A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii

scientific article published on April 2008

A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BC20070076
P8608Fatcat IDrelease_zjrglfch6fg5ljelop7xifxysa
P932PMC publication ID2663041
P698PubMed publication ID17995454

P50authorVern CarruthersQ42718560
P2093author name stringIsabelle Coppens
Susannah D Brydges
Jill M Harper
Fabiola Parussini
P2860cites workToxoplasma MIC2 is a major determinant of invasion and virulenceQ27320169
Binding of the Golgi sorting receptor muclin to pancreatic zymogens through sulfated O-linked oligosaccharidesQ28591204
Processing and targeting of granule proteins in human neutrophilsQ28611911
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ERQ29615171
Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathwayQ29620187
Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparumQ30041439
Molecular characterization of TgMIC5, a proteolytically processed antigen secreted from the micronemes of Toxoplasma gondiiQ30967151
A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual charge asymmetry.Q33207269
Toxoplasma gondii: conserved protein machinery in an unusual secretory pathway?Q33878626
Mix and match modules: structure and function of microneme proteins in apicomplexan parasites.Q34167780
Molecular characterization of a 23-kilodalton major antigen secreted by Toxoplasma gondiiQ34308254
Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii.Q34375972
A plastid of probable green algal origin in Apicomplexan parasites.Q34738267
Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complexQ35019075
A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complexQ35128202
The protozoan parasite Toxoplasma gondii targets proteins to dense granules and the vacuolar space using both conserved and unusual mechanismsQ36255436
Toxoplasma gondii expressed sequence tags: insight into tachyzoite gene expressionQ36841712
Recycling of Raft-associated prohormone sorting receptor carboxypeptidase E requires interaction with ARF6.Q37155177
Biogenesis of secretory granules. Implications arising from the immature secretory granule in the regulated pathway of secretionQ37345058
Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondiiQ39455769
Constitutive and regulated secretion of proteinsQ39683816
Expression of pro-Muclin in pancreatic AR42J cells induces functional regulated secretory granulesQ40403521
The C-terminus of prohormone convertase 2 is sufficient and necessary for Raft association and sorting to the regulated secretory pathwayQ40545679
An alternate targeting pathway for procathepsin L in mouse fibroblastsQ40740821
Targeted deletion of MIC5 enhances trimming proteolysis of Toxoplasma invasion proteinsQ40929404
Host cell invasion by Toxoplasma gondiiQ41712109
PEPSINOGEN B: THE ZYMOGEN OF PEPSIN BQ42191991
Toxoplasma gondii ADP-ribosylation factor 1 mediates enhanced release of constitutively secreted dense granule proteinsQ43559405
Characterization of a family of rhoptry proteins of Toxoplasma gondiiQ43935447
Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2.Q48054253
Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptideQ50336430
Golgi biogenesis in Toxoplasma gondiiQ59098607
Constitutive Calcium-independent Release ofToxoplasma gondiiDense Granules Occurs through the NSF/SNAP/SNARE/Rab MachineryQ59178752
TgM2AP participates in Toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2Q63409182
Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondiiQ63409196
Modification of tryptophan residues in trypsin, α-chymotrypsin and pepsinogenQ71193512
Differential membrane targeting of the secretory proteins GRA4 and GRA6 within the parasitophorous vacuole formed by Toxoplasma gondiiQ73022377
The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptorsQ73444643
Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblastsQ73478363
Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanismsQ73949950
The pro region of Toxoplasma ROP1 is a rhoptry-targeting signalQ74402776
Processing of Toxoplasma ROP1 protein in nascent rhoptriesQ77676237
P433issue4
P921main subjectToxoplasma gondiiQ131003
P1104number of pages12
P304page(s)253-264
P577publication date2008-04-01
P1433published inBiology of the CellQ1254604
P1476titleA transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii
P478volume100

Reverse relations

cites work (P2860)
Q37501232A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection
Q30573321A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii
Q64913718Calcium negatively regulates secretion from dense granules in Toxoplasma gondii.
Q34016345Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii
Q37635978Cathepsin proteases in Toxoplasma gondii
Q34788697Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression
Q35046321Forward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acids
Q37446287Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins
Q50045452Intersection of Endocytic and Exocytic Systems in Toxoplasma gondii.
Q39756124Molecular signals in the trafficking of Toxoplasma gondii protein MIC3 to the micronemes
Q30044113Motility precedes egress of malaria parasites from oocysts
Q36579600Non-canonical maturation of two papain-family proteases in Toxoplasma gondii
Q55236860Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite.
Q35034166Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion
Q37684373Rhoptry protein 5 (ROP5) Is a Key Virulence Factor in Neospora caninum
Q27656389Toxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl
Q36869985Toxoplasma gondii Tic20 is essential for apicoplast protein import
Q34316176Toxoplasma gondii transmembrane microneme proteins and their modular design
Q36796400Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

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