Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate

scientific article published on 23 October 2015

Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELLIMM.2015.10.003
P932PMC publication ID4791071
P698PubMed publication ID26653006
P5875ResearchGate publication ID283451749

P50authorDavid W ScottQ88953752
P2093author name stringKathleen P Pratt
Yong Chan Kim
Patrick Adair
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Stochastic Cytokine Expression Induces Mixed T Helper Cell StatesQ34916338
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Cholera toxin directly enhances IL-17A production from human CD4+ T cellsQ37301166
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Intracellular complement activation sustains T cell homeostasis and mediates effector differentiationQ37397572
Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC.Q37620444
FEIBA: A Prohemostatic AgentQ37998404
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Sensitivity and resistance to regulation by IL-4 during Th17 maturationQ38771066
Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.Q39156667
Low-strength T-cell activation promotes Th17 responses.Q39338146
CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammationQ40707024
T cell activation determined by T cell receptor number and tunable thresholds.Q41186277
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Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.Q41517191
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Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammationQ41889460
Negative selection of T cells occurs throughout thymic developmentQ42058405
Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiationQ42060819
Human T cells that are able to produce IL-17 express the chemokine receptor CCR6.Q45054355
CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.Q45332832
Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIII.Q45864619
Disappearance of inhibitor to factor VIII in HIV-infected hemophiliacs with progression to AIDS or severe ARC.Q45883973
Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth InfectionQ47573482
Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.Q48009840
Changes in histone H4 acetylation during in vivo versus in vitro maturation of equine oocytesQ48659470
The critical role of Th1-dominant immunity in tumor immunology.Q52025034
A probabilistic view of immunology: drawing parallels with physicsQ53557797
Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cellsQ58882233
Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoformsQ71735219
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1Q80991137
P304page(s)30-41
P577publication date2015-10-23
P1433published inCellular ImmunologyQ2597167
P1476titleAvidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate
P478volume299

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cites work (P2860)
Q45875104From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance
Q36386393Naïve helper T cells with high CD5 expression have increased calcium signaling.

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