus vitamin C and E. |
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Q46679535 | Protective effect of melatonin against ischemia/reperfusion-induced oxidative remote organ injury in the rat. |
Q52578514 | Protective effect of melatonin in acetic acid induced colitis in rats. |
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Q87320677 | Protective effect of melatonin on infrarenal aortic occlusion: this effect is related to anti-inflammatory effect and antioxidant effect |
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