scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1470-2045(02)00931-2 |
P698 | PubMed publication ID | 12473516 |
P50 | author | Carlo Maria Croce | Q640381 |
P2093 | author name string | Kay Huebner | |
Nicola Zanesi | |||
Alexey Palamarchuk | |||
Yuri Pekarsky | |||
P2860 | cites work | Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer | Q41332396 |
Origin of genes encoding multi-enzymatic proteins in eukaryotes. | Q41549764 | ||
Molecular follow-up of preneoplastic lesions in bronchial epithelium of former Chernobyl clean-up workers | Q43955974 | ||
The FHIT gene 3p14.2 is abnormal in lung cancer | Q53455201 | ||
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis | Q58072287 | ||
Tumor suppressor genes | Q68264184 | ||
Role of chromosome translocations in human neoplasia | Q68818574 | ||
Involvement of the bcl-2 gene in human follicular lymphoma | Q69870224 | ||
Translocation t(3;8)(p14.2;q24.1) in renal cell carcinoma affects expression of the common fragile site at 3p14(FRA3B) in lymphocytes | Q70378721 | ||
Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma | Q70449918 | ||
Clonal genetic alterations in the lungs of current and former smokers | Q73443322 | ||
The expression of Fhit protein is related inversely to disease progression in patients with breast carcinoma | Q73549634 | ||
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction | Q74306391 | ||
The tumor suppressor protein Fhit. A novel interaction with tubulin | Q78122448 | ||
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit | Q24313542 | ||
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans | Q24317206 | ||
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase | Q24320228 | ||
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers | Q24321912 | ||
The tumor spectrum in FHIT-deficient mice | Q24555215 | ||
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit | Q24595534 | ||
Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene | Q24644705 | ||
Muir-Torre-like syndrome in Fhit-deficient mice | Q24676755 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Replacement of Fhit in cancer cells suppresses tumorigenicity | Q33726007 | ||
The histidine triad superfamily of nucleotide-binding proteins | Q33738439 | ||
Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability | Q33963998 | ||
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines | Q34019362 | ||
Potential cancer therapy with the fragile histidine triad gene: review of the preclinical studies | Q34442403 | ||
FHIT gene therapy prevents tumor development in Fhit-deficient mice. | Q34729169 | ||
The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control | Q35552007 | ||
Cancer-specific chromosome alterations in the constitutive fragile region FRA3B. | Q36396981 | ||
The use of epidemiology, scientific data, and regulatory authority to determine risk factors in cancer of some organs of the digestive system. 2. Esophageal cancer | Q36489743 | ||
Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features | Q36621318 | ||
Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion | Q36827321 | ||
Chromosome aberrations and cancer | Q37538405 | ||
Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites | Q37559058 | ||
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas | Q40843340 | ||
P433 | issue | 12 | |
P921 | main subject | prevention | Q1717246 |
gene discovery | Q129262352 | ||
P1104 | number of pages | 7 | |
P304 | page(s) | 748-754 | |
P577 | publication date | 2002-12-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Lancet Oncology Commission | Q13747613 |
P1476 | title | FHIT: from gene discovery to cancer treatment and prevention | |
P478 | volume | 3 |
Q44683356 | 5'-CpG island methylation of the FHIT gene is associated with reduced protein expression and higher clinical stage in cervical carcinomas |
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Q30670527 | Association of activated Gαq to the tumor suppressor Fhit is enhanced by phospholipase Cβ |
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Q45103584 | Contig array CGH at 3p14.2 points to the FRA3B/FHIT common fragile region as the target gene in diffuse large B-cell lymphoma. |
Q46497555 | Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome |
Q28252440 | Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer |
Q40368333 | Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR. |
Q35147070 | Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements |
Q43275576 | FHIT gene sequence variants and reduced Fhit protein expression in glioblastoma multiforme |
Q44827323 | FHIT mRNA and protein expression in hepatocellular carcinoma |
Q46235892 | FHIT promoter DNA methylation and expression analysis in childhood acute lymphoblastic leukemia |
Q35191084 | FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells |
Q40274111 | Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines |
Q39771185 | Fhit regulates invasion of lung tumor cells |
Q37352008 | Fhit tumor suppressor: guardian of the preneoplastic genome |
Q33761959 | Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells |
Q46733687 | Frequent epigenetic silencing of the FHIT gene in penile squamous cell carcinomas |
Q35877178 | Gallbladder cancer: lessons from a rare tumour |
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Q37948622 | HPV, KRAS mutations, alcohol consumption and tobacco smoking effects on esophageal squamous-cell carcinoma carcinogenesis. |
Q57261261 | High resolution analysis of follicular lymphoma genomes reveals somatic recurrent sites of copy-neutral loss of heterozygosity and copy number alterations that target single genes |
Q83820573 | High throughput tissue microarray analysis of FHIT expression in diffuse large cell B-cell lymphoma from Saudi Arabia |
Q42258973 | Human papillomavirus and non-small cell lung cancer |
Q34444611 | Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer |
Q34118625 | Identification of putative cancer genes through data integration and comparative genomics between plants and humans. |
Q37272413 | Identification of the HIT-45 protein from Trypanosoma brucei as an FHIT protein/dinucleoside triphosphatase: substrate specificity studies on the recombinant and endogenous proteins |
Q34650922 | Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine |
Q46489933 | Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma |
Q48117196 | Lack of association of fragile histidine triad (FHIT) polymorphisms with lung cancer in the Korean population |
Q34382463 | Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection |
Q44623571 | Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer. |
Q33866516 | Loss of fragile histidine triad protein expression in inflammatory bowel disease |
Q36655128 | Methylation in esophageal carcinogenesis |
Q37313424 | Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy |
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Q37354050 | Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma |
Q35563102 | Search for unknown tumor‐antagonizing genes |
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Q40339478 | Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia |
Q36610527 | The expression of FHIT, PCNA and EGFR in benign and malignant breast lesions |
Q36299944 | The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity. |
Q35112786 | Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis |
Q92920001 | Translatable gene therapy for lung cancer using Crispr CAS9-an exploratory review |
Q97532078 | Upregulation of FHIT gene expression in endometrial carcinoma by RNA activation |
Q21283974 | Widespread presence of "bacterial-like" PPP phosphatases in eukaryotes |
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