| Q36029113 | 1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept |
| Q47637581 | A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia. |
| Q92377668 | A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade |
| Q73933740 | A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies |
| Q103728305 | A T-cell reporter platform for high-throughput and reliable investigation of TCR function and biology |
| Q28145380 | A cellular calculus for signal integration by T cells |
| Q42405718 | A comparative study of colorimetric cell proliferation assays in immune cells |
| Q40868763 | A comprehensive characterization of the T-cell antigen receptor complex composition by microcapillary liquid chromatography-tandem mass spectrometry |
| Q41672361 | A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory |
| Q33542325 | A kinetic differentiation model for the action of altered TCR ligands. |
| Q36454568 | A logical analysis of T cell activation and anergy |
| Q52070755 | A mathematical analysis of TCR serial triggering and down-regulation. |
| Q36400491 | A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor beta chain and major histocompatibility complex class II. |
| Q34144494 | A sharp T-cell antigen receptor signaling threshold for T-cell proliferation |
| Q36389642 | A simple mechanistic explanation for original antigenic sin and its alleviation by adjuvants |
| Q35016200 | A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding |
| Q77637318 | A yeast surface display system for the discovery of ligands that trigger cell activation |
| Q36438067 | AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation |
| Q38737500 | ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis |
| Q44404221 | Absence of co-stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo |
| Q45865669 | Activation of lymphocytes by anti-CD3 single-chain antibody dimers expressed on the plasma membrane of tumor cells |
| Q73925265 | Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation |
| Q30437670 | Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model |
| Q47668716 | Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells |
| Q28076866 | Advances in Molecular Imaging Strategies for In Vivo Tracking of Immune Cells |
| Q37966022 | Advances in direct T-cell alloreactivity: function, avidity, biophysics and structure |
| Q73835283 | Age-dependent T cell tolerance and autoimmunity to myelin basic protein |
| Q63361361 | Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation |
| Q40106402 | Allosteric changes in the TCR/CD3 structure upon interaction with extra- or intra-cellular ligands |
| Q56908557 | Altered expression of various receptors on T cells in young and old mice after mitogenic stimulation: a flow cytometric analysis |
| Q41903218 | Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors |
| Q77353755 | Altered peptide ligands and wild-type peptide induce indistinguishable responses of a human Th0 clone |
| Q53805171 | Altered superantigenic ligands demonstrate the quantitative nature of T-cell activation. |
| Q60089786 | Alternative pathways for the selection of antigen-specific peripheral T cells |
| Q43760311 | An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL. |
| Q52655475 | An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination. |
| Q27860698 | Analysis of successful immune responses in persons infected with hepatitis C virus |
| Q52534683 | Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. |
| Q33560416 | Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice |
| Q34263452 | Antigen decoding by T lymphocytes: from synapses to fate determination |
| Q44555210 | Antigen presentation on MHC molecules as a diversity filter that enhances immune efficacy |
| Q37262408 | Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity |
| Q36979111 | Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane. |
| Q40920081 | Antigen-induced TCR-CD3 down-modulation does not require CD3delta or CD3gamma cytoplasmic domains, necessary in response to anti-CD3 antibody |
| Q73166239 | Antigen-specific elimination of T cells induced by oligomerized hemagglutinin (HA) 306-318 |
| Q37597112 | Antigen-stimulated dissociation of BCR mIg from Ig-alpha/Ig-beta: implications for receptor desensitization |
| Q35212646 | Antiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements |
| Q77790265 | Associations of metrics of peak inhalation exposure and skin exposure indices with beryllium sensitization at a beryllium manufacturing facility |
| Q36935749 | At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy |
| Q53594266 | Autoantibodies against CD28 are associated with atopic diseases. |
| Q34418068 | Autoreactivity, dynamic tuning and selectivity |
| Q36684961 | Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate |
| Q36251289 | Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance |
| Q38129635 | B7 family checkpoint regulators in immune regulation and disease |
| Q37022838 | B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells |
| Q50033143 | Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia |
| Q38044759 | Belatacept: a new era of immunosuppression? |
| Q51823145 | Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex. |
| Q33933213 | Bispecific antibodies for treatment of cancer in experimental animal models and man. |
| Q36471557 | Blockade of Programmed Death 1 Augments the Ability of Human T Cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer. |
| Q38255765 | Blockade of co-stimulation in chronic inflammatory diseases |
| Q36501106 | Blood and milk cellular immune responses of mastitic non-periparturient cows inoculated with Staphylococcus aureus |
| Q42947201 | CD2 sets quantitative thresholds in T cell activation |
| Q47733468 | CD28 affects the earliest signaling events generated by TCR engagement |
| Q40761126 | CD28 as a molecular amplifier extending TCR ligation and signaling capabilities. |
| Q34775828 | CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76? |
| Q40900024 | CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens |
| Q34049974 | CD28, CTLA-4 and their ligands: who does what and to whom? |
| Q73589571 | CD28-B7 costimulation: a critical role for initiation and development of experimental autoimmune neuritis in C57BL/6 mice |
| Q34543577 | CD28-mediated co-stimulation: a quantitative support for TCR signalling |
| Q42490100 | CD28/CTLA-4 and CD80/CD86 costimulatory molecules are mainly involved in acceptance or rejection of human liver transplant |
| Q24804208 | CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis |
| Q42552884 | CD43 regulates the threshold for T cell activation by targeting Cbl functions |
| Q37184070 | CD8+ T cell efficacy in vaccination and disease |
| Q34738334 | CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics |
| Q30478206 | CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse |
| Q47424017 | CTLA-4: a moving target in immunotherapy. |
| Q33855058 | CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris |
| Q40806098 | Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70. |
| Q34862177 | Cell adhesion and polarity during immune interactions |
| Q60397576 | Cells’ Perception of Position in a Concentration Gradient |
| Q34009665 | Cellular and humoral immune responses to Borrelia burgdorferi antigens in patients with culture-positive early Lyme disease |
| Q35583494 | Cell‐cycle regulation of T‐cell responses – novel approaches to the control of alloimmunity |
| Q38011650 | Challenges in T cell receptor gene therapy. |
| Q35361010 | Characterisation of mucosal lymphoid aggregates in ulcerative colitis: immune cell phenotype and TcR-gammadelta expression |
| Q36490768 | Checkpoint blockade in cancer immunotherapy |
| Q47604342 | Chemokine Signaling Facilitates Early-Stage Breast Cancer Survival and Invasion through Fibroblast-Dependent Mechanisms |
| Q26796099 | Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells? |
| Q28271806 | Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily |
| Q73115340 | Collaboration of TCR-, CD4- and CD28-mediated signalling in antigen-specific MHC class II-restricted T-cells |
| Q63382913 | Comparison of in vitro immunostimulatory potential of live and inactivated influenza viruses |
| Q33423703 | Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses |
| Q24646649 | Control of NFATx1 nuclear translocation by a calcineurin-regulated inhibitory domain |
| Q36717167 | Control of T cell antigen reactivity via programmed TCR downregulation. |
| Q32065338 | Controlling duration of contact between T cells and antigen-presenting cells |
| Q35894714 | Cooperative enhancement of specificity in a lattice of T cell receptors |
| Q51905872 | Coreceptor CD8-driven modulation of T cell antigen receptor specificity. |
| Q37375148 | Costimulation Blockade in Kidney Transplantation: An Update |
| Q36380864 | Costimulation by B7 modulates specificity of cytotoxic T lymphocytes: a missing link that explains some bystander T cell activation. |
| Q33971036 | Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses |
| Q37685171 | Costimulation signals for memory CD8+ T cells during viral infections |
| Q41495234 | Costimulation, tolerance and ignorance of cytolytic T lymphocytes in immune responses to tumor antigens |
| Q73065666 | Cross-antagonism of a T cell clone expressing two distinct T cell receptors |
| Q34249351 | Cross-reactivity in T-cell antigen recognition |
| Q35583529 | Crossing the bridge: large animal models in translational transplantation research |
| Q40889971 | Culture of human T cells in stirred bioreactors for cellular immunotherapy applications: shear, proliferation, and the IL-2 receptor |
| Q37308343 | Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I decay rates |
| Q41897237 | Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells |
| Q34001315 | Cytotoxic T-cell-mediated response against Yersinia pseudotuberculosis in HLA-B27 transgenic rat. |
| Q30458953 | DNA Replication and Cell Cycle Progression Regulatedby Long Range Interaction between Protein Complexes bound to DNA |
| Q46517603 | Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction |
| Q39349502 | Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. |
| Q74071794 | Dependence of T cell activation on area of contact and density of a ligand-coated surface |
| Q42946982 | Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex |
| Q47547004 | Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression. |
| Q45755895 | Development of CD8+ T cells expressing two distinct receptors specific for MTB and HIV-1 peptides. |
| Q41834240 | Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells |
| Q27469939 | Different Levels of T-Cell Receptor Triggering Induce Distinct Functions in Hepatitis B and Hepatitis C Virus-Specific Human CD4+ T-Cell Clones |
| Q33540756 | Differential signalling by variant ligands of the T cell receptor and the kinetic model of T cell activation |
| Q24291651 | Differentiation of regulatory T cells 1 is induced by CD2 costimulation |
| Q33300337 | Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression. |
| Q37857379 | Dimeric MHC-peptides inserted into an immunoglobulin scaffold as new immunotherapeutic agents |
| Q36066378 | Distinct CD4+ helper T cells involved in primary and secondary responses to infection. |
| Q45756411 | Distinct patterns of T cell receptor distribution of peripheral blood CD8+ cells during different stages of chronic infection with hepatitis B virus |
| Q73838333 | Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation |
| Q44583955 | Distinctive response of naïve lymphocytes from cord blood to primary activation via TCR. |
| Q74541572 | Diverse patterns of unresponsiveness in an acetylcholine receptor-specific T-cell clone from a myasthenia gravis patient after engaging the T-cell receptor with three different ligands |
| Q35085517 | Diverse roles of integrins in human T lymphocyte biology |
| Q37382898 | Downregulation of T cell receptor expression by CD8(+) lymphocytes in kidney allografts |
| Q71930197 | Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor |
| Q35175877 | Duration of antigen availability influences the expansion and memory differentiation of T cells |
| Q42088119 | Dynamic changes during the immune response in T cell-antigen-presenting cell clusters isolated from lymph nodes. |
| Q39506116 | Dysregulated synthesis of intracellular type 1 and type 2 cytokines by T cells of patients with cutaneous T-cell lymphoma. |
| Q36978926 | Early Gag immunodominance of the HIV-specific T-cell response during acute/early infection is associated with higher CD8+ T-cell antiviral activity and correlates with preservation of the CD4+ T-cell compartment. |
| Q45737915 | Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination |
| Q45664914 | Early impairment of CD8+ T cells immune response against Epstein-Barr virus (EBV) antigens associated with high level of circulating mononuclear EBV DNA load in HIV infection. |
| Q38160477 | Emerging Co-signaling Networks in T Cell Immune Regulation |
| Q42996261 | Endogenous oxygen radicals modulate protein tyrosine phosphorylation and JNK-1 activation in lectin-stimulated thymocytes. |
| Q41633118 | Endosomal proteases and antigen processing |
| Q24291774 | Endothelial cell costimulation of T cell activation through CD58-CD2 interactions involves lipid raft aggregation |
| Q24805981 | Endothelial cells present antigens in vivo |
| Q33889480 | Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains |
| Q38290031 | Engineering CAR-T cells: Design concepts |
| Q40628569 | Enhanced Effector and Memory CTL Responses Generated by Incorporation of Receptor Activator of NF-κB (RANK)/RANK Ligand Costimulatory Molecules into Dendritic Cell Immunogens Expressing a Human Tumor-Specific Antigen |
| Q37702226 | Enhanced T cell receptor gene therapy for cancer |
| Q36286122 | Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond. |
| Q36286127 | Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability |
| Q47770806 | Estimation of maximal affinities between T-cell receptors and MHC/peptide complexes |
| Q34895151 | Evasion of host immunity directed by papillomavirus-encoded proteins |
| Q37089122 | Ever closer to a prophylactic vaccine for HCV. |
| Q36368219 | Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs |
| Q73968904 | FD-891, a structural analogue of concanamycin A that does not affect vacuolar acidification or perforin activity, yet potently prevents cytotoxic T lymphocyte-mediated cytotoxicity through the blockage of conjugate formation |
| Q42876926 | Fine tuning and efficient T cell activation with stimulatory aCD3 nanoarrays. |
| Q77879944 | Flow cytometry used for the analysis of calcium signaling induced by antigen-specific T-cell activation |
| Q37376774 | Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response |
| Q30474720 | Force measurements of TCR/pMHC recognition at T cell surface |
| Q52237316 | Formation of TCR dimers/trimers as a crucial step for T cell activation. |
| Q74179369 | Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists |
| Q57363708 | From TCR Engagement to T Cell Activation |
| Q33840553 | From synapses to immunological memory: the role of sustained T cell stimulation |
| Q37406665 | From tango to quadrilla: current views of the immunological synapse. |
| Q26772337 | Functional Heterogeneity in CD4(+) T Cell Responses Against a Bacterial Pathogen |
| Q38066211 | Functional avidity: a measure to predict the efficacy of effector T cells? |
| Q33179769 | Functional balance between T cell chimeric receptor density and tumor associated antigen density: CTL mediated cytolysis and lymphokine production |
| Q35064049 | Functional differences between memory and naive CD8 T cells |
| Q58544663 | Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity |
| Q78177482 | Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level. |
| Q34489534 | Genetic defects in N-glycosylation and cellular diversity in mammals |
| Q24642718 | Genetic engineering of T cells for adoptive immunotherapy |
| Q73798529 | Genetic regulation of the impaired immune response to hepatitis-B vaccine associated with low TCR density in end stage renal disease patients: contribution of complement C4 and factor B alleles |
| Q36170773 | HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation |
| Q37592165 | Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells |
| Q35102246 | Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations |
| Q35675262 | Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: implications for autoimmunity |
| Q47933380 | Heterogeneity in the clonal T cell response. Implications for models of T cell activation and cytokine phenotype development. |
| Q42110508 | High efficiency gene transfer is an efficient way of defining therapeutic targets: a functional genomics approach |
| Q51875172 | How T-cells use large deviations to recognize foreign antigens. |
| Q43695965 | How much TCR does a T cell need? |
| Q33181641 | Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells |
| Q33814659 | Human immunodeficiency virus type 2 produces a defect in CD3-gamma gene transcripts similar to that observed for human immunodeficiency virus type 1. |
| Q57445880 | Human population-based identification of CD4+ T-cell peptide epitope determinants |
| Q52035503 | ICAM-1 and B7-1 provide similar but distinct costimulation for CD8+ T cells, while CD4+ T cells are poorly costimulated by ICAM-1. |
| Q77650404 | IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules |
| Q47273387 | IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. |
| Q30835465 | Identification of selectively expressed genes and antigens in CTCL. |
| Q33225554 | Identification of the tumor cells in peripheral T-cell lymphomas by combined polymerase chain reaction-based T-cell receptor beta spectrotyping and immunohistological detection with T-cell receptor beta chain variable region segment-specific antibod |
| Q42991769 | Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: new prospects for an HCV vaccine |
| Q41701856 | Immunological ignorance of silent antigens as an explanation of tumor evasion |
| Q37864698 | Immunological perspective of self versus tumor antigens: insights from the RIP-gp model. |
| Q34609440 | Immunological principles of T-cell-mediated adverse drug reactions in skin |
| Q36253506 | Immunoregulation by tumor necrosis factor superfamily member LIGHT |
| Q48028076 | Immunotherapy and breast cancer |
| Q74569068 | Immunotherapy through TCR gene transfer |
| Q52041456 | In vitro responses of human CD45R0brightRA- and CD45R0-RAbright T cell subsets and their relationship to memory and naive T cells. |
| Q35783661 | In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation |
| Q40715343 | Increased functional expression of transgene in primary human lymphocytes using retroviral vectors modified with IRES and splicing motifs |
| Q41710829 | Individual T cells hold unexpected clues to the nature of anergy and memory |
| Q36400784 | Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. |
| Q61651912 | Induction of T cell anergy by liposomes with incorporated major histocompatibility complex (MHC) II/peptide complexes |
| Q58598501 | Influence of correlated antigen presentation on T-cell negative selection in the thymus |
| Q24814725 | Interaction between human lung fibroblasts and T-lymphocytes prevents activation of CD4+ cells. |
| Q34198880 | Interaction of T cells with APCs: the serial encounter model |
| Q78455972 | Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction |
| Q61863515 | Interferon-gamma administration after abdominal surgery rescues antigen-specific helper T cell immune reactivity |
| Q73065660 | Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function |
| Q28512242 | Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement |
| Q37864700 | Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family |
| Q41341624 | Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation |
| Q24642984 | Kinetics and extent of protein tyrosine kinase activation in individual T cells upon antigenic stimulation |
| Q34572115 | Knockout mice: a paradigm shift in modern immunology |
| Q42223573 | LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ. |
| Q42519424 | Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling |
| Q74086295 | Ligation of human CD4 interferes with antigen-induced activation of primary T cells |
| Q36447773 | Lipid rafts in lymphocyte activation and migration |
| Q30458948 | Long Range Force between Pre-Replication Complexes (Pre-RC) in DNA Controls Replication and Cell Cycle Progression |
| Q26781296 | Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response |
| Q51047946 | Lowering TCR expression on naive CD8+ T cells does not affect memory T-cell differentiation. |
| Q30479335 | MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo |
| Q34509937 | MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo |
| Q41594043 | MHC class II-dependent peptide antigen versus superantigen presentation to T cells |
| Q40938931 | MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition |
| Q33805040 | Major histocompatibility complex class II antigen presentation in Hodgkin's disease |
| Q36400215 | Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities |
| Q73024064 | Major histocompatibility complex class II- fetal skin dendritic cells are potent accessory cells of polyclonal T-cell responses |
| Q41457016 | Making the T cell receptor go the distance: a topological view of T cell activation |
| Q38839628 | Manipulating Memory CD8 T Cell Numbers by Timed Enhancement of IL-2 Signals |
| Q30633083 | Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling |
| Q33960119 | Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation |
| Q34678846 | Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation |
| Q44479360 | Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation |
| Q31677352 | Membrane raft association of CD47 is necessary for actin polymerization and protein kinase C theta translocation in its synergistic activation of T cells |
| Q37408575 | Memory T cells need CD28 costimulation to remember |
| Q34160024 | Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel |
| Q30843475 | Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival |
| Q45735085 | Modeling the T-helper cell response in acute and chronic hepatitis B virus infection using T-cell receptor transgenic mice |
| Q36963201 | Modulating co-stimulation |
| Q24535662 | Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors |
| Q36767508 | Modulation of the immunological synapse: a key to HIV-1 pathogenesis? |
| Q42812329 | Molecular interpretation of ERK signal duration by immediate early gene products |
| Q35096668 | Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. |
| Q52020886 | Most parasite-specific CD8+ cells in Trypanosoma cruzi-infected chronic mice are down-regulated for T-cell receptor-alphabeta and CD8 molecules. |
| Q35690841 | Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers. |
| Q24793730 | Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases |
| Q35000179 | Multivalent structure of an alphabetaT cell receptor |
| Q73808233 | Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation |
| Q38358215 | Negative regulation of T cell activation by placental protein 14 is mediated by the tyrosine phosphatase receptor CD45. |
| Q32058522 | Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation |
| Q35176440 | New designs for cancer vaccine and artificial veto cells: an emerging palette of protein paints |
| Q28362330 | Non FcR-binding murine antihuman CD3 monoclonal antibody is capable of productive TCR signalling and induces proliferation in the presence of costimulation |
| Q47927425 | Non-responsiveness of antigen-experienced CD4 T cells reflects more stringent co-stimulatory requirements |
| Q39592749 | Nondeletional T-cell receptor transgenic mice: model for the CD4(+) T-cell repertoire in chronic hepatitis B virus infection |
| Q40906220 | Origin, maturation and antigen presenting function of dendritic cells. |
| Q34557896 | PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells |
| Q36402354 | PKCtheta signals activation versus tolerance in vivo |
| Q37401020 | PU.1 regulates TCR expression by modulating GATA-3 activity. |
| Q40990067 | Paralysis of B7 co-stimulation through the effect of viral IL-10 on T cells as a mechanism of local tolerance induction |
| Q62083013 | Partial agonism and independent modulation of T cell receptor and CD8 in hapten-specific cytotoxic T cells |
| Q73814851 | Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation |
| Q36381014 | Persistence of peptide-induced CD4+ T cell anergy in vitro |
| Q46214811 | Phenotypic models of T cell activation |
| Q48260911 | Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse |
| Q26744638 | Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation |
| Q42412360 | Phosphorylation of Bcl10 negatively regulates T-cell receptor-mediated NF-kappaB activation |
| Q37763999 | Plasticity in programming of effector and memory CD8 T-cell formation |
| Q36401714 | Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor |
| Q37637869 | Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex |
| Q45868559 | Practical considerations for chimeric antigen receptor design and delivery |
| Q27312237 | Predictive models of type 1 diabetes progression: understanding T-cell cycles and their implications on autoantibody release |
| Q36376999 | Presentation of a T cell receptor antagonist peptide by immunoglobulins ablates activation of T cells by a synthetic peptide or proteins requiring endocytic processing |
| Q37122367 | Primate models in organ transplantation |
| Q52011668 | Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. |
| Q77378708 | Prolactin receptor signaling: shared components with the T-cell antigen receptor in Nb2 lymphoma cells |
| Q36400848 | Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides |
| Q40826872 | Quantitation of HLA-A*0201 bound tumor associated antigens on a peptide pulsed B cell line |
| Q41876221 | Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering |
| Q38483976 | Quantitative interplay between activating and pro-apoptotic signals dictates T cell responses |
| Q39677483 | Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses |
| Q34819446 | Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells |
| Q39831149 | Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated plasmodium falciparum malaria. |
| Q34245432 | Receptor clustering and transmembrane signaling in T cells |
| Q40802102 | Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation |
| Q39549411 | Recombinant Marek's disease virus (MDV)-derived lymphoblastoid cell lines: regulation of a marker gene within the context of the MDV genome. |
| Q34166288 | Redirecting T cells to Ewing's sarcoma family of tumors by a chimeric NKG2D receptor expressed by lentiviral transduction or mRNA transfection |
| Q41739207 | Regulation of TCR-induced IFN-gamma release from islet-reactive non-obese diabetic CD8(+) T cells by prostaglandin E(2) receptor signaling |
| Q73153290 | Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse |
| Q43824396 | Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells |
| Q42259452 | Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells |
| Q33908248 | Response of naïve and memory CD8+ T cells to antigen stimulation in vivo |
| Q36376671 | Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells |
| Q33835246 | Role of CD28/CD80-86 and CD40/CD154 costimulatory interactions in host defense to primary herpes simplex virus infection |
| Q38572497 | Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets |
| Q34337765 | Role of adhesion molecules in activation signaling in T lymphocytes |
| Q28143038 | Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes |
| Q43952453 | Serial triggering of T cell receptors results in incremental accumulation of signaling intermediates |
| Q24642763 | Serological identification and expression analysis of gastric cancer-associated genes |
| Q41642426 | Serological identification of human tumor antigens |
| Q37055402 | Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication |
| Q41949853 | Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions |
| Q28755947 | Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells |
| Q42505897 | Specific overexpression of rheumatoid arthritis-associated HLA-DR alleles and presentation of low-affinity peptides |
| Q44612273 | Splice variant in TCRζ links T cell receptor signaling to a G-protein-related signaling pathway |
| Q37339632 | Standardization and cross validation of alloreactive IFNγ ELISPOT assays within the clinical trials in organ transplantation consortium |
| Q51115632 | Stochastic modelling of T-cell activation. |
| Q84343886 | Strains of Mycobacterium avium differentially activate human dendritic cells |
| Q56959542 | Strategies for immunoprophylaxis and immunotherapy of papillomaviruses |
| Q35583489 | Surface T‐cell antigen receptor expression and availability for long‐term antigenic signaling |
| Q83352516 | Sustained B7/CD28 interactions and resultant phosphatidylinositol 3-kinase activity maintain G1-->S phase transitions at an optimal rate |
| Q35553745 | Synthesis, stability, and subcellular distribution of major histocompatibility complex class II molecules in Langerhans cells infected with Leishmania major. |
| Q36975786 | Synthetic mixed-signal computation in living cells |
| Q73134915 | T cell fitness determined by signal strength |
| Q41642381 | T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs |
| Q33676064 | T cell receptor usage in infectious disease |
| Q41107397 | T cell receptor α‐chain tail is required for protein kinase C‐mediated down‐regulation, but not for signaling |
| Q37787987 | T cell responses in lymph nodes |
| Q24291521 | T cell signal transduction and the role of CD7 in costimulation |
| Q30969240 | T cell-dendritic cell interaction in vivo: random encounters favor development of long-lasting ties |
| Q37527634 | T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis |
| Q34414412 | T cells take aim at cancer |
| Q36376680 | T helper subset differentiation in the absence of invariant chain |
| Q38898439 | T lymphocytes need less than 3 min to discriminate between peptide MHCs with similar TCR-binding parameters |
| Q52668512 | T-bet promotes potent antitumor activity of CD4+ CAR T cells. |
| Q35127621 | T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. |
| Q77419342 | T-cell anergy induced by clonotype-specific antibodies: modulation of an autoreactive human T-cell clone in vitro |
| Q36972497 | T-cell co-stimulatory pathways in autoimmunity |
| Q34691040 | T-cell growth, cell surface organization, and the galectin-glycoprotein lattice |
| Q30014840 | T-cell quality in memory and protection: implications for vaccine design |
| Q34572202 | T-cell regulation by CD28 and CTLA-4. |
| Q41642337 | T-cell signaling: the importance of receptor clustering |
| Q34716347 | T-cell signalling and autoimmunity: molecular mechanisms of disease |
| Q34718133 | T-cell-receptor gene therapy |
| Q26772704 | TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation |
| Q39540572 | TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections |
| Q35877202 | TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response |
| Q58581671 | TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen-induced T cell activation |
| Q56888810 | Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative |
| Q77383438 | Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy |
| Q35037678 | Targeting tumours with genetically enhanced T lymphocytes |
| Q36631585 | Telomerase is involved in IL-7-mediated differential survival of naive and memory CD4+ T cells |
| Q34575331 | The B7-CD28 superfamily |
| Q33878809 | The MHC class II ligand lymphocyte activation gene-3 is co-distributed with CD8 and CD3-TCR molecules after their engagement by mAb or peptide-MHC class I complexes |
| Q56112107 | The Phosphorylation State of CD3γ Influences T Cell Responsiveness and Controls T Cell Receptor Cycling |
| Q38388590 | The Role of Anti-PD-1/PD-L1 Agents in Melanoma: Progress to Date |
| Q58689503 | The Roles of CD4+ T Cells in Tumor Immunity |
| Q46014500 | The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection. |
| Q34264026 | The amplification of TCR signaling by dynamic membrane microdomains |
| Q36367978 | The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model |
| Q40788843 | The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep. |
| Q41870329 | The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses |
| Q51099389 | The duration of antigenic stimulation determines the fate of naive and effector T cells. |
| Q28306549 | The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway |
| Q47973646 | The expression of co-stimulatory and accessory molecules on cultured human muscle cells is not dependent on stimulus by pro-inflammatory cytokines: relevance for the pathogenesis of inflammatory myopathy |
| Q38034268 | The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes. |
| Q37108443 | The great balancing act: regulation and fate of antiviral T-cell interactions |
| Q40767962 | The immunological synapse and CD28-CD80 interactions. |
| Q33958592 | The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. |
| Q30052356 | The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors |
| Q24675300 | The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis |
| Q36290302 | The many sounds of T lymphocyte silence. |
| Q45065835 | The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity |
| Q74179334 | The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells |
| Q36877341 | The molecular makeup and function of regulatory and effector synapses |
| Q38564920 | The multifaceted role of PIP2 in leukocyte biology. |
| Q38541019 | The pharmacology of second-generation chimeric antigen receptors. |
| Q36371248 | The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering |
| Q24803143 | The quantal theory of how the immune system discriminates between "self and non-self" |
| Q36391829 | The quantal theory of immunity |
| Q26999436 | The role of T cell receptor signaling thresholds in guiding T cell fate decisions |
| Q37803117 | The roles of c‐rel and interleukin‐2 in tolerance: a molecular explanation of self–nonself discrimination |
| Q36376819 | The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex |
| Q41762464 | The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse |
| Q57228048 | The threshold for autoimmune T cell killing is influenced by B7-1 |
| Q37501186 | Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways |
| Q37434613 | Transient alteration of T cell fine specificity by a strong primary stimulus correlates with T cell receptor down-regulation |
| Q37042924 | Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice |
| Q40932922 | Translocation of tyrosine-phosphorylated TCRzeta chain to glycolipid-enriched membrane domains upon T cell activation |
| Q38017160 | Transplant immunology for non-immunologist |
| Q37224026 | Transplantation tolerance: fooling mother nature |
| Q56922108 | Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism |
| Q74570647 | Truncation of the neuritogenic peptide bP2(60-70) results in the generation of altered peptide ligands with the potential to interfere with T cell activation |
| Q60542078 | Tumor Vasculature Targeted Therapies |
| Q35155955 | Tumors as elusive targets of T-cell-based active immunotherapy |
| Q44619554 | Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining |
| Q44327053 | Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures |
| Q45720900 | Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4⁺ T cells. |
| Q41512249 | Understanding the mechanisms of sustained signaling and T cell activation |
| Q34514254 | Unraveling the contribution of pancreatic beta-cell suicide in autoimmune type 1 diabetes |
| Q73296012 | Up-regulation of human epidermal Langerhans' cell B7-1 and B7-2 co-stimulatory molecules in vivo by solar-simulating irradiation |
| Q28584882 | VSIG4, a B7 family-related protein, is a negative regulator of T cell activation |
| Q37170037 | Variability and robustness in T cell activation from regulated heterogeneity in protein levels |
| Q36769225 | mTOR at the crossroads of T cell proliferation and tolerance |