| scholarly article | Q13442814 |
| P50 | author | Laura R Barkley | Q56543925 |
| P2093 | author name string | Cyrus Vaziri | |
| Ying Zou | |||
| Ihn Young Song | |||
| P2860 | cites work | The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis | Q24291114 |
| Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. | Q24533333 | ||
| Cdc6 protein causes premature entry into S phase in a mammalian cell-free system | Q24533451 | ||
| PSF1 is essential for early embryogenesis in mice | Q24535004 | ||
| Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae | Q24535011 | ||
| Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks | Q24543916 | ||
| Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest | Q24544219 | ||
| Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase | Q24548452 | ||
| Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint | Q24564395 | ||
| Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 | Q24610106 | ||
| GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast | Q24672450 | ||
| Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance | Q24672646 | ||
| Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication | Q24680096 | ||
| Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication | Q24685710 | ||
| Structure of the human GINS complex and its assembly and functional interface in replication initiation | Q27644373 | ||
| CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast | Q27932774 | ||
| Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin | Q27933399 | ||
| GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks | Q27934889 | ||
| Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. | Q27935340 | ||
| DNA replication in eukaryotic cells | Q28131747 | ||
| Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha | Q28140031 | ||
| MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways | Q28212514 | ||
| A key role for the GINS complex at DNA replication forks | Q28299814 | ||
| ATR disruption leads to chromosomal fragmentation and early embryonic lethality | Q28591433 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation | Q30437070 | ||
| Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage | Q31160033 | ||
| ATR and ATM regulate the timing of DNA replication origin firing | Q33204272 | ||
| Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome | Q33217275 | ||
| The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts | Q33254833 | ||
| Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation | Q34097202 | ||
| A p53-dependent checkpoint pathway prevents rereplication | Q34533175 | ||
| The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism | Q34557750 | ||
| Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase | Q34559103 | ||
| Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin | Q34574600 | ||
| The functional role of Cdc6 in S-G2/M in mammalian cells | Q34590385 | ||
| An oncogene-induced DNA damage model for cancer development | Q34759268 | ||
| Cdc45-MCM-GINS, a new power player for DNA replication. | Q35024585 | ||
| A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication | Q35965009 | ||
| DNA replication and progression through S phase | Q36101749 | ||
| gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes | Q36418967 | ||
| UV-B-induced cell cycle perturbations, micronucleus induction, and modulation by caffeine in human keratinocytes | Q36797206 | ||
| Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication | Q39576309 | ||
| Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma. | Q40389546 | ||
| Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. | Q40501657 | ||
| Kinetochore immunofluorescence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts | Q41375691 | ||
| The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase | Q41790624 | ||
| Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. | Q43895501 | ||
| Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. | Q46949073 | ||
| A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. | Q52575410 | ||
| Knockdown of human MCM10 activates G2 checkpoint pathway. | Q53517019 | ||
| Knockdown of human MCM10 exhibits delayed and incomplete chromosome replication. | Q53517025 | ||
| Application of antikinetochore antibody staining (CREST staining) to micronuclei in erythrocytes induced in vivo | Q68354705 | ||
| Differentiation of micronuclei in mouse bone marrow cells: a comparison between CREST staining and fluorescent in situ hybridization with centromeric and telomeric DNA probes | Q72825916 | ||
| Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells | Q79286227 | ||
| ATM and ATR check in on origins: a dynamic model for origin selection and activation | Q81284851 | ||
| ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation | Q95721661 | ||
| P433 | issue | 10 | |
| P304 | page(s) | 1577-1588 | |
| P577 | publication date | 2009-05-23 | |
| P1433 | published in | Cell Cycle | Q1254166 |
| P1476 | title | Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells | |
| P478 | volume | 8 |
| Q42366169 | "Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma |
| Q91800201 | Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism |
| Q37334072 | Effect of GINS2 on proliferation and apoptosis in leukemic cell line |
| Q91276831 | GINS2 promotes cell proliferation and inhibits cell apoptosis in thyroid cancer by regulating CITED2 and LOXL2 |
| Q90259868 | GINS2 regulates cell proliferation and apoptosis in human epithelial ovarian cancer |
| Q42290206 | Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency |
| Q34311881 | Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2 |
| Q34972318 | PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention. |
| Q34571700 | Partner of Sld five 3: a potential prognostic biomarker for colorectal cancer |
| Q53062576 | Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast. |
| Q47614165 | Sld5 Ensures Centrosomal Resistance to Congression Forces by Preserving Centriolar Satellites |
| Q37673223 | Structure and function of the GINS complex, a key component of the eukaryotic replisome |
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