Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia

scientific article

Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2014-03-563304
P932PMC publication ID4319237
P698PubMed publication ID25538041
P5875ResearchGate publication ID270003894

P50authorOsamu OharaQ38155071
Daisuke TomizawaQ41117632
P2093author name stringYoko Kuroki
Leonard D Shultz
Takashi Watanabe
Masatoshi Takagi
Eiichi Ishii
Katsuyoshi Koh
Kaori Sato
Atsushi Hijikata
Fumihiko Ishikawa
Mariko Eguchi
Minenori Eguchi-Ishimae
Nahoko Suzuki
Yoriko Saito
Yuki Aoki
Rintaro Ono
Shuki Mizutani
Akiko Kaneko
Saera Fujiki
P2860cites workConversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1Q24316558
Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASSQ24320097
A family of proteins that inhibit signalling through tyrosine kinase receptorsQ24336010
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineQ24614582
Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcomaQ24631455
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumorsQ24631515
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNAQ24632387
A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesionQ24647689
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cellsQ24657020
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Prognostic relevance of integrated genetic profiling in acute myeloid leukemiaQ27851726
TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study groupQ27851736
Linear models and empirical bayes methods for assessing differential expression in microarray experimentsQ27860758
hDOT1L links histone methylation to leukemogenesisQ27935809
Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47Q28138533
The SIRP family of receptors and immune regulationQ28239784
Augmented humoral and anaphylactic responses in Fc gamma RII-deficient miceQ28272701
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemiaQ28273406
Modeling the initiation and progression of human acute leukemia in miceQ28299641
Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient miceQ28513057
An Mll-dependent Hox program drives hematopoietic progenitor expansionQ28588879
Chimeric antigen receptor-modified T cells for acute lymphoid leukemiaQ29620130
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cellsQ30483569
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesisQ33604849
MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.Q33694927
Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemiaQ33868950
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.Q33887064
Trithorax group proteins: switching genes on and keeping them activeQ34235226
Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cellsQ34416761
Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cellsQ34421127
Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.Q35001583
DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesisQ35083276
Association between the polymorphism rs3217927 of CCND2 and the risk of childhood acute lymphoblastic leukemia in a Chinese populationQ35151947
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.Q35606345
MLL fusions: pathways to leukemiaQ35788362
CD24 is expressed in ovarian cancer and is a new independent prognostic marker of patient survival.Q35789342
Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children's Oncology GroupQ35848960
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenograftsQ36278046
Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3Q36293906
In search of tumor suppressing functions of meninQ36707655
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemiaQ36793806
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiationQ36893499
H3K79 methylation profiles define murine and human MLL-AF4 leukemiasQ36991857
Menin critically links MLL proteins with LEDGF on cancer-associated target genesQ37217351
Anti-CD20 antibody therapy for B-cell lymphomasQ38012522
Failure of B-cell differentiation in mice lacking the transcription factor EBF.Q38293381
CD24 controls Src/STAT3 activity in human tumors.Q39320370
Histone post-translational modifications associated to BAALC expression in leukemic cellsQ39422718
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cellsQ39620290
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpointQ39659313
CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cellsQ39878019
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell propertiesQ39965610
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitorsQ39997748
CD24 expression is a new prognostic marker in breast cancerQ40622453
Signal-regulatory protein is selectively expressed by myeloid and neuronal cells.Q41015014
A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.Q42060904
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemiaQ42616476
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infantsQ42643970
Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitroQ42973720
Definitive hematopoiesis requires the mixed-lineage leukemia geneQ44805187
SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes.Q45944230
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.Q50876705
Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.Q51918384
Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group.Q51978470
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.Q53232081
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.Q53520724
RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysisQ57016872
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemiaQ59194346
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemiasQ70905237
International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview reportQ77841177
Age-related differences in leukemia biology and prognosis: the paradigm of MLL-AF4-positive acute lymphoblastic leukemiaQ79777401
Characterization of acute lymphoblastic leukemia progenitor cellsQ80310211
Landscape of TET2 mutations in acute myeloid leukemiaQ82675574
P4510describes a project that useslimmaQ112236343
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
lymphoblastic leukemiaQ18553852
P304page(s)967-980
P577publication date2014-12-23
P1433published inBloodQ885070
P1476titleIdentification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia
P478volume125

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cites work (P2860)
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Q26770729ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies
Q64389640leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing

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