| scholarly article | Q13442814 |
| P2093 | author name string | Jorma J Palvimo | |
| Daniel Gioeli | |||
| Bryce M Paschal | |||
| Harri Makkonen | |||
| Miia M Rytinki | |||
| Sanna Kaikkonen | |||
| Tiina Jääskeläinen | |||
| Ulla Karvonen | |||
| P2860 | cites work | Differential regulation of sentrinized proteins by a novel sentrin-specific protease | Q22011173 |
| Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor | Q24315950 | ||
| A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2 | Q24317523 | ||
| Negative modulation of androgen receptor transcriptional activity by Daxx | Q24318233 | ||
| Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription | Q24329102 | ||
| SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1 | Q24337470 | ||
| Transcription factor Sp3 is silenced through SUMO modification by PIAS1 | Q24534887 | ||
| Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators | Q54027019 | ||
| Interaction of androgen receptors with androgen response element in intact cells. Roles of amino- and carboxyl-terminal regions and the ligand | Q73427536 | ||
| The presence of a transcription activation function in the hormone‐binding domain of androgen receptor is revealed by studies in yeast cells | Q73585548 | ||
| Androgen receptor regulates nuclear trafficking and nuclear domain residency of corepressor HDAC7 in a ligand-dependent fashion | Q79964099 | ||
| The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice | Q81571103 | ||
| The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase | Q24534918 | ||
| SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1 | Q24563640 | ||
| Role of desumoylation in the development of prostate cancer | Q24676101 | ||
| SUSP1 antagonizes formation of highly SUMO2/3-conjugated species | Q24682911 | ||
| Chemistry and structural biology of androgen receptor | Q24685498 | ||
| Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma | Q24685818 | ||
| Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. | Q27863703 | ||
| Characterization of the Localization and Proteolytic Activity of the SUMO-specific Protease, SENP1 | Q27863778 | ||
| Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. | Q27863917 | ||
| The SUMO-specific protease SENP5 is required for cell division | Q27863924 | ||
| Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins | Q27936336 | ||
| The nucleoporin RanBP2 has SUMO1 E3 ligase activity | Q28115025 | ||
| Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription | Q28138255 | ||
| ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation | Q28140379 | ||
| Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor | Q28216750 | ||
| SUMO: a history of modification | Q28243325 | ||
| Concepts in sumoylation: a decade on | Q28257220 | ||
| PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription | Q28258345 | ||
| A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation | Q28274983 | ||
| Proteasome-independent functions of ubiquitin in endocytosis and signaling | Q28282959 | ||
| Mutual transcriptional interference between RelA and androgen receptor | Q28289361 | ||
| Modification in reverse: the SUMO proteases | Q28302162 | ||
| Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. | Q28589576 | ||
| A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma | Q28593737 | ||
| DNA binding domains in diverse nuclear receptors function as nuclear export signals. | Q30308287 | ||
| Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites | Q30309352 | ||
| Nuclear transport of steroid hormone receptors | Q30436547 | ||
| Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization | Q30438663 | ||
| Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactions | Q30443046 | ||
| Subcellular localization modulates activation function 1 domain phosphorylation in the androgen receptor | Q30443883 | ||
| Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells | Q33295020 | ||
| Cancer proliferation gene discovery through functional genomics. | Q33317743 | ||
| Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif | Q33643260 | ||
| ??? | Q28204045 | ||
| p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation | Q33899255 | ||
| A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs | Q33900867 | ||
| Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex | Q34007618 | ||
| Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation | Q34086058 | ||
| Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function | Q34125103 | ||
| The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1. | Q34132954 | ||
| PDSM, a motif for phosphorylation-dependent SUMO modification | Q34248164 | ||
| Steroid receptor phosphorylation: a key modulator of multiple receptor functions | Q34632607 | ||
| Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy | Q34791472 | ||
| Transcriptional activation and nuclear targeting signals of the human androgen receptor. | Q35009652 | ||
| Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). | Q35836715 | ||
| Intranuclear organization and function of the androgen receptor | Q35935836 | ||
| Controlling nuclear receptors: the circular logic of cofactor cycles | Q36163600 | ||
| Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis | Q36309725 | ||
| Post-translational modifications of steroid receptors | Q36584226 | ||
| Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer | Q36777961 | ||
| SUMOrganization of the nucleus | Q36805459 | ||
| SUMO-specific proteases: a twist in the tail | Q36927821 | ||
| Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation | Q36931106 | ||
| Androgen signaling and its interactions with other signaling pathways in prostate cancer | Q37002961 | ||
| SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX. | Q37073920 | ||
| A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy | Q39454884 | ||
| PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. | Q39695522 | ||
| Identification of ETS-like transcription factor 4 as a novel androgen receptor target in prostate cancer cells. | Q39983681 | ||
| Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells | Q40068850 | ||
| Phosphorylation-dependent sumoylation of estrogen-related receptor alpha1. | Q40097998 | ||
| Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. | Q40125826 | ||
| The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor | Q40136444 | ||
| PIASxalpha differentially regulates the amplitudes of transcriptional responses following activation of the ERK and p38 MAPK pathways | Q40277497 | ||
| SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin | Q40415650 | ||
| SUMO-1 promotes association of SNURF (RNF4) with PML nuclear bodies. | Q40459430 | ||
| The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor. | Q40863086 | ||
| Nuclear import of the human androgen receptor | Q41536310 | ||
| Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene | Q41580505 | ||
| Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element. | Q42484983 | ||
| Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor | Q43002306 | ||
| The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression | Q44061992 | ||
| Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts | Q44690065 | ||
| Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements | Q44805586 | ||
| SUMO promotes HDAC-mediated transcriptional repression | Q48017954 | ||
| Potentiation of glucocorticoid receptor transcriptional activity by sumoylation | Q51843778 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | prostate cancer | Q181257 |
| protein sumoylation | Q3503705 | ||
| P304 | page(s) | 292-307 | |
| P577 | publication date | 2008-12-30 | |
| P1433 | published in | Molecular Endocrinology | Q3319475 |
| P1476 | title | SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells. | |
| P478 | volume | 23 |
| Q42715509 | 2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation |
| Q26864235 | Advances in the development of SUMO specific protease (SENP) inhibitors |
| Q39499470 | Analysis of Androgen Receptor SUMOylation |
| Q39507379 | Androgen receptor abnormalities in castration-recurrent prostate cancer |
| Q28678204 | Assays for Investigating deSUMOylation Enzymes |
| Q92283236 | Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs) |
| Q41874525 | Conformational flexibility and changes underlying activation of the SUMO-specific protease SENP1 by remote substrate binding |
| Q99571280 | Constitutively active androgen receptor supports the metastatic phenotype of endocrine-resistant hormone receptor-positive breast cancer |
| Q34206915 | Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation |
| Q44642784 | Differential expression and cellular localization of novel isoforms of the tendon biomarker tenomodulin |
| Q30405382 | Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease. |
| Q37002382 | Downregulation of SENP1 inhibits cell proliferation, migration and promotes apoptosis in human glioma cells |
| Q39297900 | Dynamic SUMOylation Is Linked to the Activity Cycles of Androgen Receptor in the Cell Nucleus |
| Q38256197 | Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review. |
| Q37954599 | Human Pathogens and the Host Cell SUMOylation System |
| Q37341772 | Identification and Characterization of a New Chemotype of Noncovalent SENP Inhibitors |
| Q24337533 | Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation |
| Q61795920 | Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction |
| Q24339376 | Lens epithelium‐derived growth factor deSumoylation by Sumo‐specific protease‐1 regulates its transcriptional activation of small heat shock protein and the cellular response |
| Q52760987 | MiR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer |
| Q37055715 | Molecular pathogenesis and progression of prostate cancer |
| Q36826106 | Nuclear Receptor Coactivators: Structural and Functional Biochemistry |
| Q38965675 | Nuclear mobility and activity of FOXA1 with androgen receptor are regulated by SUMOylation |
| Q35786826 | Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer |
| Q33823702 | Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer |
| Q27007098 | Pathogenic mechanisms and therapeutic strategies in spinobulbar muscular atrophy |
| Q35842790 | Post-Translational Modifications of Nuclear Receptors and Human Disease |
| Q30454054 | Post-translational modification of the androgen receptor |
| Q27010251 | Post-translational modifications of the progesterone receptors |
| Q37092022 | Posttranslational Modification of the Androgen Receptor in Prostate Cancer |
| Q39642888 | Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor. |
| Q39236149 | Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells. |
| Q50053066 | RAS GTPases are modified by SUMOylation. |
| Q38032833 | Regulation of the androgen receptor by post-translational modifications |
| Q34416164 | Role of the BCA2 Ubiquitin E3 Ligase in Hormone Responsive Breast Cancer |
| Q35380380 | Roles of ubiquitination and SUMOylation on prostate cancer: mechanisms and clinical implications |
| Q92859711 | SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T |
| Q38894093 | SENP1 regulates cell migration and invasion in neuroblastoma |
| Q33624675 | SUMO-Specific Cysteine Protease 1 Promotes Epithelial Mesenchymal Transition of Prostate Cancer Cells via Regulating SMAD4 deSUMOylation |
| Q39325271 | SUMO-specific protease 1 promotes prostate cancer progression and metastasis |
| Q38956991 | SUMO-specific protease 1 regulates pancreatic cancer cell proliferation and invasion by targeting MMP-9. |
| Q28594151 | SUMO-specific protease 2 in Mdm2-mediated regulation of p53 |
| Q36177650 | SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein. |
| Q38979379 | SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner. |
| Q41941328 | SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor |
| Q52584573 | Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets |
| Q36466624 | Sumoylation of SAE2 C Terminus Regulates SAE Nuclear Localization |
| Q26866679 | Sumoylation of critical proteins in amyotrophic lateral sclerosis: emerging pathways of pathogenesis |
| Q33769417 | Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization |
| Q42759370 | The In Vivo Functions of Desumoylating Enzymes |
| Q33649507 | The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer |
| Q36225738 | The in vivo role of androgen receptor SUMOylation as revealed by androgen insensitivity syndrome and prostate cancer mutations targeting the proline/glycine residues of synergy control motifs. |
| Q35706611 | The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion |
| Q27667579 | The role of Co2+in the crystallization of human SENP1 and comments on the limitations of automated refinement protocols |
| Q37660872 | Transcriptional repression of estrogen receptor α signaling by SENP2 in breast cancer cells. |
| Q28484018 | Triptolide Inhibits the Proliferation of Prostate Cancer Cells and Down-Regulates SUMO-Specific Protease 1 Expression |
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