The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast

scientific article published on 04 October 2019

The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1008430
P932PMC publication ID6795477
P698PubMed publication ID31584938

P50authorElizabeth KwanQ57324635
Bonita J BrewerQ90482882
M K RaghuramanQ90482886
P2093author name stringGina M Alvino
Kelsey L Lynch
P2860cites workSld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeQ24535011
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The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication forkQ27929525
Histone acetylation regulates the time of replication origin firingQ27930649
A group of interacting yeast DNA replication genesQ27932669
CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeastQ27932774
CLB5-dependent activation of late replication origins in S. cerevisiae.Q27932788
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Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.Q27935340
Ribosome synthesis in Saccharomyces cerevisiaeQ27935371
Cdc7 is required throughout the yeast S phase to activate replication origins.Q27936667
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Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiaeQ27938701
The Elg1 replication factor C-like complex functions in PCNA unloading during DNA replication.Q27939562
Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitmentQ27940145
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Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolutionQ28658367
Two steps in the assembly of complexes at yeast replication origins in vivoQ29618323
Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activationQ29976895
Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locusQ30479469
Titration of four replication factors is essential for the Xenopus laevis midblastula transitionQ30566253
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Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae.Q33347123
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4Q33586599
Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progressionQ33607008
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Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replicationQ34480880
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespanQ34625412
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Abnormality in initiation program of DNA replication is monitored by the highly repetitive rRNA gene array on chromosome XII in budding yeastQ35642142
Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formationQ35746771
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The level of origin firing inversely affects the rate of replication fork progression.Q36804052
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Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.Q37076181
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rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.Q37242035
Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stabilityQ37472978
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An auxin-based degron system for the rapid depletion of proteins in nonplant cells.Q39774277
Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast.Q39938475
The Cdc7 protein kinase is required for origin firing during S phaseQ40442830
Replication in hydroxyurea: it's a matter of timeQ40816185
Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylationQ41792126
A replication fork barrier at the 3' end of yeast ribosomal RNA genesQ42002385
The dynamics of genome replication using deep sequencing.Q42090523
Nucleosomes influence multiple steps during replication initiationQ42290808
DNA replication stress restricts ribosomal DNA copy number.Q42365210
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.Q42631705
Genomic architecture and inheritance of human ribosomal RNA gene clustersQ42809653
Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.Q43178320
Origin association of Sld3, Sld7, and Cdc45 proteins is a key step for determination of origin-firing timingQ43415186
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.Q44079733
Mapping of early firing origins on a replication profile of budding yeastQ44093911
A yeast origin of replication is activated late in S phaseQ44228986
A central role for DNA replication forks in checkpoint activation and responseQ44455872
The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypesQ46315295
Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast.Q47136088
Late DNA synthesis in heterochromatinQ47875224
Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timingQ50058814
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P304page(s)e1008430
P577publication date2019-10-04
P1433published inPLOS GeneticsQ1893441
P1476titleThe effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast
P478volume15

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Q100558661Evolution of DNA replication origin specification and gene silencing mechanismscites workP2860

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