Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis (scientific article)

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

Q34681333

TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis

Q34785288

Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors

Q35232992

T-cell priming in bone marrow: the potential for long-lasting protective anti-tumor immunity

Q35601732

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

Q35849817

Tumor-targeted TNFα stabilizes tumor vessels and enhances active immunotherapy.

Q35974293

Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancer

Q36073267

Transforming growth factor beta 1 expression in human colorectal tumours: an independent prognostic marker in a subgroup of poor prognosis patients

Q36135981

First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients

Q36341084

Regulatory T cells, tumour immunity and immunotherapy

Q36430144

The correlation between colorectal cancer rates of proliferation and apoptosis and systemic cytokine levels; plus their influence upon survival

Q36614234

The highway code of T cell trafficking.

Q37045760

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer

Q37146190

Inhibitory B7-family molecules in the tumour microenvironment

Q37171804

Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma

Q37403114

The significant role of mast cells in cancer

Q37834484

Tumor microenvironment and myeloid-derived suppressor cells

Q38067642

Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma.

Q40465669

Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients.

Q42429759

Differences in T-cell immunity toward tumor-associated antigens in colorectal cancer and breast cancer patients

Q43621741

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

Q51023201

CD40L co-stimulation from CD8+ to CD4+ effector memory T cells supports CD4+ expansion.

Q51027458

The shaping of a polyvalent and highly individual T-cell repertoire in the bone marrow of breast cancer patients.

Q51790592

Chronic pancreatitis is associated with disease-specific regulatory T-cell responses.

Q51888889

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

Q51889493

Heparanase: a new metastasis-associated antigen recognized in breast cancer patients by spontaneously induced memory T lymphocytes.

Q51980538

High frequencies of functional tumor-reactive T cells in bone marrow and blood of pancreatic cancer patients.

Q51987499

Tumor necrosis factor-α is associated with positive lymph node status in patients with recurrence of colorectal cancer-indications for anti-TNF-α agents in cancer treatment.

Q53084304

Role of tumor endothelium in CD4+ CD25+ regulatory T cell infiltration of human pancreatic carcinoma.

Q53538611

Melanoma-reactive T cells in the bone marrow of melanoma patients: association with disease stage and disease duration.

Q53617680

Infectious immunological tolerance

Q54033162

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow.

Q54403966

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

Q57254166

Intratumoral Cytokines and Tumor Cell Biology Determine Spontaneous Breast Cancer-Specific Immune Responses and Their Correlation to Prognosis

Q57270774

Tumour necrosis factor and cancer

Q61819217

A note on quantifying follow-up in studies of failure time

Q71721709

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes

Q71829077

Bone marrow as a priming site for T-cell responses to blood-borne antigen

Q73791481

Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer

Q73828602

CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer

Q77168314

Change in anatomic distribution and incidence of colorectal carcinoma over a period of 15 years: clinical considerations

Q78412349

Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer

Q78962087

Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ

Q79378344

Colorectal cancer

Q81244694

Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha

Q81317318

Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy

Q84776409

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

patient

colorectal cancer

cytotoxicity

colorectal carcinoma

page(s)

739-751

P577

publication date

2014-12-22

P1433

published in

Journal of Clinical Investigation

Q3186904

P1476

title

Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis

P478

volume

125

Reverse relations

cites work (P2860)

Q26800611	Adoptive T-cell therapy for cancer: The era of engineered T cells
Q64904197	An Organoid-Based Preclinical Model of Human Gastric Cancer.
Q37130209	CIMT 2015: The right patient for the right therapy - Report on the 13th annual meeting of the Association for Cancer Immunotherapy
Q48331916	CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells
Q38838641	Checkpoint inhibition for colorectal cancer: progress and possibilities
Q37716516	Colorectal cancer cells suppress CD4+ T cells immunity through canonical Wnt signaling
Q47139326	Cordycepin and a preparation from Cordyceps militaris inhibit malignant transformation and proliferation by decreasing EGFR and IL-17RA signaling in a murine oral cancer model
Q26752374	Cytokine-Induced Modulation of Colorectal Cancer
Q40423175	Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women
Q40965334	Disease-modifying antirheumatic drugs in rheumatoid arthritis patients with a history of colorectal cancer
Q36562180	Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Q91756406	Enhanced antitumor effect of cytotoxic T lymphocytes induced by dendritic cells pulsed with colorectal cancer cell lysate expressing α-Gal epitopes
Q35673240	Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors
Q47581436	Functional T cells targeting tumor-associated antigens are predictive for recurrence-free survival of patients with radically operated non-small cell lung cancer
Q36062109	Fundamental Principles of Cancer Biology: Does it have relevance to the perioperative period?
Q89900769	Gastrointestinal tract modeling using organoids engineered with cellular and microbiota niches
Q37687316	Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells.
Q35860201	HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.
Q39294822	IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment
Q40217856	IL-10: Expanding the Immune Oncology Horizon
Q26781453	Immune cell interplay in colorectal cancer prognosis
Q51018817	Impact of the immune cell population in peripheral blood on response and survival in patients receiving neoadjuvant chemotherapy for advanced gastric cancer.
Q64256264	Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection
Q38364298	Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells
Q33711746	Initiation and Maintenance of Gastric Cancer: A Focus on CD44 Variant Isoforms and Cancer Stem Cells
Q39668561	Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8.
Q57325915	Long-peptide vaccination with driver gene mutations in p53 and Kras induces cancer mutation-specific effector as well as regulatory T cell responses
Q40987678	MHC class II tetramer analyses in AE37-vaccinated prostate cancer patients reveal vaccine-specific polyfunctional and long-lasting CD4(+) T-cells
Q90429149	Multiparametric analysis of colorectal cancer immune responses
Q36545813	OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer
Q42700802	Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection
Q57191808	Prognostic Factors for Checkpoint Inhibitor Based Immunotherapy: An Update With New Evidences
Q64268017	Prognostic value of tumor-infiltrating lymphocytes in melanoma: a systematic review and meta-analysis
Q39542382	Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes.
Q38788951	Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion.
Q93079980	Spatial and phenotypic immune profiling of metastatic colon cancer
Q58199154	Stem and immune cells in colorectal primary tumour: Number and function of subsets may diagnose metastasis
Q52320729	Strategy to targeting the immune resistance and novel therapy in colorectal cancer.
Q38835601	The Immune Revolution in Gastrointestinal Tumours: Leading the Way or Just Following?
Q26745580	The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment
Q41866457	The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
Q52679182	The Peripheral and Intratumoral Immune Cell Landscape in Cancer Patients: A Proxy for Tumor Biology and a Tool for Outcome Prediction.
Q89882588	The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis
Q47320798	The prognostic role of tumor infiltrating T-lymphocytes in squamous cell carcinoma of the head and neck: A systematic review and meta-analysis
Q41316816	Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma
Q37616487	Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer.
Q64100923	Tumor-infiltrating mucosal-associated invariant T (MAIT) cells retain expression of cytotoxic effector molecules