Ambivalent role of BCL6 in cell survival and transformation

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Ambivalent role of BCL6 in cell survival and transformation is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1046328068
P356DOI10.1038/SJ.ONC.1206152
P8608Fatcat IDrelease_b7ofgrjwmfbedpyofsj355yiyq
P698PubMed publication ID12555064
P5875ResearchGate publication ID10928334

P2093author name stringOlivier Albagli-Curiel
P2860cites workOverexpressed BCL6 (LAZ3) oncoprotein triggers apoptosis, delays S phase progression and associates with replication fociQ22010549
The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphomaQ24292242
A putative silencer element in the IL-5 gene recognized by Bcl6Q24300928
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3Q24313244
BAZF, a novel Bcl6 homolog, functions as a transcriptional repressorQ24522565
The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosisQ24531167
Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene productQ24554237
Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphomaQ24561494
Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemiaQ24597732
Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4Q24671741
Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1Q28139194
Two critical hits for promyelocytic leukemiaQ28139515
Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53Q28143652
Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteinsQ28187914
Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZFQ28200033
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomasQ28207345
Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogeneQ28217075
LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomasQ28255448
Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphomaQ28256118
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutaseQ28284593
Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogeneQ28295956
Disruption of the Bcl6 gene results in an impaired germinal center formationQ28509600
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammationQ28584806
Control of inflammation, cytokine expression, and germinal center formation by BCL-6Q28585541
The proto-oncogene Bc16 inhibits apoptotic cell death in differentiation-induced mouse myogenic cellsQ28589662
The Bcl-2 protein family: arbiters of cell survivalQ29618158
APM-1, a novel human gene, identified by aberrant co-transcription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activityQ29977757
A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signalingQ30828170
DNA replication progresses on the periphery of nuclear aggregates formed by the BCL6 transcription factorQ30949530
Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expressionQ33886885
Structure of a polycomb response element and in vitro binding of polycomb group complexes containing GAGA factorQ33963254
Cellular senescence: mitotic clock or culture shock?Q34019131
Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.Q34324111
McBindall--a better name for CCAAT/enhancer binding proteins?Q34432691
Regulation of gene expression by the proto-oncogene BCL-6.Q34498083
The disparity between human cell senescence in vitro and lifelong replication in vivoQ34713118
Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factorQ35203930
A short mutational hot spot in the first intron of BCL-6 is associated with increased BCL-6 expression and with longer overall survival in large B-cell lymphomasQ35788912
The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.Q36248087
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig lociQ36322298
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoproteinQ36594782
BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressorQ37477121
Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.Q37626496
The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosisQ39576033
The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.Q39725251
Target genes downregulated by the BCL-6/LAZ3 oncoprotein in mouse Ba/F3 cellsQ40807668
Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.Q40836930
Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myelomaQ40881085
Adenovirus-mediated high expression of BCL-6 in CV-1 cells induces apoptotic cell death accompanied by down-regulation of BCL-2 and BCL-X(L).Q40976625
Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cellsQ41002148
Small deletions occur in highly conserved regions of the LAZ3/BCL6 major translocation cluster in one case of non-Hodgkin's lymphoma without 3q27 translocationQ41127074
Significance of rearrangement of the BCL6 gene in B-cell lymphoid neoplasmsQ41646099
Photoreceptor development: breaking down the barriers.Q41690548
The GAGA factor of Drosophila interacts with SAP18, a Sin3-associated polypeptideQ42055789
The BCL6 gene is predominantly expressed in keratinocytes at their terminal differentiation stageQ42526807
A new functional domain of Bcl6 family that recruits histone deacetylasesQ42824972
Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactionsQ47070476
Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genesQ47982616
Increased expression of the LAZ3 (BCL6) proto-oncogene accompanies murine skeletal myogenesis.Q51092260
Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.Q52171298
The role of Bcl6 in mature cardiac myocytes.Q52173615
Purification and properties of an ATP-dependent nucleosome remodeling factor.Q52546410
Splicing factor SRP20 is a novel partner of BCL6 in a t(3;6)(q27;p21) translocation in transformed follicular lymphoma.Q53395426
Identification of negative regulatory regions within the first exon and intron of the BCL6 gene.Q53404877
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.Q55034216
B Cell Receptor Engagement and T Cell Contact Induce bcl-6 Somatic Hypermutation in Human B Cells: Identity with Ig HypermutationQ58493959
Identification of heterologous translocation partner genes fused to the BCL6 gene in diffuse large B-cell lymphomas: 5'-RACE and LA - PCR analyses of biopsy samplesQ73359146
Regulation of BCL-6 gene expression in human myeloid/monocytoid leukemic cellsQ73407905
BCL-6 is phosphorylated at multiple sites in its serine- and proline-clustered region by mitogen-activated protein kinase (MAPK) in vivoQ73428258
BCL-6 regulates chemokine gene transcription in macrophagesQ74268408
The t(2;3)(q21;q27) translocation in non-Hodgkin's lymphoma displays BCL6 mutations in the 5' regulatory region and chromosomal breakpoints distant from the geneQ77491941
Immunoglobulin (Ig)/BCL6 versus non-Ig/BCL6 gene fusion in diffuse large B-cell lymphoma corresponds to a high- versus low-level expression of BCL6 mRNAQ77854105
Molecular pathogenesis of B cell malignancy: the role of BCL-6Q77968706
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)507-516
P577publication date2003-01-01
P1433published inOncogeneQ1568657
P1476titleAmbivalent role of BCL6 in cell survival and transformation
P478volume22

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cites work (P2860)
Q25257330A new description of cellular quiescence
Q92424125Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma
Q39684544BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left-right patterning
Q39975326BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner.
Q37078872Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata
Q36544129Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and their function in breast cancer cells
Q90358222Characterizing Atypical BCL6 Signal Patterns Detected by Digital Fluorescence In Situ Hybridization (FISH) Analysis
Q35426799Comparative gene expression profiling of placentas from patients with severe pre-eclampsia and unexplained fetal growth restriction
Q36007623EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts
Q24301062Expression and clinical role of the bric-a-brac tramtrack broad complex/poxvirus and zinc protein NAC-1 in ovarian carcinoma effusions
Q33914049Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines
Q34353406Insights into gene expression changes impacting B-cell transformation: cross-species microarray analysis of bovine leukemia virus tax-responsive genes in ovine B cells
Q27642845Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain
Q33316851Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors
Q58762852STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells
Q24812693Sequence and structural analysis of BTB domain proteins
Q52085890Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.
Q39772359The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic beta-cells
Q50564001The proto-oncogene BCL6 promotes survival of olfactory sensory neurons.
Q34598347The pupal specifier broad directs progressive morphogenesis in a direct-developing insect
Q38345700Transcriptional repressor BCL-6 immortalizes germinal center-like B cells in the absence of p53 function
Q64086763Unraveling Tumor Heterogeneity in an Apparently Monolithic Disease: BCL2 and Other Players in the Genetic Landscape of Nodal Follicular Lymphoma
Q28576766ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons
Q38992318Zinc finger and BTB domain-containing protein 3 is essential for the growth of cancer cells
Q36471327miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model

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