The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function

scientific article

The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/22.15.3181
P932PMC publication ID310294
P698PubMed publication ID8065934
P5875ResearchGate publication ID15133182

P2093author name stringMiesfeld RL
Chamberlain NL
Driver ED
P2860cites workBiological Actions of AndrogensQ22306226
Use of T7 RNA polymerase to direct expression of cloned genesQ27860692
Cloning of Human Androgen Receptor Complementary DNA and Localization to the X ChromosomeQ28118052
Cloning of a transcriptionally active human TATA binding factorQ28118101
Primary structure and expression of a functional human glucocorticoid receptor cDNAQ28282278
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptorsQ29615768
Gene regulation by steroid hormonesQ29618291
Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptorsQ33651363
Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogasterQ33879731
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophyQ34023072
Cloning, structure and expression of a cDNA encoding the human androgen receptorQ34049755
Human genetic diseases due to codon reiteration: relationship to an evolutionary mechanismQ72233686
Dominant negative regulation of trans-activation by the rat androgen receptor: roles of the N-terminal domain and heterodimer formationQ72258740
Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophyQ72635320
Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive traitQ34051849
Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteinsQ34163692
Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophyQ34231877
A family with adult spinal and bulbar muscular atrophy, X-linked inheritance and associated testicular failureQ34266153
Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.Q34353488
opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogasterQ34563922
Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groupsQ34614818
Domains of the Human Androgen Receptor Involved in Steroid Binding, Transcriptional Activation, and Subcellular LocalizationQ34671706
Transcriptional activation and nuclear targeting signals of the human androgen receptor.Q35009652
Dynamic mutations: a new class of mutations causing human diseaseQ35782791
A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicular-feminized mouseQ35804705
The rat androgen receptor: primary structure, autoregulation of its messenger ribonucleic acid, and immunocytochemical localization of the receptor proteinQ36440122
Androgen resistance caused by mutations in the androgen receptor gene.Q36831018
X-linked recessive bulbospinal neuronopathy: a report of ten casesQ37027303
Activators and targetsQ37856107
A novel regulatory element associated with age-dependent expression of the rat androgen receptor geneQ38313441
Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptorsQ38340343
Transcriptional repression of eukaryotic promotersQ38365817
Cellular analyses of hormone influence on motoneuronal development and functionQ39734145
Heterogeneity in the polyglutamine tract of the glucocorticoid receptor from different rat strainsQ40406692
Transcriptional transactivation functions localized to the glucocorticoid receptor N terminus are necessary for steroid induction of lymphocyte apoptosisQ40653917
Transcriptional activation modulated by homopolymeric glutamine and proline stretchesQ41488003
Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positionsQ41543354
Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response elementQ41572923
Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin geneQ41580505
Characterization of a panel of rat ventral prostate epithelial cell lines immortalized in the presence or absence of androgensQ41597156
Multiple components of a complex androgen-dependent enhancerQ41658230
Timing and duration of dihydrotestosterone treatment affect the development of motoneuron number and morphology in a sexually dimorphic rat spinal nucleusQ41839154
The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteinsQ42080838
Functional domains of the human glucocorticoid receptorQ43734761
Functional characterizations of the androgen receptor confirm that the molecular basis of androgen action is transcriptional regulationQ43884151
Structure and size distribution of the androgen receptor mRNA in wild-type and Tfm/Y mutant miceQ44508084
Identification of a thyroid hormone receptor that is pituitary-specificQ44748833
In vitro transcription enhancement by purified derivatives of the glucocorticoid receptor.Q46016097
Aberrant androgen action and increased size of tandem CAG repeat in androgen receptor gene in X-linked recessive bulbospinal neuronopathyQ47379781
Severity of X-linked recessive bulbospinal neuronopathy correlates with size of the tandem CAG repeat in androgen receptor geneQ47404452
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID).Q51166921
Crossing the threshold.Q52230019
[72] Identification of regulatory elements of cloned genes with functional assaysQ62397562
Strong correlation between the number of CAG repeats in androgen receptor genes and the clinical onset of features of spinal and bulbar muscular atrophyQ67600935
Androgen receptor abnormality in X-linked spinal and bulbar muscular atrophyQ68028965
Glucocorticoid receptor mutants that define a small region sufficient for enhancer activationQ68975768
Administration of testosterone attenuates neuronal loss following axotomy in the brain-stem motor nuclei of female ratsQ69386582
Testosterone-induced acceleration of recovery from facial paralysis following crush axotomy of the facial nerve in male hamstersQ69650080
Genome projects are growing like weedsQ69659441
Kennedy's disease: a clinicopathologic correlation with mutations in the androgen receptor geneQ70651007
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)3181-3186
P577publication date1994-08-01
P1433published inNucleic Acids ResearchQ135122
P1476titleThe length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
P478volume22

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cites work (P2860)
Q377123862D:4D ratio in children at familial high-risk for eating disorders: The role of prenatal testosterone exposure
Q28200053A candidate prostate cancer susceptibility gene at chromosome 17p
Q47621371A case-based evaluation of SRD5A1, SRD5A2, AR, and ADRA1A as candidate genes for severity of BPH.
Q35605845A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).
Q34113217A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
Q44415291A multigene test for the risk of sporadic breast carcinoma
Q34707254A novel method for the analysis of the androgen receptor
Q34698933A phase II evaluation of goserelin and bicalutamide in patients with ovarian cancer in second or higher complete clinical disease remission.
Q34507367A potential novel spontaneous preterm birth gene, AR, identified by linkage and association analysis of X chromosomal markers
Q37270889A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis
Q34565351A review of genetic polymorphisms and prostate cancer risk
Q37387072A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation
Q42792854A safety study of administration of parenteral testosterone undecanoate to elderly men over minimally 24 months
Q33241980AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines
Q30445140Abnormalities of germ cell maturation and sertoli cell cytoskeleton in androgen receptor 113 CAG knock-in mice reveal toxic effects of the mutant protein
Q56679619Advances in male contraception
Q44399756Aerobic exercise and bone mineral density in middle-aged finnish men: a controlled randomized trial with reference to androgen receptor, aromatase, and estrogen receptor α gene polymorphisms
Q37282979Aggression and polymorphisms in AR, DAT1, DRD2, and COMT genes in Datoga pastoralists of Tanzania
Q85241142Aggression, Digit Ratio and Variation in Androgen Receptor and Monoamine Oxidase A Genes in Men
Q43939196Aggression, digit ratio, and variation in the androgen receptor, serotonin transporter, and dopamine D4 receptor genes in African foragers: the Hadza.
Q37331263Altered RNA splicing contributes to skeletal muscle pathology in Kennedy disease knock-in mice
Q53411360Altered expression of androgen-receptor isoforms in human colon-cancer tissues.
Q51904643An increased CAG repeat length in the androgen receptor gene in azoospermic ICSI candidates.
Q47999661Analysis of G/A polymorphism in the androgen response element I of the PSA gene and its interactions with the androgen receptor polymorphisms
Q37422378Androgen Receptor Gene CAG Repeat Polymorphism Regulates the Metabolic Effects of Testosterone Replacement Therapy in Male Postsurgical Hypogonadotropic Hypogonadism
Q35751403Androgen Receptor Gene Polymorphism, Aggression, and Reproduction in Tanzanian Foragers and Pastoralists
Q43596593Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors.
Q33869547Androgen insensitivity.
Q34043875Androgen receptor (AR) gene CAG trinucleotide repeat length associated with body composition measures in non-syndromic obese, non-obese and Prader-Willi syndrome individuals
Q27013914Androgen receptor (AR) pathophysiological roles in androgen-related diseases in skin, bone/muscle, metabolic syndrome and neuron/immune systems: lessons learned from mice lacking AR in specific cells
Q47233293Androgen receptor CAG and GGC polymorphisms in Mediterraneans: repeat dynamics and population relationships
Q33723560Androgen receptor CAG repeat length and risk of biliary tract cancer and stones
Q78439258Androgen receptor CAG repeat length in Jewish Israeli women who are BRCA1/2 mutation carriers: association with breast/ovarian cancer phenotype
Q37523512Androgen receptor CAG repeat length is not associated with the risk of incident symptomatic benign prostatic hyperplasia: results from the Prostate Cancer Prevention Trial
Q28475309Androgen receptor CAG repeat polymorphism and epigenetic influence among the south Indian women with Polycystic Ovary Syndrome
Q34287725Androgen receptor CAG repeat polymorphism and risk of TMPRSS2:ERG-positive prostate cancer
Q79222833Androgen receptor CAG repeat polymorphism in prostate cancer from a Brazilian population
Q45065643Androgen receptor CAG repeat polymorphism is associated with fat-free mass in men.
Q35209313Androgen receptor CAG repeat size is associated with stress fracture risk: a pilot study
Q35014537Androgen receptor CAG repeats length polymorphism and the risk of polycystic ovarian syndrome (PCOS)
Q44677957Androgen receptor GGC polymorphism and testosterone levels associated with high risk of prostate cancer and benign prostatic hyperplasia
Q34879760Androgen receptor and monoamine oxidase polymorphism in wild bonobos
Q39997315Androgen receptor cytosine-adenine-guanine repeat polymorphisms modulate EGFR signaling in epithelial ovarian carcinomas
Q44659948Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer
Q34490999Androgen receptor gene CAG repeat length varies in a race-specific fashion in men without prostate cancer
Q44118558Androgen receptor gene CAG(n) trinucleotide repeats polymorphism in Chinese women with polycystic ovary syndrome
Q34993797Androgen receptor gene and male genital anomaly.
Q33576938Androgen receptor gene and sex-specific Alzheimer's disease
Q38062708Androgen receptor gene polymorphism and polycystic ovary syndrome.
Q37074233Androgen receptor gene polymorphism and sex hormones in elderly men: the Tromsø study
Q28647118Androgen receptor gene polymorphism in zebra species
Q40244118Androgen receptor gene polymorphism influence fat accumulation: A longitudinal study from adolescence to adult age.
Q35202414Androgen receptor gene polymorphisms are associated with aggression in Japanese Akita Inu
Q54462904Androgen receptor gene sequence and basal cortisol concentrations predict men's hormonal responses to potential mates.
Q40931377Androgen receptor phosphorylation
Q35127580Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1.
Q47227720Androgen receptor polyglutamine repeat length (AR-CAGn) modulates the effect of testosterone on androgen-associated somatic traits in Filipino young adult men.
Q35553247Androgen receptor polyglutamine repeat length affects receptor activity and C2C12 cell development
Q34769670Androgen receptor polyglutamine tract length in Egyptian male breast cancer patients
Q47793235Androgen receptor polymorphisms (CAG repeat lengths) in androgenetic alopecia, hirsutism, and acne
Q53267259Androgen receptor polymorphisms and endometrial cancer risk.
Q34068244Androgen receptor status predicts response to chemotherapy, not risk of breast cancer in Indian women
Q36503027Androgen receptor variants and prostate cancer in humanized AR mice.
Q38780007Androgen receptor-related diseases: what do we know?
Q42261015Androgen receptor-target genes in african american prostate cancer disparities
Q37256846Androgen receptor: role and novel therapeutic prospects in prostate cancer
Q34247095Androgen receptors and their biology
Q24296691Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation
Q55357541Androgen-Induced Immunosuppression.
Q24673304Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model
Q41205966Androgen-receptor gene structure and function in prostate cancer
Q35659922Androgens and adipose tissue in males: a complex and reciprocal interplay
Q37084126Androgens and male aging: Current evidence of safety and efficacy
Q30251924Anogenital distance as a marker of androgen exposure in humans
Q21147080Anxiety, sex-linked behaviors, and digit ratios (2D:4D)
Q34446570Are there CAG repeat expansion-related disorders outside the central nervous system?
Q57632738Aspectos Moleculares da Determinação e Diferenciação Sexual
Q42403123Assessment of Correlation between Androgen Receptor CAG Repeat Length and Infertility in Infertile Men Living in Khuzestan, Iran
Q37553969Association Study of Polymorphisms of Epidermal Growth Factor and Epidermal Growth Factor Receptor With Benign Prostatic Hyperplasia in a Korean Population.
Q47782821Association between G1733A (rs6152) polymorphism in androgen receptor gene and recurrent spontaneous abortions in Mexican population
Q45253544Association between androgen receptor gene CAG repeat polymorphism and plasma testosterone levels in postmenopausal women.
Q34608698Association between genetic polymorphisms in androgen receptor gene and the risk of preeclampsia in Korean women
Q36661085Association of androgen receptor CAG repeat polymorphism and polycystic ovary syndrome
Q35889612Association of androgen receptor GGN repeat length polymorphism and male infertility in Khuzestan, Iran
Q56513773Association of androgen receptor exon 1 CAG repeat length with risk of hepatocellular carcinoma: a case-control study
Q48168790Association of androgen receptor gene CAG and GGN repeat polymorphism with cryptorchidism: A meta-analysis
Q54693792Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women.
Q51757080Association of tri-nucleotide (CAG and GGC) repeat polymorphism of androgen receptor gene in Taiwanese women with refractory or remission rheumatoid arthritis.
Q41717834BDNF regulation of androgen receptor expression in axotomized SNB motoneurons of adult male rats
Q34574410Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia.
Q34457175Behavioral and genetic correlates of the neural response to infant crying among human fathers
Q37826806Bone density and risk of osteoporosis in Klinefelter syndrome
Q42140110Bulbocavernosus muscle area measurement: a novel method to assess androgenic activity
Q37181453CAG Repeat Number in the Androgen Receptor Gene and Prostate Cancer.
Q79568360CAG and CTG repeat polymorphism in exons of human genes shows distinct features at the expandable loci
Q92004313CAG polymorphism in the androgen receptor gene in women may be associated with nodulocystic acne
Q39272843CAG repeat length in androgen receptor gene and male infertility in Egyptian patients.
Q36619671CAG repeat length in the androgen receptor gene is related to age at diagnosis of prostate cancer and response to endocrine therapy, but not to prostate cancer risk
Q53201491CTG Triplet Repeat in Mouse Growth Inhibitory Factor/Metallothionein III Gene Promoter Represses the Transcriptional Activity of the Heterologous Promoters
Q92723351Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213
Q36218806Cell-based assays for screening androgen receptor ligands
Q28509836Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
Q82029161Chapter 8 Spinobulbar muscular atrophy (Kennedy's disease)
Q58577846Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1
Q40717386Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3.
Q61446675Child sexual offenders show prenatal and epigenetic alterations of the androgen system
Q39468132Clinical characteristics and biopsy specimen features in African-American and white men without prostate cancer
Q34769679Clinical profile, BRCA2 expression, and the androgen receptor CAG repeat region in Egyptian and Moroccan male breast cancer patients
Q42680540Cloning and expression analysis of androgen receptor gene in chicken embryogenesis
Q57744393Combined profile of the tandem repeats CAG, TA and CA of the androgen and estrogen receptor genes in breast cancer
Q36430744Common genetic polymorphisms and prognosis of sporadic cancers: prostate cancer as a model
Q34047435Comparative studies of prostate cancer in Japan versus the United States. A review
Q90678415Comparison of NGS panel and Sanger sequencing for genotyping CAG repeats in the AR gene
Q46935757Comparison of androgen receptor CAG and GGN repeat length polymorphism in humans and apes
Q51761006Comparison of the polymorphisms of androgen receptor gene and estrogen alpha and beta gene between adolescent females with first-onset major depressive disorder and controls.
Q38572877Contemporary perspective and management of testosterone deficiency: Modifiable factors and variable management
Q33802277Contribution of allelic variability in prostate specific antigen (PSA) & androgen receptor (AR) genes to serum PSA levels in men with prostate cancer
Q35809733Cortisol and testosterone increase financial risk taking and may destabilize markets
Q35863711Cryptorchidism: diagnosis, treatment, and long-term prognosis
Q60920049Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia
Q41860888Cytoplasmic localization and the choice of ligand determine aggregate formation by androgen receptor with amplified polyglutamine stretch
Q93081557Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression
Q41157407Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domain
Q73082853Determination of CAG repeat length in the androgen-receptor gene using frozen serum
Q40611725Development of models to predict anabolic response to testosterone administration in healthy young men.
Q37883014Differing levels of testosterone and the prostate: a physiological interplay
Q30405382Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
Q37210875Diverse roles of androgen receptor (AR) domains in AR-mediated signaling
Q36773464Drug insight: role of the androgen receptor in the development and progression of prostate cancer
Q55478794Effects of androgen receptor polyglutamine tract expansion on proliferation of NG108-15 cells.
Q90116631Endogenous testosterone correlates with parochial altruism in relation to costly punishment in different social settings
Q35990415Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein
Q44005507Epidemiology of prostatic cancer in East Asia
Q22251432Etiologies underlying sex differences in Autism Spectrum Disorders
Q38291027Evidence for association of sex hormone-binding globulin and androgen receptor genes with semen quality.
Q42868254Expression of humoral autoimmunity is related to androgen receptor CAG repeat length in men with systemic lupus erythematosus
Q47825253Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Q38662854Functional significance of men's testosterone reactivity to social stimuli
Q34565746GGN repeat length and GGN/CAG haplotype variations in the androgen receptor gene and prostate cancer risk in south Indian men.
Q29040033Gain in Transcriptional Activity by Primate-specific Coevolution of Melanoma Antigen-A11 and Its Interaction Site in Androgen Receptor
Q37084474Gene-environment interaction and male reproductive function
Q35989056Gene-environment interactions: a review of effects on reproduction and development
Q37206980Genetic Association Between Androgen Receptor Gene CAG Repeat Length Polymorphism and Male Infertility: A Meta-Analysis
Q53693885Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology.
Q58797229Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease
Q53438178Genetic alterations of androgen receptor gene in Japanese human prostate cancer.
Q46922203Genetic analysis of a family with 46,XY "female" associated with infertility
Q38368023Genetic and environmental factors in the aetiology of hypospadias.
Q37139054Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men.
Q38736949Genetic architecture of acne vulgaris.
Q37945125Genetic determinants of aggression and impulsivity in humans
Q35064240Genetic diseases in adults
Q57565186Genetic impact on prostate anatomical variability during ageing: role of CYP17, SRD5A2 and androgen receptor genes polymorphisms
Q35592722Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men
Q35597290Genetic polymorphisms and prostate cancer risk
Q37454788Genetic variation in the androgen receptor gene and endometrial cancer risk
Q34557770Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia
Q38460006Genetics of androgen metabolism in women with infertility and hypoandrogenism
Q82245844Genetics of polycystic ovary syndrome
Q52585939Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero.
Q36845131Genomic biomarkers, androgen pathway and prostate cancer.
Q34388792Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation
Q40123008Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells
Q35062376Handedness and the X chromosome: the role of androgen receptor CAG-repeat length
Q45944320Height, obesity, and the risk of TMPRSS2:ERG-defined prostate cancer.
Q56928447Hereditary breast cancer
Q35452137Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types
Q35438009High frequency of skewed X inactivation in young breast cancer patients
Q38256197Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review.
Q37026024Hormonal and genetic control of testicular descent
Q35102851Hormonal prevention of prostate cancer
Q37721629Hormonal profile and androgen receptor study in prepubertal girls with hypertrichosis
Q34732880Hormones and prostate cancer: current perspectives and future directions
Q35687198Hormones and prostate carcinogenesis: Androgens and estrogens
Q41084579How is individual risk for prostate cancer assessed?
Q34360616Human prostate cancer risk factors
Q91992695Human reproductive behavior, life history, and the Challenge Hypothesis: A 30-year review, retrospective and future directions
Q89049086Human social neuroendocrinology: Review of the rapid effects of testosterone
Q81158385Hyperandrogenism, mediated by obesity and receptor polymorphisms, promotes aggressive epithelial ovarian cancer biology
Q73483127Implications of a polyglutamine tract in the function of the human androgen receptor
Q26825204In situ androgen and estrogen biosynthesis in endometrial cancer: focus on androgen actions and intratumoral production
Q26784181Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action
Q35661289Influence of Low-Level Prenatal Exposure to PCDD/Fs and PCBs on Empathizing, Systemizing and Autistic Traits: Results from the Duisburg Birth Cohort Study.
Q37173763Influence of androgen receptor repeat polymorphisms on personality traits in men
Q42005831Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor
Q34580741Inherited predisposition and breast cancer: modifiers of BRCA1/2-associated breast cancer risk
Q35554127Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression
Q40859984Intracellular processing and toxicity of the truncated androgen receptor: nuclear congophilia-associated cell death
Q38357468Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
Q45227254Investigation of hormone receptor genes in migraine.
Q91564675Is testosterone linked to human aggression? A meta-analytic examination of the relationship between baseline, dynamic, and manipulated testosterone on human aggression
Q34549670Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid
Q36371585Lack of Influence of the Androgen Receptor Gene CAG-Repeat Polymorphism on Clinical and Electrocardiographic Manifestations of the Brugada Syndrome in Man.
Q35828195Lack of association between CAG repeat polymorphism in the androgen receptor gene and the outcome of rheumatoid arthritis treatment with leflunomide
Q58486177Lack of association between androgen receptor CAG polymorphism and familial breast/ovarian cancer
Q43917963Lack of influence of the androgen receptor gene CAG-repeat polymorphism on sex steroid status and bone metabolism in elderly men.
Q80448216Length and somatic mosaicism of CAG and GGN repeats in the androgen receptor gene and the risk of prostate cancer in men with benign prostatic hyperplasia
Q35141431Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo
Q34707086Linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in the African-American population
Q41667978Localization of functional domains in the androgen receptor
Q64092194Long-read single-molecule maps of the functional methylome
Q30496813Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence
Q34055364Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice
Q56227763Male breast cancer
Q28477819Male germ cell-specific RNA binding protein RBMY: a new oncogene explaining male predominance in liver cancer
Q36395111Mechanisms of disease: Polymorphisms of androgen regulatory genes in the development of prostate cancer
Q33976024Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells
Q27008271MicroRNAs that affect prostate cancer: emphasis on prostate cancer in African Americans
Q41887497Microsatellites with macro-influence in ewing sarcoma
Q34160987Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review
Q24545497Mini- and microsatellites
Q47874782Minimum CAG repeat in the human calmodulin-1 gene 5' untranslated region is required for full expression
Q33633160Minireview: the molecular and genomic basis for prostate cancer health disparities
Q34389571Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat
Q35084790Modifiers of risk of hereditary breast and ovarian cancer
Q35024939Molecular Basis of Steroid Action in the Prostate
Q34491450Molecular action of androgen in the normal and neoplastic prostate
Q42725273Molecular analysis of the androgen receptor gene in Hong Kong Chinese infertile men
Q44360255Molecular analysis of the androgen receptor in ten prostate cancer specimens obtained before and after androgen ablation
Q41334556Molecular basis for prostate cancer racial disparities.
Q52538313Molecular basis of androgen receptor diseases.
Q33816588Molecular biology of prostate carcinogenesis
Q28587802Molecular cloning and characterization of a novel mouse macrophage gene that encodes a nuclear protein comprising polyglutamine repeats and interspersing histidines
Q48238211Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia
Q30720277Molecular cloning and functional characterization of the canine androgen receptor
Q58136321Molecular genetics of prostate cancer
Q34566518Molecular markers in sex hormone pathway genes associated with the efficacy of androgen-deprivation therapy for prostate cancer
Q34769413Molecular mechanism of androgen action
Q45327318Molecular mechanisms involving prostate cancer racial disparity
Q37418937Molecular mechanisms involving prostate cancer racial disparity.
Q46101484Molecular organization of 5S rDNAs in Rajidae (Chondrichthyes): Structural features and evolution of piscine 5S rRNA genes and nontranscribed intergenic spacers.
Q28306876Molecular pathology of the androgen receptor in male (in)fertility
Q33962326Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors
Q33965424Multiple Domains Define the Expression and Regulatory Properties of Foxp1 Forkhead Transcriptional Repressors
Q24554443Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins
Q37732743Mutational Analysis of Androgen Receptor (AR) Gene in 46,XY Patients with Ambiguous Genitalia and Normal Testosterone Secretion: Endocrinological Characteristics of Three Patients with AR Gene Mutations
Q40682633Mutations flanking the polyglutamine repeat in the modulatory domain of rat glucocorticoid receptor lead to an increase in affinity for hormone
Q46323996N-terminal polyglutamine-containing fragments inhibit androgen receptor transactivation function
Q36277936Negative association between androgen receptor gene CAG repeat polymorphism and polycystic ovary syndrome? A systematic review and meta-analysis
Q57296926Neuroendocrine stress response is moderated by sex and sex hormone receptor polymorphisms
Q39207785New single nucleotide variation in the promoter region of androgen receptor (AR) gene in hypospadic patients
Q37365761No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene
Q41756427Nuclear receptors: structure, function and involvement in disease
Q57269129Number of X-linked androgen receptor gene CAG repeats and femininity in women
Q48291079Pathogenesis of neurodegenerative diseases associated with expanded glutamine repeats: new answers, new questions.
Q27007098Pathogenic mechanisms and therapeutic strategies in spinobulbar muscular atrophy
Q30405294Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy
Q38238162Perspectives in Pediatric Pathology, Chapter 6. Male Undermasculinization
Q34189642Pharmacogenetics of human androgens and prostatic diseases
Q92625312Physiological and Pathological Androgen Actions in the Ovary
Q35198263Polycystic ovary syndrome woman with heterozygous androgen receptor gene mutation who gave birth to a child with androgen insensitivity syndrome
Q73375094Polyglutamine repeat length influences human androgen receptor/c-Jun mediated transcription
Q34446532Polyglutamine tract expansion of the androgen receptor in a motoneuronal model of spinal and bulbar muscular atrophy.
Q52738092Polyglutamine tracts as modulators of transcriptional activation from yeast to mammals.
Q82458859Polymorphic (CAG)n repeats in the androgen receptor gene: a risk marker for endometriosis and uterine leiomyomas
Q35548715Polymorphic CAG repeats of the androgen receptor gene and rheumatoid arthritis
Q24791382Polymorphic repeat in AIB1 does not alter breast cancer risk
Q57634565Polymorphic repeats in the androgen receptor gene in high-risk sibships
Q39433516Polymorphisms in sex steroid receptors: From gene sequence to behavior.
Q44124773Polymorphisms in the androgen receptor and type II 5 alpha-reductase genes and prostate cancer prognosis
Q36263116Polymorphisms in the vitamin D receptor and the androgen receptor gene associated with the risk of urolithiasis
Q41058628Polymorphisms of the glucocorticoid receptor gene in laboratory and wild rats: steroid binding properties of trinucleotide CAG repeat length variants
Q46729134Preeclampsia and androgen receptor gene CAG repeat length: results from both children and women
Q88646934Preliminary evidence that androgen signaling is correlated with men's everyday language
Q38905604Prostate Cancer in African American Men: The Effect of Androgens and microRNAs on Epidermal Growth Factor Signaling.
Q35547017Prostate Development and Carcinogenesis
Q38683379Prostate cancer in men of African origin.
Q28508802Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium
Q33812889Racial differences in the androgen/androgen receptor pathway in prostate cancer.
Q57943193Rapid and accurate determination of (CAG)n repeats in the androgen receptor gene using polymerase chain reaction and automated fragment analysis
Q64055629Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms
Q36287950Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men.
Q77229014Reconstitution of the N-terminal transcription activation function of human mineralocorticoid receptor in a defective human glucocorticoid receptor
Q46683533Reduced CAG repeats length in androgen receptor gene is associated with violent criminal behavior
Q28611237Regulation of androgen action
Q43759819Relationship between expansion of the CAG repeat in exon 1 of the androgen receptor gene and idiopathic male infertility
Q33621461Relationships among androgen receptor CAG repeat polymorphism, sex hormones and penile length in Han adult men from China: a cross-sectional study
Q38181427Relevance of genetic investigation in male infertility.
Q36277189Repeat instability: mechanisms of dynamic mutations
Q37361212Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing.
Q34219464Revisiting the role of antiandrogen strategies in ovarian cancer
Q91791514Role for androgens in determination of ovarian fate in the common snapping turtle, Chelydra serpentina
Q90442504Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review)
Q33851770Role of androgen receptor CAG repeat polymorphism and X-inactivation in the manifestation of recurrent spontaneous abortions in Indian women
Q21195191Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
Q40951040Role of vitamin D levels and vitamin D supplementation on bone mineral density in Klinefelter syndrome.
Q33675144Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in men
Q34630761Second to fourth digit ratio: a predictor of adult penile length
Q85040440Selected estrogen receptor 1 and androgen receptor gene polymorphisms in relation to risk of breast cancer and fibrocystic breast conditions among Chinese women
Q54290846Semen quality is influenced by androgen receptor and aromatase gene synergism.
Q37397526Serum organochlorine pesticide residues and risk of testicular germ cell carcinoma: a population-based case-control study
Q46555023Serum resistin and polymorphisms of androgen receptor GAGn and GGNn and aromatase TTTAn
Q39525050Serum testosterone levels in African-American and white men undergoing prostate biopsy
Q38878236Sex Hormones and Cognition: Neuroendocrine Influences on Memory and Learning
Q57316581Sex hormone receptor gene variation associated with phenotype in male hypertrophic cardiomyopathy patients
Q34772485Sex hormones and liver cancer
Q36737983Sex steroid-related candidate genes in psychiatric disorders.
Q90288514Sex-Specific Associations of Androgen Receptor CAG Trinucleotide Repeat Length and of Raloxifene Treatment with Testosterone Levels and Perceived Stress in Schizophrenia
Q40092714Short androgen receptor poly-glutamine-promoted endometrial cancer is associated with benzo[a]pyrene-mediated aryl hydrocarbon receptor activation.
Q46145087Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome
Q34102095Significance of the polyglutamine tract polymorphism in the androgen receptor
Q34738348Simple sequence repeats as a source of quantitative genetic variation
Q33273791Simple sequence repeats in zebra finch (Taeniopygia guttata) expressed sequence tags: a new resource for evolutionary genetic studies of passerines
Q36469802Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy
Q46619826Soccer players awarded one or more red cards exhibit lower 2D:4D ratios
Q61449459Somatic alterations of the androgen receptor CAG repeat in human colon cancer delineate a novel mutation pathway independent of microsatellite instability
Q34603312Somatic mutations at the trinucleotide repeats of androgen receptor gene in male hepatocellular carcinoma
Q34488237South Indian men with reduced CAG repeat length in the androgen receptor gene have an increased risk of prostate cancer
Q57826122Spatial Abilities in Prepubertal Intellectually Gifted Boys and Genetic Polymorphisms Related to Testosterone Metabolism
Q34631186Steroid receptors in human breast tumorigenesis and breast cancer progression
Q36714838StuI polymorphism on the androgen receptor gene is associated with recurrent spontaneous abortion.
Q46816648Synergistic effect of follicle-stimulating hormone receptor and androgen receptor gene variants on semen quality
Q33938808Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study
Q77223275Tandem CAG repeats of the androgen receptor gene and prostate cancer risk in black and white men
Q37853838Testicular germ cell tumours: predisposition genes and the male germ cell niche.
Q47375701Testosterone administration does not affect men's rejections of low ultimatum game offers or aggressive mood
Q47641814Testosterone and androgen receptor gene polymorphism are associated with confidence and competitiveness in men.
Q35064997Testosterone deficiency and mood in aging men: pathogenic and therapeutic interactions
Q43728711Testosterone level, androgen receptor polymorphism, and depressive symptoms in middle-aged men.
Q35684578Testosterone metabolism, dose-response relationships and receptor polymorphisms: selected pharmacological/toxicological considerations on benefits versus risks of testosterone therapy in men.
Q44173664Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
Q36303823Testosterone replacement therapy for late onset hypogonadism: what is the risk of inducing prostate cancer?
Q24810265The AIB1 glutamine repeat polymorphism is not associated with risk of breast cancer before age 40 years in Australian women
Q75204922The CAG repeat polymorphism in the androgen receptor gene (AR) and its relationship to head and neck cancer
Q43917960The CAG repeat polymorphism in the androgen receptor gene affects bone density and bone metabolism in healthy males
Q34483532The CAG repeat polymorphism in the androgen receptor gene modifies the risk for hypospadias in Caucasians
Q39484078The CAG repeat within the androgen receptor gene and benign prostatic hyperplasia
Q36085009The CAG repeat within the androgen receptor gene and its relationship to prostate cancer
Q45269025The CAG repeats in exon 1 of the androgen receptor gene are significantly longer in endometrial cancer patients.
Q35676497The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR-gamma.
Q28553212The Presence of Clitoromegaly in the Nonclassical Form of 21-Hydroxylase Deficiency Could Be Partially Modulated by the CAG Polymorphic Tract of the Androgen Receptor Gene
Q89963927The Relation Between Steroid Secretion Patterns and the Androgen Receptor Gene Polymorphism on Physical Health and Psychological Well-Being-Longitudinal Findings From the Men's Health 40+ Study
Q64245953The Role of Androgen Receptor Signaling in Ovarian Cancer
Q34096288The Role of Androgens in Normal and Malignant Breast Tissue
Q37603742The Second-to-Fourth Digit Ratio in Cryptorchidism: A Case-Control Study
Q37714440The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine Disease
Q42562784The androgen receptor CAG and GGN repeat polymorphisms and prostate cancer susceptibility in African-American men: results from the Flint Men's Health Study
Q77753509The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer
Q24797305The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
Q34772530The androgen receptor CAG repeat: a modifier of carcinogenesis?
Q73549450The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer
Q34395691The androgen receptor gene and its influence on the development and progression of prostate cancer
Q37074481The androgen receptor's CAG/glutamine tract in mouse models of neurological disease and cancer.
Q35193278The androgen receptor: structure, mutations, and antiandrogens
Q36236084The androgen receptor: unlocking the secrets of its unique transactivation domain
Q34145721The association between androgen receptor gene CAG polymorphism and polycystic ovary syndrome: a case-control study and meta-analysis
Q50133280The association between glutamine repeats in the androgen receptor gene and personality traits in dromedary camel (Camelus dromedarius).
Q37204533The biological effects of simple tandem repeats: lessons from the repeat expansion diseases
Q44529187The coactivator p/CIP/SRC-3 facilitates retinoic acid receptor signaling via recruitment of GCN5.
Q57632581The degree of external genitalia virilization in girls with 21-hydroxylase deficiency appears to be influenced by the CAG repeats in the androgen receptor gene
Q46118080The effect of CAG repeat length polymorphism in the murine glucocorticoid receptor on transactivation potential
Q55162411The effect of CAG repeats length on differences in hirsutism among healthy Israeli women of different ethnicities.
Q50135033The endocrinology of human caregiving and its intergenerational transmission
Q35123242The epidemiology of prostate cancer
Q40690270The interaction of serum testosterone levels and androgen receptor CAG repeat polymorphism on the risk of erectile dysfunction in aging Taiwanese men.
Q37000744The latest options and future agents for treating male hypogonadism
Q39932932The modulating effect of the androgen receptor on craving in alcohol withdrawal of men is partially mediated by leptin.
Q38614574The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms
Q48368882The number of CAG and GGN triplet repeats in the Androgen Receptor gene exert combinatorial effect on hormonal and sperm parameters in young men.
Q46390903The origins of extraversion: joint effects of facultative calibration and genetic polymorphism
Q38901971The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation
Q35750034The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study
Q38003702The pharmacogenomics of sex hormone metabolism: breast cancer risk in menopausal hormone therapy
Q47097766The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity
Q74555292The polymorphic CAG repeat in the androgen receptor gene in Jewish Israeli women with endometrial carcinoma
Q59238477The polymorphic CAG repeat of the androgen receptor gene: a potential role in breast cancer in women over 40
Q31159652The relation of the XbaI and PvuII polymorphisms of the estrogen receptor gene and the CAG repeat polymorphism of the androgen receptor gene to peak bone mass and bone turnover rate among young healthy men.
Q45249317The relationship between CAG repeat length polymorphism and infertility in Southern Chinese Han women
Q42140450The relationship between anogenital distance and the androgen receptor CAG repeat length.
Q81612086The relationship between the androgen receptor CAG repeat polymorphism length and the response to intermittent androgen suppression therapy for advanced prostate cancer
Q26992207The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humans
Q37660904The role of SRC-3 in human breast cancer
Q24792607The role of X-chromosome inactivation in female predisposition to autoimmunity
Q36760784The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS
Q24803613The role of androgens and polymorphisms in the androgen receptor in the epidemiology of breast cancer
Q34930044The role of androgens and the androgen receptor in prostate cancer
Q37145218The role of testosterone in the pathogenesis of prostate cancer
Q56115438The second to fourth digit ratio and variation in the androgen receptor gene
Q36274375Total testosterone, androgen receptor polymorphism, and depressive symptoms in young black and white men: the CARDIA Male Hormone Study
Q41169482Transcriptional activation and transient expression of the human androgen receptor
Q34001953Transcriptional dysregulation in Huntington's disease
Q35113556Transcriptional intermediary factor 1alpha mediates physical interaction and functional synergy between the coactivator-associated arginine methyltransferase 1 and glucocorticoid receptor-interacting protein 1 nuclear receptor coactivators
Q73428107Trinucleotide (CAG) repeat polymorphisms in the androgen receptor gene: molecular markers of risk for male infertility
Q57190619Trinucleotide Repeat Expansion Diseases, RNAi, and Cancer
Q35025253Trinucleotide repeat disease. The androgen receptor in spinal and bulbar muscular atrophy
Q40959214Trinucleotide repeat expansion and human disease
Q38551802Trinucleotide repeat expansions in human breast cancer-susceptibility genes: relevant targets for aspirin chemoprevention?
Q103025524Uncovering Mitochondrial Determinants of Racial Disparities in Ovarian Cancer
Q43650580Undermasculinized genitalia in a boy with an abnormally expanded CAG repeat length in the androgen receptor gene.
Q37878799Understanding polycystic ovarian syndrome pathogenesis: an updated of its genetic aspects
Q34751856Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers
Q49101957Variation in CAG repeat length of the androgen receptor gene predicts variables associated with intrasexual competitiveness in human males
Q30570172Variation in candidate genes CLOCK and ADCYAP1 does not consistently predict differences in migratory behavior in the songbird genus Junco.
Q33576486Variation in the androgen receptor gene exon 1 CAG repeat correlates with manifestations of autoimmunity in women with lupus
Q61051650X chromosome inactivation in cervical cancer patients

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