Polyfunctional responses by human T cells result from sequential release of cytokines

scientific article

Polyfunctional responses by human T cells result from sequential release of cytokines is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PNAS..109.1607H
P356DOI10.1073/PNAS.1117194109
P932PMC publication ID3277116
P698PubMed publication ID22160692
P5875ResearchGate publication ID51870536

P50authorDavid A. HaflerQ25004567
Douglas A. LauffenburgerQ59755238
Elizabeth M BradshawQ89698760
P2093author name stringQing Han
Neda Bagheri
J Christopher Love
P2860cites workA novel transcription factor, T-bet, directs Th1 lineage commitmentQ22253874
Nongenetic individuality in the host-phage interactionQ27333449
Systems biology of innate immunityQ28752485
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsQ29616205
Bacterial persistence as a phenotypic switchQ29618111
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania majorQ29619125
T-cell quality in memory and protection: implications for vaccine designQ30014840
Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.Q33300337
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.Q33733712
Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengravingQ34109159
A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokinesQ34281636
Digital signaling and hysteresis characterize ras activation in lymphoid cellsQ34929087
Plasticity of CD4+ T cell lineage differentiation.Q34982725
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responsesQ36229406
Heterogeneity and plasticity of T helper cellsQ36388771
Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.Q36452614
Robustness trade-offs and host-microbial symbiosis in the immune systemQ36494119
Polyfunctional T cell responses are a hallmark of HIV-2 infectionQ36618086
Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structureQ36791858
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.Q36926465
Variability and robustness in T cell activation from regulated heterogeneity in protein levelsQ37170037
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activationQ37233655
Phenotype and function of human T lymphocyte subsets: consensus and issuesQ37266382
Heterogeneity of CD4+ memory T cells: functional modules for tailored immunityQ37578374
Multiplexed Elispot assay.Q39866211
Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expressionQ40636630
Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytesQ40797290
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune responseQ41472662
Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infectionQ44753732
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cellsQ45115592
Mechanisms of T cell activation by the calcium ionophore ionomycin.Q45176412
Stochastic switching as a survival strategy in fluctuating environmentsQ46685546
IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competitionQ47644295
Expression and kinetics of cytokines determined by intracellular staining using flow cytometry.Q52035244
T-cell antigen receptor signal transductionQ59748443
Seventeen-colour flow cytometry: unravelling the immune systemQ62577376
Cytokine detection by multiplex technology useful for assessing antigen specific cytokine profiles and kinetics in whole blood cultured up to seven daysQ64131079
Visualization of antigen-specific T cell activation and cytokine expression in vivoQ71968312
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1607-1612
P577publication date2011-12-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePolyfunctional responses by human T cells result from sequential release of cytokines
P478volume109

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