Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

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Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1017905987
P356DOI10.1038/NATURE05432
P8608Fatcat IDrelease_hjmpqnv3qnhqncqou7etjapllm
P3181OpenCitations bibliographic resource ID890419
P698PubMed publication ID17167417

P50authorJohn Francis Xavier DiffleyQ21165804
Philip ZegermanQ57321373
P2093author name stringJohn F X Diffley
P2860cites workSld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeQ24535011
CDK phosphorylation of Drc1 regulates DNA replication in fission yeast.Q54313341
CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during MitosisQ60482292
Preventing re-replication of chromosomal DNA.Q24653685
mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7pQ24678671
A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycleQ27931253
A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11Q27931893
CLB5-dependent activation of late replication origins in S. cerevisiae.Q27932788
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complexQ27933305
Cdc7 is required throughout the yeast S phase to activate replication origins.Q27936667
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleusQ27937350
DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiaeQ27938942
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiaeQ27939221
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiaeQ27939590
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replicationQ27939757
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeastQ27940196
Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase.Q27940280
BRCT domain-containing protein TopBP1 functions in DNA replication and damage responseQ28200771
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replicationQ28209282
S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeastQ28216395
Interactions between BRCT repeats and phosphoproteins: tangled up in twoQ28289371
Targets of the cyclin-dependent kinase Cdk1Q29616479
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phaseQ29618007
CLB5: a novel B cyclin from budding yeast with a role in S phaseQ29618258
Two steps in the assembly of complexes at yeast replication origins in vivoQ29618323
An essential G1 function for cyclin-like proteins in yeastQ29620232
Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndromeQ33217275
Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.Q33775448
Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.Q33958598
Regulation of early events in chromosome replicationQ34349937
The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at StartQ37439494
Cell cycle regulation of DNA replication initiator factor Dbf4pQ38324665
Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complexQ39450177
Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replicationQ39576309
The Cdc7 protein kinase is required for origin firing during S phaseQ40442830
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replicationQ41491045
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha.Q42649298
Linkage of replication to start by the Cdk inhibitor Sic1.Q51114804
P433issue7125
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
Sld2p YKL108WQ27549320
Sld3p YGL113WQ27550166
Protein kinase activating protein DPB11 YJL090CQ27551215
P304page(s)281-285
P577publication date2006-12-13
P1433published inNatureQ180445
P1476titlePhosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
P478volume445

Reverse relations

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Q57053683Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms
Q24297901Treslin collaborates with TopBP1 in triggering the initiation of DNA replication
Q42134579Treslin, DUE-B, and GEMC1 cannot complement Sld3 mutants in fission yeast
Q34192757USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator.
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Q29619405X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
Q27938938Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase

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