Transcriptional activation and nuclear targeting signals of the human androgen receptor.

scientific article

Transcriptional activation and nuclear targeting signals of the human androgen receptor. is …
instance of (P31):
scholarly articleQ13442814

External links are
P698PubMed publication ID1985913

P2093author name stringWilson EM
Sar M
French FS
Simental JA
Lane MV
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)510-518
P577publication date1991-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleTranscriptional activation and nuclear targeting signals of the human androgen receptor
P478volume266

Reverse relations

cites work (P2860)
Q35998094A Recurrent Germline Mutation in the 5'UTR of the Androgen Receptor Causes Complete Androgen Insensitivity by Activating Aberrant uORF Translation
Q34550256A Tale of Two Signals: AR and WNT in Development and Tumorigenesis of Prostate and Mammary Gland.
Q37900501A new trick of an old molecule: androgen receptor splice variants taking the stage?!
Q28116222A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
Q37359901A novel missense mutation in the amino-terminal domain of the human androgen receptor gene in a family with partial androgen insensitivity syndrome causes reduced efficiency of protein translation
Q26747094A sting in the tail: the N-terminal domain of the androgen receptor as a drug target
Q30748653ARA67/PAT1 functions as a repressor to suppress androgen receptor transactivation
Q36681464Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation
Q38718942An Amyloidogenic Sequence at the N-Terminus of the Androgen Receptor Impacts Polyglutamine Aggregation.
Q36966859An androgen receptor N-terminal domain antagonist for treating prostate cancer.
Q37165574An imaging agent to detect androgen receptor and its active splice variants in prostate cancer
Q39499483Analysis of interdomain interactions of the androgen receptor
Q58789891Androgen Action in the Ovary
Q37636067Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia.
Q29036974Androgen Receptor Exon 1 Mutation Causes Androgen Insensitivity by Creating Phosphorylation Site and Inhibiting Melanoma Antigen-A11 Activation of NH2- and Carboxyl-terminal Interaction-dependent Transactivation
Q39227656Androgen Signaling in Prostate Cancer
Q40944089Androgen effects on the solubility and conformational change of the androgen receptor in baculovirus expression system
Q38946793Androgen receptor and miR-206 regulation in prostate cancer.
Q35611734Androgen receptor decoy molecules block the growth of prostate cancer
Q37050377Androgen receptor drives transcription of rat PACAP in gonadotrope cells
Q42738421Androgen receptor gene mutation, rearrangement, polymorphism.
Q37104443Androgen receptor gene mutations in human prostate cancer
Q35742116Androgen receptor in hepatocarcinogenesis: Recent developments and perspectives
Q36237251Androgen receptor regulation by histone methyltransferase Suppressor of variegation 3-9 homolog 2 and Melanoma antigen-A11.
Q35183663Androgen receptor signaling in prostate cancer development and progression
Q42573875Androgen receptor signalling in prostate cancer: the functional consequences of acetylation
Q92002903Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
Q38865487Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic.
Q36063723Androgen receptor: structure, role in prostate cancer and drug discovery
Q36326556Androgen receptors, sex behavior, and aggression
Q55357541Androgen-Induced Immunosuppression.
Q57800002Androgen-dependent immune modulation in parasitic infection
Q33292178Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription
Q34049353Binding-folding induced regulation of AF1 transactivation domain of the glucocorticoid receptor by a cofactor that binds to its DNA binding domain
Q30500293Calmodulin protects androgen receptor from calpain-mediated breakdown in prostate cancer cells
Q36128635Cell Models for the Study of Sex Steroid Hormone Neurobiology.
Q36218806Cell-based assays for screening androgen receptor ligands
Q41083443Cell-specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors
Q34299330Characterization of androgen receptor structure and nucleocytoplasmic shuttling of the rice field eel.
Q42735199Characterization of karyopherins in androgen receptor intracellular trafficking in the yeast model
Q28543404Characterization of niphatenones that inhibit androgen receptor N-terminal domain
Q24653761Characterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems
Q35226136Codon reiteration and the evolution of proteins
Q33893810Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation
Q34775572Constitutive activity of the androgen receptor
Q24657742Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily
Q39894032Cytoplasmic localization of the androgen receptor is independent of calreticulin
Q37183952Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy
Q35063026Delineation of a small region within the major transactivation domain of the human glucocorticoid receptor that mediates transactivation of gene expression
Q34558010Development of selective androgen receptor modulators (SARMs).
Q36290667Dexamethasone negatively regulates the activity of a chimeric dihydrofolate reductase/glucocorticoid receptor protein
Q43222841Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres
Q34137546Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer
Q24652929Epidermal-growth-factor-dependent phosphorylation and ubiquitinylation of MAGE-11 regulates its interaction with the androgen receptor
Q37482979Evolutionary history and functional characterization of androgen receptor genes in jawed vertebrates.
Q47825253Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Q34172728Expression of the nuclear transport protein importin ß-1 and its association with the neurokinin 3 receptor in the rat hypothalamus following acute hyperosmotic challenge
Q34580343FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.
Q29040033Gain in Transcriptional Activity by Primate-specific Coevolution of Melanoma Antigen-A11 and Its Interaction Site in Androgen Receptor
Q40958215Genes involved in testicular development and function
Q37206980Genetic Association Between Androgen Receptor Gene CAG Repeat Length Polymorphism and Male Infertility: A Meta-Analysis
Q47177866Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival
Q21284425Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor
Q33823680Hey1, a mediator of notch signaling, is an androgen receptor corepressor
Q39429490Hsp90 inhibitor 17-AAG inhibits progression of LuCaP35 xenograft prostate tumors to castration resistance.
Q40227114Human androgen receptor expressed in HeLa cells activates transcription in vitro
Q24329102Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription
Q35311828Identification of androgen receptor protein and 5alpha-reductase mRNA in human ocular tissues
Q38314229In vitro translation of androgen receptor cRNA results in an activated androgen receptor protein
Q37281115In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice
Q97883479Influence of Androgens on Immunity to Self and Foreign: Effects on Immunity and Cancer
Q47699658Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone.
Q24654156Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF
Q26853572Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization
Q33632245Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling
Q24633369Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages
Q24556963Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction
Q35007914Melanoma antigen gene protein-A11 (MAGE-11) F-box links the androgen receptor NH2-terminal transactivation domain to p160 coactivators
Q34313140Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers
Q27646416Modulation of Androgen Receptor Activation Function 2 by Testosterone and Dihydrotestosterone
Q41205937Molecular determinants of sexual differentiation
Q40829556Molecular genetics of human androgen insensitivity
Q41886996Molecular processes leading to aberrant androgen receptor signaling and castration resistance in prostate cancer
Q41466777Muscle-bound? A tissue-selective nonsteroidal androgen receptor modulator
Q33595072Mutations of the androgen receptor gene identified in perineal hypospadias
Q36803788Natural disordered sequences in the amino terminal domain of nuclear receptors: lessons from the androgen and glucocorticoid receptors
Q38745981New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer.
Q41536310Nuclear import of the human androgen receptor
Q40394004Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins
Q31081182PATHLOGIC-S: a scalable Boolean framework for modelling cellular signalling
Q27007098Pathogenic mechanisms and therapeutic strategies in spinobulbar muscular atrophy
Q33623221Phenotypic variation and detection of carrier status in the partial androgen insensitivity syndrome
Q36139948Post-translational Down-regulation of Melanoma Antigen-A11 (MAGE-A11) by Human p14-ARF Tumor Suppressor
Q37112738Proto-oncogene activity of melanoma antigen-A11 (MAGE-A11) regulates retinoblastoma-related p107 and E2F1 proteins
Q24298419Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors
Q64955772SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA.
Q30352713SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells.
Q24645579Selective androgen receptor modulators in preclinical and clinical development
Q97533909Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer
Q28081545Sex-based differences in skeletal muscle kinetics and fiber-type composition
Q90194958Should Tumor Infiltrating Lymphocytes, Androgen Receptor, and FOXA1 Expression Predict the Clinical Outcome in Triple Negative Breast Cancer Patients?
Q30435809Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor
Q37338900Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.
Q36777961Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer
Q28910351Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.
Q24337882Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription
Q33810134Small molecule inhibitors targeting the "achilles' heel" of androgen receptor activity
Q38289592Specificity of simple hormone response elements in androgen regulated genes
Q40393976Splinkerettes--improved vectorettes for greater efficiency in PCR walking.
Q37576700Structural and functional relationships of the steroid hormone receptors' N-terminal transactivation domain
Q35417636Structural features discriminate androgen receptor N/C terminal and coactivator interactions
Q24537137Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations
Q36415787TM4SF3 and AR: A Nuclear Complex that Stabilizes Both Proteins
Q38114780Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
Q37496652Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer.
Q37301854Testosterone conversion blockade increases breathing stability in healthy men during NREM sleep
Q36915833Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages
Q24554379The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1
Q34022799The N-terminal domain of the androgen receptor drives its nuclear localization in castration-resistant prostate cancer cells
Q24606948The androgen receptor gene mutations database
Q37074752The androgen receptor in hormone-refractory prostate cancer
Q34145721The association between androgen receptor gene CAG polymorphism and polycystic ovary syndrome: a case-control study and meta-analysis
Q35010014The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
Q25257485The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells
Q24532004The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions
Q34771755Transcriptional repression of the alpha-subunit gene by androgen receptor occurs independently of DNA binding but requires the DNA-binding and ligand-binding domains of the receptor
Q33967239Transcriptional synergy between melanoma antigen gene protein-A11 (MAGE-11) and p300 in androgen receptor signaling
Q24616410Two mutations in the hormone binding domain of the vitamin D receptor cause tissue resistance to 1,25 dihydroxyvitamin D3
Q33837335Two panels of steroid receptor luciferase reporter cell lines for compound profiling.
Q36454548Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival
Q73121984c-Jun targets amino terminus of androgen receptor in regulating androgen-responsive transcription

Search more.