| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Julien JP | |
| Mushynski WE | |||
| Nguyen MD | |||
| P2860 | cites work | Neurofilaments in health and disease | Q64869492 |
| Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus | Q71058491 | ||
| Cyclin-dependent kinase-5 is associated with lipofuscin in motor neurones in amyotrophic lateral sclerosis | Q74576356 | ||
| Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor | Q24292411 | ||
| Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems | Q24311132 | ||
| An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator | Q24315951 | ||
| p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 | Q24320432 | ||
| Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain | Q24597567 | ||
| Structure and regulation of the CDK5-p25(nck5a) complex | Q27635171 | ||
| A novel cdc2-related protein kinase expressed in the nervous system | Q28116104 | ||
| Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration | Q28140796 | ||
| Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase | Q28141045 | ||
| NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein | Q28143527 | ||
| Neurotoxicity induces cleavage of p35 to p25 by calpain | Q28145382 | ||
| Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology | Q28199047 | ||
| Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin | Q28202607 | ||
| Role of the reelin signaling pathway in central nervous system development | Q28214353 | ||
| Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29 | Q28215152 | ||
| Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality | Q28302232 | ||
| The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic | Q28366369 | ||
| Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm | Q28507460 | ||
| Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling | Q28510174 | ||
| Callosal axon guidance defects in p35(-/-) mice | Q28511856 | ||
| Cyclin-dependent kinase 5 is required for associative learning | Q28511889 | ||
| Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1 | Q28565028 | ||
| Regulation of NMDA receptors by cyclin-dependent kinase-5 | Q28567371 | ||
| Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death | Q28587075 | ||
| p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment | Q28589437 | ||
| Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions | Q28591963 | ||
| Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth | Q28594587 | ||
| Cyclin-dependent kinases: engines, clocks, and microprocessors | Q29614786 | ||
| Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin | Q30477577 | ||
| Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro | Q30884130 | ||
| E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. | Q33180163 | ||
| Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors | Q33604662 | ||
| The Sp-family of transcription factors | Q33778355 | ||
| Cell cycle control | Q33918236 | ||
| The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning | Q48049227 | ||
| Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death | Q48087625 | ||
| RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis. | Q48258122 | ||
| Alterations in cyclin-dependent protein kinase 5 (CDK5) protein levels, activity and immunocytochemistry in canine motor neuron disease | Q48344634 | ||
| p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway | Q48401217 | ||
| Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice | Q48639403 | ||
| Changes in the expression of novel Cdk5 activator messenger RNA (p39nck5ai mRNA) during rat brain development | Q48647484 | ||
| p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease | Q48651496 | ||
| Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain | Q48706959 | ||
| Regulation of neuronal survival and death by E2F-dependent gene repression and derepression | Q48711885 | ||
| Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse | Q48712690 | ||
| Region-specific expression of cell cycle inhibitors in the adult brain | Q48783693 | ||
| Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice | Q49065674 | ||
| Neuronal cyclin-dependent kinase 5 activity is critical for survival. | Q49070859 | ||
| Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases | Q49140750 | ||
| Neuronal CDK7 in hippocampus is related to aging and Alzheimer disease | Q49140780 | ||
| Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment. | Q49140845 | ||
| Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II. | Q53322724 | ||
| The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity | Q59097192 | ||
| Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors | Q33944246 | ||
| Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases | Q33968957 | ||
| A decade of CDK5. | Q34093501 | ||
| The neurobiology of slow synaptic transmission | Q34100272 | ||
| LIS1. let's interact sometimes... (part 1). | Q34132930 | ||
| Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases | Q34142252 | ||
| Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded | Q34175381 | ||
| Neuronal apoptosis at the G1/S cell cycle checkpoint | Q34361816 | ||
| Innate immunity: the missing link in neuroprotection and neurodegeneration? | Q34627260 | ||
| Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5 | Q35084361 | ||
| Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation | Q35640910 | ||
| The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease | Q35829694 | ||
| Role of cyclins in neuronal differentiation of immortalized hippocampal cells | Q36573600 | ||
| A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. | Q36828945 | ||
| Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism | Q36850138 | ||
| Altered distribution of cell cycle transcriptional regulators during Alzheimer disease. | Q36931808 | ||
| Cell cycle regulation of a Xenopus Wee1-like kinase | Q37378230 | ||
| Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors | Q37378505 | ||
| Cyclin-dependent kinases as a therapeutic target for stroke. | Q37445826 | ||
| The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. | Q37647121 | ||
| GC box-binding transcription factors control the neuronal specific transcription of the cyclin-dependent kinase 5 regulator p35. | Q38294385 | ||
| Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3. | Q39646468 | ||
| p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases | Q40022880 | ||
| Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection | Q40746413 | ||
| Transcriptional regulation of cortical neuron migration by POU domain factors | Q40748974 | ||
| Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis | Q40999741 | ||
| Regulation of expression and activity of distinct pRB, E2F, D-type cyclin, and CKI family members during terminal differentiation of P19 cells | Q41003091 | ||
| DNA replication precedes neuronal cell death in Alzheimer's disease. | Q42502934 | ||
| Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease | Q42508999 | ||
| Neuroscience. A kinase to dampen the effects of cocaine? | Q43577048 | ||
| ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1. | Q43594596 | ||
| Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo. | Q43697238 | ||
| Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway | Q43783336 | ||
| Neocortical cell migration: GABAergic neurons and cells in layers I and VI move in a cyclin-dependent kinase 5-independent manner. | Q43819972 | ||
| Pituitary adenylate cyclase activating polypeptide anti-mitogenic signaling in cerebral cortical progenitors is regulated by p57Kip2-dependent CDK2 activity. | Q43906964 | ||
| Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity. | Q43940169 | ||
| Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis | Q44149270 | ||
| The cdc25 protein contains an intrinsic phosphatase activity | Q46716281 | ||
| Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. | Q46903641 | ||
| Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration | Q47836277 | ||
| Structural principles in cell-cycle control: beyond the CDKs | Q47948900 | ||
| A novel disruption of cortical development in p35(-/-) mice distinct from reeler | Q47996554 | ||
| Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system | Q48038238 | ||
| P433 | issue | 12 | |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 1294-1306 | |
| P577 | publication date | 2002-12-01 | |
| P1433 | published in | Cell Death & Differentiation | Q2943974 |
| P1476 | title | Cycling at the interface between neurodevelopment and neurodegeneration | |
| P478 | volume | 9 |
| Q34232193 | A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation |
| Q37053631 | An unusual member of the Cdk family: Cdk5. |
| Q35935017 | Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury |
| Q37693739 | Bridging the Divide between Neuroprosthetic Design, Tissue Engineering and Neurobiology |
| Q37323185 | Cdk5 and the non-catalytic arrest of the neuronal cell cycle |
| Q24299163 | Cdk5: multitasking between physiological and pathological conditions |
| Q35006482 | Cell cycle activation and spinal cord injury |
| Q37883217 | Cell cycle deregulation in the neurons of Alzheimer's disease |
| Q44376552 | Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. |
| Q45213406 | Cell injury and premature neurodegeneration in focal malformations of cortical development |
| Q36057674 | Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress |
| Q82029146 | Chapter 6 Animal models of motor neuron death |
| Q40046989 | Chemotactic and mitogenic stimuli of neuronal apoptosis in patients with medically intractable temporal lobe epilepsy |
| Q46486132 | Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. |
| Q35023914 | Development and death of neurons: sealed by a common fate? |
| Q46202882 | Dopamine induces supernumerary centrosomes and subsequent cell death through Cdk2 up-regulation in dopaminergic neuronal cells |
| Q36349640 | Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein |
| Q41904593 | ERK MAP kinase activation in spinal cord regulates phosphorylation of Cdk5 at serine 159 and contributes to peripheral inflammation induced pain/hypersensitivity |
| Q40117479 | Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signalling. |
| Q40517469 | Expression of gp100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region |
| Q34422582 | Genetic determinants at the interface of cancer and neurodegenerative disease |
| Q40016960 | HIV-1 Tat inhibits NGF-induced Egr-1 transcriptional activity and consequent p35 expression in neural cells |
| Q36411543 | Immunological findings in autism |
| Q28483833 | Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A |
| Q34441821 | Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats |
| Q46557913 | Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons |
| Q36604805 | Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors |
| Q44973766 | Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations |
| Q31122876 | Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress |
| Q48008609 | Lentiviral Vector-Mediated p27kip1 Expression Facilitates Recovery After Spinal Cord Injury |
| Q53114756 | MCM7 expression is altered in rat after spinal cord injury. |
| Q36938909 | Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing. |
| Q45325636 | MiRNA-124 is a link between measles virus persistent infection and cell division of human neuroblastoma cells. |
| Q37069478 | MicroRNAs (miRNAs) in neurodegenerative diseases |
| Q39779374 | Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. |
| Q34737339 | Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration |
| Q33831087 | Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells |
| Q36627277 | Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling. |
| Q28191537 | PEDF: a multifaceted neurotrophic factor |
| Q37948585 | Parkinson's disease and cancer: two wars, one front |
| Q48806423 | Phospho-Rb mediating cell cycle reentry induces early apoptosis following oxygen-glucose deprivation in rat cortical neurons |
| Q31147426 | Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor |
| Q48181931 | Phosphorylated retinoblastoma protein (p-Rb) is involved in neuronal apoptosis after traumatic brain injury in adult rats |
| Q38942093 | Progranulin Deficiency Reduces CDK4/6/pRb Activation and Survival of Human Neuroblastoma SH-SY5Y Cells. |
| Q28508628 | Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d |
| Q36623065 | Recent advances in neuroprotection for treating traumatic brain injury |
| Q34642738 | Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration |
| Q36778834 | Role of cell cycle proteins in CNS injury |
| Q46927043 | Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies. |
| Q30395104 | Role of p19ink4d in the pathogenesis of hearing loss |
| Q37283441 | Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma |
| Q28583941 | SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis |
| Q48316071 | Spatiotemporal Expression of EAPP Modulates Neuronal Apoptosis and Reactive Astrogliosis After Spinal Cord Injury |
| Q36509977 | TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration |
| Q41720010 | Targeting Cdk5 activity in neuronal degeneration and regeneration |
| Q83145835 | The involvement of upregulation and translocation of phospho-Rb in early neuronal apoptosis following focal cerebral ischemia in rats |
| Q40202913 | The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling |
| Q35652312 | The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease |
| Q51995718 | The transcription factor Nr2e3 functions in retinal progenitors to suppress cone cell generation. |
| Q40206111 | The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons |
| Q52151074 | Up-Regulation of CCT8 Related to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats. |
| Q45056493 | Up-regulation of ski-interacting protein in rat brain cortex after traumatic brain injury |
| Q34084964 | Visualization and quantitation of the expression of microRNAs and their target genes in neuroblastoma single cells using imaging cytometry. |
| Q38932682 | miR-146a and miR-370 coordinate enterovirus 71-induced cell apoptosis through targeting SOS1 and GADD45β. |
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