Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo.

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Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...876340C
P356DOI10.1371/JOURNAL.PONE.0076340
P932PMC publication ID3794942
P698PubMed publication ID24130769
P5875ResearchGate publication ID257839939

P50authorPinpin LinQ63656287
P2093author name stringWei-Jan Huang
Ying-Jan Wang
Yi-Ching Wang
Yi-An Chen
Yi-Shiou Chiou
Hui-Wen Chiu
Sheng-Yow Ho
Ya-Ling Yeh
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Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagyQ34339721
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DNA damage and autophagyQ35017721
Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancerQ35758280
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viabilityQ35916071
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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1Q36017473
Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenograftsQ36085732
A phase II trial of vorinostat (suberoylanilide hydroxamic acid) in metastatic breast cancer: a California Cancer Consortium studyQ36528653
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Comet sensitivity in assessing DNA damage and repair in different cell cycle stages.Q53341657
In vitro and in vivo radiation resistance associated with CD3 surface antigen expression in T-lineage acute lymphoblastic leukemiaQ54283308
Eeyarestatin causes cervical cancer cell sensitization to bortezomib treatment by augmenting ER stress and CHOP expressionQ85306996
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Inhibition of histone deacetylation: a strategy for tumor radiosensitizationQ36935075
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New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagyQ37981834
Acetylation: a novel link between double-strand break repair and autophagyQ37994172
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Vorinostat for treatment of cutaneous manifestations of advanced primary cutaneous T-cell lymphomaQ39336768
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Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinomaQ39641710
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Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibitionQ39677848
Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosisQ39732599
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaksQ39793584
ATM blocks tunicamycin-induced endoplasmic reticulum stressQ39870208
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Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathwaysQ39880012
Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagyQ39943635
Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell deathQ40022622
Resveratrol inhibits heregulin-beta1-mediated matrix metalloproteinase-9 expression and cell invasion in human breast cancer cells.Q40102871
Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of gamma-H2AX fociQ40240295
HDACs link the DNA damage response, processing of double-strand breaks and autophagyQ41979339
Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancerQ42492006
The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypesQ42511189
HDAC6 expression is correlated with better survival in breast cancer.Q45122014
3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.Q46839472
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectlung metastasisQ1877473
P304page(s)e76340
P577publication date2013-10-10
P1433published inPLOS OneQ564954
P1476titleSuberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo
P478volume8

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