A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation

scientific article published on 01 December 1998

A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1006/BBRC.1998.9826
P698PubMed publication ID9918777

P2093author name stringS T Weintraub
A M Shepherd
D X Tan
R J Reiter
Vijayalaxmi
L C Manchester
L J Hardies
B F Plummer
P433issue3
P921main subjectbiomarkerQ864574
P304page(s)614-620
P577publication date1998-12-01
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleA novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation
P478volume253

Reverse relations

cites work (P2860)
Q733997615-methoxytryptophol preserves hepatic microsomal membrane fluidity during oxidative stress
Q442775566-Hydroxymelatonin converts Fe (III) to Fe (II) and reduces iron-induced lipid peroxidation
Q36513111A metabolomic perspective of melatonin metabolism in the mouse
Q89659975ABTS/PP Decolorization Assay of Antioxidant Capacity Reaction Pathways
Q38221495Action of melatonin on squamous cell carcinoma and other tumors of the oral cavity (Review).
Q83611977Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes
Q22306050Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance
Q73215103Augmentation of indices of oxidative damage in life-long melatonin-deficient rats
Q39160691Chromium(III)-induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E.
Q32145214Comparison of the protective effect of melatonin with other antioxidants in the hamster kidney model of estradiol-induced DNA damage.
Q44187167Decreased nocturnal melatonin levels during acute myocardial infarction
Q58725798Dietary Melatonin Supplementation Could Be a Promising Preventing/Therapeutic Approach for a Variety of Liver Diseases
Q42521327Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels, and their responses to an inflammatory stimulus
Q42127267Effect of chronic L-dopa or melatonin treatments after dopamine deafferentation in rats: dyskinesia, motor performance, and cytological analysis.
Q43264206Effect of melatonin in the antioxidant defense system in the locomotor muscles of the estuarine crab Neohelice granulata (Decapoda, Brachyura).
Q46576799Effects of hypoxia and reoxygenation on the antioxidant defense system of the locomotor muscle of the crab Neohelice granulata (Decapoda, Varunidae).
Q22305604Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions
Q44251425Further insights into the reaction of melatonin with hydroxyl radical
Q44130673Hepatic mitochondrial dysfunction in senescence-accelerated mice: correction by long-term, orally administered physiological levels of melatonin
Q37823548Hepatoprotective actions of melatonin: possible mediation by melatonin receptors
Q34506503High physiological levels of melatonin in the bile of mammals
Q59489066Identification of highly elevated levels of melatonin in bone marrow: its origin and significance
Q37204822Identify Melatonin as a Novel Therapeutic Reagent in the Treatment of 1-Bromopropane(1-BP) Intoxication
Q73310231Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney
Q44380563Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.
Q37158649Melatonin ameliorates experimental hepatic fibrosis induced by carbon tetrachloride in rats
Q39443537Melatonin ameliorates oxidative stress and induces cellular proliferation of lymphoid tissues of a tropical rodent, Funambulus pennanti, during reproductively active phase
Q33838766Melatonin and Fertoprotective Adjuvants: Prevention against Premature Ovarian Failure during Chemotherapy
Q36282830Melatonin and Parkinson's disease
Q34416921Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value
Q59489061Melatonin and its derivatives cyclic 3-hydroxymelatonin, N1-acetyl-N2-formyl-5-methoxykynuramine and 6-methoxymelatonin reduce oxidative DNA damage induced by Fenton reagents
Q44446639Melatonin and pinoline prevent aluminium-induced lipid peroxidation in rat synaptosomes
Q24648452Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage
Q38022179Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes
Q44120560Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro
Q34359618Melatonin combats molecular terrorism at the mitochondrial level
Q73308716Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation
Q43930997Melatonin improves deferoxamine antioxidant activity in protecting against lipid peroxidation caused by hydrogen peroxide in rat brain homogenates
Q26765826Melatonin in Plants - Diversity of Levels and Multiplicity of Functions
Q36040915Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.
Q35001051Melatonin in mitochondrial dysfunction and related disorders
Q30476606Melatonin metabolism in the central nervous system
Q43593648Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+.
Q44604274Melatonin protects against pro‐oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitrite
Q35916483Melatonin protects lung mitochondria from aging
Q44034625Melatonin reduces memory changes and neural oxidative damage in mice treated with D-galactose
Q43992290Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse
Q59489064Melatonin reduces oxidative neurotoxicity due to quinolinic acid:
Q73222977Melatonin reduces phenylhydrazine-induced oxidative damage to cellular membranes: evidence for the involvement of iron
Q73103741Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid
Q44558496Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication
Q53101536Melatonin transport into mitochondria.
Q44066530Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs
Q24815611Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug
Q62071833Melatonin: A Versatile Protector against Oxidative DNA Damage
Q37755679Melatonin: a multitasking molecule
Q35145596Melatonin: clinical relevance
Q44604277Melatonin: structural characterization of its non-enzymatic mono-oxygenate metabolite
Q37898562Mitochondrial DNA and inflammatory diseases.
Q22241837Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development
Q37007219Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases.
Q22305781Neurotoxins: free radical mechanisms and melatonin protection
Q44530239Oxidation of melatonin by singlet molecular oxygen (O2(1deltag)) produces N1-acetyl-N2-formyl-5-methoxykynurenine
Q34348724Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury
Q44288274Possible mechanism of action in melatonin attenuation of haloperidol-induced orofacial dyskinesia
Q44340064Preventive effect of melatonin on the progression of alpha-naphthylisothiocyanate-induced acute liver injury in rats
Q73109141Protective effect of beta-carbolines and other antioxidants on lipid peroxidation due to hydrogen peroxide in rat brain homogenates
Q44462680Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver
Q73133376Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation
Q28387506Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure
Q34667176Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin
Q28081936Regulatory roles of serotonin and melatonin in abiotic stress tolerance in plants
Q44086407Role of exogenous melatonin in reducing the nephrotoxic effect of daunorubicin and doxorubicin in the rat.
Q59489068Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative stress
Q46257143Taxon- and Site-Specific Melatonin Catabolism
Q35027014The chemistry of melatonin's interaction with reactive species
Q35276597Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection
Q30320762Transformation of barbituric acid into alloxan by hydroxyl radicals: interaction with melatonin and with other hydroxyl radical scavengers.
Q34567568Urinary metabolites and antioxidant products of exogenous melatonin in the mouse
Q43574368Weak vasoconstrictor activity of melatonin in human umbilical artery: relation to nitric oxide-scavenging action

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