Rhoptry protein 5 (ROP5) Is a Key Virulence Factor in Neospora caninum

scientific article published on 07 March 2017

Rhoptry protein 5 (ROP5) Is a Key Virulence Factor in Neospora caninum is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMICB.2017.00370
P932PMC publication ID5340095
P698PubMed publication ID28326073

P2093author name stringLei Ma
Jing Liu
Xiao Zhang
Qun Liu
Yong Fu
Muzi Li
P2860cites workRecent expansion of Toxoplasma through enhanced oral transmissionQ47411368
Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.Q47868849
GRA 14, a novel dense granule protein from Neospora caninum.Q50949113
The Neospora caninum-Spain 7 isolate induces placental damage, fetal death and abortion in cattle when inoculated in early gestationQ84202625
Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategyQ21090491
Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite InterfaceQ27316912
A nuclear factor of high mobility group box protein in Toxoplasma gondiiQ27331688
The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18Q27341809
A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma VirulenceQ27670588
Neospora caninum Activates p38 MAPK as an Evasion Mechanism against Innate ImmunityQ28830507
Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries.Q30328708
Epidemiology and control of neosporosis and Neospora caninumQ31109044
Apical membrane antigen 1 is a cross-reactive antigen between Neospora caninum and Toxoplasma gondii, and the anti-NcAMA1 antibody inhibits host cell invasion by both parasitesQ33265989
ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondiiQ33274196
A unique dual activity amino acid hydroxylase in Toxoplasma gondiiQ33416807
A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.Q33591077
The construction and use of log-odds substitution scores for multiple sequence alignmentQ33640089
Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9.Q33648073
Recent advances in Neospora and neosporosisQ33717106
ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninumQ33753887
The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in miceQ33861156
Influence of Neospora caninum intra-specific variability in the outcome of infection in a pregnant BALB/c mouse modelQ33883788
Tumor proteomics by multivariate analysis on individual pathway data for characterization of vulvar cancer phenotypesQ34231541
Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genesQ34339536
A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondiiQ34591236
Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.Q34757058
Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinasesQ35034984
Forward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acidsQ35046321
A Toxoplasma gondii mutant highlights the importance of translational regulation in the apicoplast during animal infectionQ35142236
Neospora caninum Recruits Host Cell Structures to Its Parasitophorous Vacuole and Salvages Lipids from OrganellesQ35573325
Toxoplasma as a novel system for motility.Q35705362
Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondiiQ35751387
Two Essential Light Chains Regulate the MyoA Lever Arm To Promote Toxoplasma Gliding MotilityQ36143585
Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infectionsQ36212957
The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membraneQ36377984
The Apoptotic Role of Metacaspase in Toxoplasma gondiiQ36475303
The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation.Q36565374
ApiAP2 transcription factor restricts development of the Toxoplasma tissue cystQ36799076
Polymorphic secreted kinases are key virulence factors in toxoplasmosisQ37105671
A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondiiQ37144745
Toxoplasma transcription factor TgAP2XI-5 regulates the expression of genes involved in parasite virulence and host invasion.Q37312183
The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.Q37334013
COX-2 Inhibition Reduces Brucella Bacterial Burden in Draining Lymph Nodes.Q37492107
Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouseQ37519590
Update on the Diagnosis and Management of Neospora caninum Infections in DogsQ37799444
Virulence factors of Toxoplasma gondiiQ38046033
The ROP18 and ROP5 gene allele types are highly predictive of virulence in mice across globally distributed strains of Toxoplasma gondiiQ38928515
Transcriptional Profiling of Type II Toxin-Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967-HP0968 SystemQ39128063
Stage-specific proteome signatures in early bovine embryo developmentQ39147521
Toxoplasma gondii sporozoites form a transient parasitophorous vacuole that is impermeable and contains only a subset of dense-granule proteinsQ39831424
A new microneme protein of Neospora caninum, NcMIC8 is involved in host cell invasionQ40361394
Characterization of the Neospora caninum NcROP40 and NcROP2Fam-1 rhoptry proteins during the tachyzoite lytic cycle.Q40369803
Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondiiQ40501292
Cell mediated immune responses in the placenta following challenge of vaccinated pregnant heifers with Neospora caninum.Q40916195
Dose-dependent effects of experimental infection with the virulent Neospora caninum Nc-Spain7 isolate in a pregnant mouse modelQ41143239
Detection of Neospora caninum-DNA in feces collected from dogs in Shenyang (China) and ITS1 phylogenetic analysisQ43523392
Neospora abortions in dairy cattle: diagnosis, mode of transmission and controlQ43577383
Reduced cerebral infection of Neospora caninum in BALB/c mice vaccinated with recombinant Brucella abortus RB51 strains expressing N. caninum SRS2 and GRA7 proteinsQ43713735
Pathogenic characterization in mice of Neospora caninum isolates obtained from asymptomatic calvesQ44460553
First isolation of Neospora caninum from blood of a naturally infected adult dairy cow in Beijing, China.Q45941708
P921main subjectNeospora caninumQ1431408
P304page(s)370
P577publication date2017-03-07
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleRhoptry protein 5 (ROP5) Is a Key Virulence Factor in Neospora caninum
P478volume8

Reverse relations

cites work (P2860)
Q58702723Genome Wide Identification of Mutational Hotspots in the Apicomplexan Parasite Neospora caninum and the Implications for Virulence
Q90020504NcGRA17 is an important regulator of parasitophorous vacuole morphology and pathogenicity of Neospora caninum
Q90101472Neospora caninum Dense Granule Protein 7 Regulates the Pathogenesis of Neosporosis by Modulating Host Immune Response
Q99562778Proteomic Characterization of Host-Pathogen Interactions during Bovine Trophoblast Cell Line Infection by Neospora caninum

Search more.