scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1017905987 |
P356 | DOI | 10.1038/NATURE05432 |
P8608 | Fatcat ID | release_hjmpqnv3qnhqncqou7etjapllm |
P3181 | OpenCitations bibliographic resource ID | 890419 |
P698 | PubMed publication ID | 17167417 |
P50 | author | John Francis Xavier Diffley | Q21165804 |
Philip Zegerman | Q57321373 | ||
P2093 | author name string | John F X Diffley | |
P2860 | cites work | Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae | Q24535011 |
CDK phosphorylation of Drc1 regulates DNA replication in fission yeast. | Q54313341 | ||
CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis | Q60482292 | ||
Preventing re-replication of chromosomal DNA. | Q24653685 | ||
mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p | Q24678671 | ||
A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle | Q27931253 | ||
A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11 | Q27931893 | ||
CLB5-dependent activation of late replication origins in S. cerevisiae. | Q27932788 | ||
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex | Q27933305 | ||
Cdc7 is required throughout the yeast S phase to activate replication origins. | Q27936667 | ||
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus | Q27937350 | ||
DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae | Q27938942 | ||
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae | Q27939221 | ||
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae | Q27939590 | ||
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication | Q27939757 | ||
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast | Q27940196 | ||
Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. | Q27940280 | ||
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response | Q28200771 | ||
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication | Q28209282 | ||
S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast | Q28216395 | ||
Interactions between BRCT repeats and phosphoproteins: tangled up in two | Q28289371 | ||
Targets of the cyclin-dependent kinase Cdk1 | Q29616479 | ||
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase | Q29618007 | ||
CLB5: a novel B cyclin from budding yeast with a role in S phase | Q29618258 | ||
Two steps in the assembly of complexes at yeast replication origins in vivo | Q29618323 | ||
An essential G1 function for cyclin-like proteins in yeast | Q29620232 | ||
Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome | Q33217275 | ||
Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. | Q33775448 | ||
Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability. | Q33958598 | ||
Regulation of early events in chromosome replication | Q34349937 | ||
The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start | Q37439494 | ||
Cell cycle regulation of DNA replication initiator factor Dbf4p | Q38324665 | ||
Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex | Q39450177 | ||
Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication | Q39576309 | ||
The Cdc7 protein kinase is required for origin firing during S phase | Q40442830 | ||
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication | Q41491045 | ||
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha. | Q42649298 | ||
Linkage of replication to start by the Cdk inhibitor Sic1. | Q51114804 | ||
P433 | issue | 7125 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
Sld2p YKL108W | Q27549320 | ||
Sld3p YGL113W | Q27550166 | ||
Protein kinase activating protein DPB11 YJL090C | Q27551215 | ||
P304 | page(s) | 281-285 | |
P577 | publication date | 2006-12-13 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast | |
P478 | volume | 445 |
Q36279546 | "The Octet": Eight Protein Kinases that Control Mammalian DNA Replication. |
Q34509265 | A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress. |
Q36248278 | A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase |
Q27680523 | A Role for USP7 in DNA Replication |
Q51462359 | A SUMO and ubiquitin code coordinates protein traffic at replication factories. |
Q42108506 | A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication. |
Q35285480 | A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint. |
Q28473344 | A dynamic stochastic model for DNA replication initiation in early embryos |
Q34134053 | A genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombe |
Q36775152 | A new MCM modification cycle regulates DNA replication initiation |
Q26829071 | A quantitative model for cyclin-dependent kinase control of the cell cycle: revisited |
Q30524859 | A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. |
Q29976893 | A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase. |
Q37301087 | A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1. |
Q33984498 | A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA |
Q24296094 | A vertebrate gene, ticrr, is an essential checkpoint and replication regulator |
Q27939055 | A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication |
Q33967609 | ATR autophosphorylation as a molecular switch for checkpoint activation. |
Q24643321 | Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation |
Q28114327 | An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation |
Q34945684 | An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence. |
Q36397627 | An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishment |
Q21203553 | An overview of Cdk1-controlled targets and processes |
Q37354105 | Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins |
Q33531604 | BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control |
Q40033702 | Beyond heterochromatin: SIR2 inhibits the initiation of DNA replication |
Q27930164 | Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. |
Q42910515 | Building up the machinery for DNA replication |
Q50335432 | CDK activity provides temporal and quantitative cues for organizing genome duplication. |
Q37589360 | CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans |
Q42114149 | CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast |
Q24622552 | CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast |
Q27932774 | CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast |
Q46856996 | CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin. |
Q29976896 | Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast |
Q27933812 | Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress |
Q35849098 | Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCFCdc4 recognition in Saccharomyces cerevisiae |
Q41305957 | Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. |
Q46252946 | Cell Cycle Synchronization in Xenopus Egg Extracts. |
Q53576726 | Cell biology: a switch for S phase. |
Q33614054 | Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction |
Q30002380 | Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation |
Q36881426 | Cell cycle regulation of DNA replication. |
Q37856411 | Cell-cycle-specific activators of the Mec1/ATR checkpoint kinase |
Q41868327 | Centrosomal localization of cyclin E-Cdk2 is required for initiation of DNA synthesis |
Q24294622 | Characterization of the interaction between the human DNA topoisomerase IIbeta-binding protein 1 (TopBP1) and the cell division cycle 45 (Cdc45) protein |
Q41792126 | Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation |
Q37076776 | Chromosome Duplication in Saccharomyces cerevisiae. |
Q36633188 | Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression |
Q50883243 | Concerted interaction between origin recognition complex (ORC), nucleosomes and replication origin DNA ensures stable ORC-origin binding. |
Q24647856 | Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing |
Q35754966 | Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase |
Q33918547 | Control of DNA replication by cyclin-dependent kinases in development |
Q64250001 | Control of Eukaryotic DNA Replication Initiation-Mechanisms to Ensure Smooth Transitions |
Q39391040 | Control of Mus81 nuclease during the cell cycle |
Q28295030 | Control of cell cycle transcription during G1 and S phases |
Q38030237 | Control over DNA replication in time and space |
Q46428907 | Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model. |
Q47117301 | Cryo-EM structure of a licensed DNA replication origin |
Q92123028 | Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle |
Q35173302 | Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation. |
Q37781559 | Cyclin-dependent kinase-dependent initiation of chromosomal DNA replication |
Q53451934 | Cyclin-dependent kinases and cell-cycle transitions: does one fit all? |
Q63384098 | DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in |
Q35176517 | DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome. |
Q36961060 | DNA polymerase epsilon: a polymerase of unusual size (and complexity). |
Q34311412 | DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast |
Q38098840 | DNA replication and homologous recombination factors: acting together to maintain genome stability |
Q38496732 | DNA replication origin activation in space and time |
Q30423333 | DNA replication: mammalian Treslin-TopBP1 interaction mirrors yeast Sld3-Dpb11 |
Q36508259 | DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9 |
Q36085679 | Damage-induced phosphorylation of Sld3 is important to block late origin firing |
Q35762655 | Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions |
Q50058814 | Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing |
Q29976889 | Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth |
Q36906226 | Dbf4: the whole is greater than the sum of its parts |
Q37663852 | Defining replication origin efficiency using DNA fiber assays |
Q27694684 | Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns |
Q35047506 | Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication |
Q39314120 | Diverse roles of Dpb2, the non-catalytic subunit of DNA polymerase ε. |
Q37687102 | DnaA, ORC, and Cdc6: similarity beyond the domains of life and diversity. |
Q24645602 | Domain architecture and biochemical characterization of vertebrate Mcm10 |
Q33607008 | Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression |
Q36999901 | Dpb11 activates the Mec1-Ddc2 complex |
Q27937150 | Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment |
Q36361925 | Dpb11 may function with RPA and DNA to initiate DNA replication |
Q35199381 | Dpb11 protein helps control assembly of the Cdc45·Mcm2-7·GINS replication fork helicase |
Q37009962 | Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development |
Q35294074 | Dynamics of DNA replication during premeiosis and early meiosis in wheat |
Q64260618 | Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model |
Q27932850 | Efficient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction |
Q35882159 | Embryonic onset of late replication requires Cdc25 down-regulation. |
Q39063003 | Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis |
Q35378055 | Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA. |
Q37956184 | Eukaryotic DNA damage checkpoint activation in response to double-strand breaks |
Q29976897 | Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. |
Q38313279 | Evolutionary conservation of the CDK targets in eukaryotic DNA replication initiation |
Q63383566 | Extra-chromosomal elements and the evolution of cellular DNA replication machineries |
Q39440326 | From structure to mechanism-understanding initiation of DNA replication. |
Q36836963 | Functional conservation of beta-hairpin DNA binding domains in the Mcm protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae. |
Q42150265 | Functional conservation of the pre-sensor one beta-finger hairpin (PS1-hp) structures in mini-chromosome maintenance proteins of Saccharomyces cerevisiae and archaea |
Q39986744 | G1 cyclin driven DNA replication. |
Q28590548 | GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication |
Q42047928 | GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication |
Q41784923 | GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding |
Q42088381 | GINS inactivation phenotypes reveal two pathways for chromatin association of replicative alpha and epsilon DNA polymerases in fission yeast |
Q42648375 | Genetic interaction of RAD53 protein kinase with histones is important for DNA replication |
Q34831943 | Genomic approaches to the initiation of DNA replication and chromatin structure reveal a complex relationship |
Q27013707 | Genomic instability in cancer |
Q30352573 | Global increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switch |
Q37340379 | Helicase activation and establishment of replication forks at chromosomal origins of replication. |
Q28289537 | Helicase loading at chromosomal origins of replication |
Q39301344 | Hog1 targets Whi5 and Msa1 transcription factors to downregulate cyclin expression upon stress. |
Q24634200 | How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? |
Q41072353 | How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication. |
Q38359785 | How the cell cycle impacts chromatin architecture and influences cell fate |
Q35629660 | Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin |
Q43902378 | Identification of a heteromeric complex that promotes DNA replication origin firing in human cells |
Q37135189 | Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation |
Q64120989 | Initiation-specific alleles of the Cdc45 helicase-activating protein |
Q37025457 | Insights into the Initiation of Eukaryotic DNA Replication |
Q36891684 | Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts |
Q36562058 | Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells |
Q36631219 | Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domain |
Q35579790 | Interplay between histone H3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage. |
Q39938475 | Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast. |
Q27009085 | Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication |
Q34998668 | MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication |
Q34825129 | MDC1 collaborates with TopBP1 in DNA replication checkpoint control |
Q40784313 | MRC1-dependent scaling of the budding yeast DNA replication timing program |
Q45955691 | MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. |
Q28475455 | Mammalian MCM loading in late-G(1) coincides with Rb hyperphosphorylation and the transition to post-transcriptional control of progression into S-phase |
Q28473912 | Mathematical modelling of DNA replication reveals a trade-off between coherence of origin activation and robustness against rereplication |
Q27679243 | Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain |
Q34203987 | Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components |
Q38288812 | Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase |
Q39144321 | Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks |
Q42571971 | Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7 |
Q28067241 | Mechanisms Governing DDK Regulation of the Initiation of DNA Replication |
Q39017132 | Mechanisms and regulation of DNA replication initiation in eukaryotes |
Q26827264 | Mechanisms for initiating cellular DNA replication |
Q34025448 | Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes |
Q93101116 | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome |
Q27666163 | Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control |
Q42773681 | Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition |
Q37689837 | Molecular mechanisms of DNA replication checkpoint activation |
Q38942428 | Multi-BRCT scaffolds use distinct strategies to support genome maintenance. |
Q35626395 | Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases |
Q41867517 | Multiple functions for Mcm2-7 ATPase motifs during replication initiation |
Q48125288 | Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis |
Q41226133 | Multiple phosphorylation of Rad9 by CDK is required for DNA damage checkpoint activation. |
Q33940725 | Multiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance. |
Q27012797 | New insights into replisome fluidity during chromosome replication |
Q64251963 | On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway |
Q42539897 | On the road to replication |
Q37075862 | Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells. |
Q51140192 | Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer. |
Q64056900 | Origin Firing Regulations to Control Genome Replication Timing |
Q38798065 | Origin plasticity during budding yeast DNA replication in vitro. |
Q42737611 | Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex |
Q37629763 | PP2ACdc55 Phosphatase Imposes Ordered Cell-Cycle Phosphorylation by Opposing Threonine Phosphorylation |
Q29976895 | Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation |
Q36725691 | Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex |
Q27935850 | Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint |
Q27656496 | Physical Interactions between Mcm10, DNA, and DNA Polymerase |
Q37040705 | Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint during G1 in Saccharomyces cerevisiae |
Q38619257 | Pre-initiation complex assembly functions as a molecular switch that splits the Mcm2-7 double hexamer |
Q60482196 | Pre-replicative complex assembly with purified proteins |
Q38798047 | Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication |
Q42086458 | Preventing DNA over-replication: a Cdk perspective |
Q35924967 | Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis. |
Q38799800 | Protein phosphatase 1 recruitment by Rif1 regulates DNA replication origin firing by counteracting DDK activity |
Q34774505 | Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation |
Q27932643 | Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination. |
Q37956282 | Quality control in the initiation of eukaryotic DNA replication |
Q35904350 | Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machinery |
Q30823962 | RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans |
Q47164948 | RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin |
Q28541436 | Rad4 mainly functions in Chk1-mediated DNA damage checkpoint pathway as a scaffold protein in the fission yeast Schizosaccharomyces pombe |
Q37546864 | Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1. |
Q36185258 | RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts |
Q37739460 | RecQ4: the second replicative helicase? |
Q30361445 | RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells |
Q35010078 | Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells |
Q41960725 | Regulated eukaryotic DNA replication origin firing with purified proteins |
Q38120365 | Regulating DNA replication in eukarya |
Q37777343 | Regulation of DNA replication by chromatin structures: accessibility and recruitment. |
Q35655603 | Regulation of DNA replication during development |
Q50423784 | Regulation of Replication Origins. |
Q38032248 | Regulation of the cell division cycle in Trypanosoma brucei |
Q37777965 | Regulation of the initiation step of DNA replication by cyclin-dependent kinases. |
Q53341848 | Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC. |
Q35191354 | Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. |
Q42929219 | Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels. |
Q37993652 | Replication fork dynamics and the DNA damage response. |
Q36875519 | Replication in context: dynamic regulation of DNA replication patterns in metazoans |
Q37169815 | Replication initiation complex formation in the absence of nuclear function in Xenopus. |
Q34547673 | Replication licensing and the DNA damage checkpoint. |
Q37805335 | Replication origins and timing of temporal replication in budding yeast: how to solve the conundrum? |
Q27937207 | Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex |
Q54110968 | Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition. |
Q37724141 | Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities. |
Q52709084 | Roles of SUMO in Replication Initiation, Progression, and Termination. |
Q90099427 | SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation |
Q28477442 | Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε |
Q36642991 | Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis. |
Q27930177 | Sld2 binds to origin single-stranded DNA and stimulates DNA annealing |
Q36067242 | Sld3-MCM Interaction Facilitated by Dbf4-Dependent Kinase Defines an Essential Step in Eukaryotic DNA Replication Initiation |
Q27933558 | Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast |
Q38831197 | Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast. |
Q27661763 | Solution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM Motif |
Q26766086 | Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding |
Q24657362 | Structural basis for DNA binding by replication initiator Mcm10 |
Q40970716 | Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1. |
Q38037370 | Structural biology of replication initiation factor Mcm10. |
Q36315605 | Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae |
Q38081728 | Structure and evolutionary origins of the CMG complex |
Q37673223 | Structure and function of the GINS complex, a key component of the eukaryotic replisome |
Q59801443 | Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome |
Q36919769 | Structure of human Cdc45 and implications for CMG helicase function |
Q38259475 | Switch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated |
Q42105504 | TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. |
Q42322670 | Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection |
Q30485446 | Tetrapyrrole signal as a cell-cycle coordinator from organelle to nuclear DNA replication in plant cells. |
Q37065907 | The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation |
Q47102294 | The CDK-PLK1 axis targets the DNA damage checkpoint sensor protein RAD9 to promote cell proliferation and tolerance to genotoxic stress |
Q35213348 | The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex. |
Q64246789 | The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7 |
Q33704991 | The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation |
Q29976890 | The Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly |
Q33586599 | The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 |
Q37451513 | The Mcm complex: unwinding the mechanism of a replicative helicase. |
Q26861045 | The Mcm2-7 replicative helicase: a promising chemotherapeutic target |
Q50198142 | The Mcm2-7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing |
Q35787401 | The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase |
Q27932783 | The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis |
Q96769248 | The Role of Rif1 in telomere length regulation is separable from its role in origin firing |
Q33944167 | The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis |
Q90482890 | The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast |
Q33300908 | The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. |
Q37169802 | The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication |
Q34489800 | The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding |
Q27932666 | The replication initiation protein Sld2 regulates helicase assembly |
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