Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex

scientific article

Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/CDG217
P932PMC publication ID156089
P698PubMed publication ID12727875
P5875ResearchGate publication ID10776962

P50authorMy Hang V. HuynhQ6945612
Vern CarruthersQ42718560
L. David SibleyQ63241949
P2093author name stringWandy L Beatty
Jill M Harper
Karen E Rabenau
P2860cites workRole of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasionQ28210733
TRAP is necessary for gliding motility and infectivity of plasmodium sporozoitesQ30044862
Time-lapse video microscopy of gliding motility in Toxoplasma gondii reveals a novel, biphasic mechanism of cell locomotionQ30483977
The toxoplasma micronemal protein MIC4 is an adhesin composed of six conserved apple domainsQ31506583
The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels.Q31592876
Toxoplasma gondii uses sulfated proteoglycans for substrate and host cell attachmentQ33596699
Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cellsQ34005337
Lytic cycle of Toxoplasma gondiiQ34023676
Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii.Q34375972
Host cell invasion by the opportunistic pathogen Toxoplasma gondiiQ34500617
'The glideosome': a dynamic complex powering gliding motion and host cell invasion by Toxoplasma gondii.Q34760540
Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systemsQ34970141
Attachment of Toxoplasma gondii to host cells is host cell cycle dependentQ35523545
Toxoplasmic encephalitis in AIDS.Q35810946
Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasitesQ36316326
Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoringQ36375654
Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.Q36721098
Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore.Q37404567
Safe haven: the cell biology of nonfusogenic pathogen vacuoles.Q37883692
The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteasesQ38312554
The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesinQ39647289
The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin that binds to both the surface of the host cells and the surface of the parasiteQ40826489
Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondiiQ40831221
A Toxoplasma lectin-like activity specific for sulfated polysaccharides is involved in host cell infectionQ40982669
Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasiteQ41214560
Toxoplasma gondii: the role of parasite surface and secreted proteins in host cell invasionQ41232533
Toxoplasma gondii: the role of a 30-kDa surface protein in host cell invasion.Q41641057
Ethanol and acetaldehyde elevate intracellular [Ca2+] and stimulate microneme discharge in Toxoplasma gondiiQ41814456
Toxoplasma gondii micronemal protein MIC1 is a lactose-binding lectin.Q43669512
Molecular characterization of a thrombospondin-related anonymous protein homologue in Neospora caninumQ47877546
Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2.Q48054253
The MIC1 microneme protein of Toxoplasma gondii contains a duplicated receptor-like domain and binds to host cell surfaceQ48056588
A family of transmembrane microneme proteins of Toxoplasma gondii contain EGF-like domains and function as escorters.Q48316905
Toxoplasma gondii: molecular cloning and characterization of a novel 18-kDa secretory antigen, TgMIC10.Q48372755
Targeted disruption of the glycosylphosphatidylinositol-anchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice.Q52540316
Invasion of Toxoplasma gondii occurs by active penetration of the host cell.Q53847562
Gene knock-outs and allelic replacements in Toxoplasma gondii: HXGPRT as a selectable marker for hit-and-run mutagenesisQ59178755
TgM2AP participates in Toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2Q63409182
Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondiiQ63409196
Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblastsQ73478363
Secretion of micronemal proteins is associated with toxoplasma invasion of host cellsQ73510453
Congenital toxoplasmosisQ74526658
C-terminal processing of the toxoplasma protein MIC2 is essential for invasion into host cellsQ78625792
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)2082-2090
P577publication date2003-05-01
P1433published inThe EMBO JournalQ1278554
P1476titleRapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex
P478volume22

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