scholarly article | Q13442814 |
P819 | ADS bibcode | 2013PLoSO...881221C |
P356 | DOI | 10.1371/JOURNAL.PONE.0081221 |
P932 | PMC publication ID | 3849145 |
P698 | PubMed publication ID | 24312539 |
P5875 | ResearchGate publication ID | 259208980 |
P50 | author | Carlos Palacio | Q83011236 |
Francesc Bosch | Q53260145 | ||
Marta Crespo | Q42037673 | ||
Josep Castellvi | Q42648101 | ||
P2093 | author name string | Pau Abrisqueta | |
Noelia Purroy | |||
Cecilia Carpio | |||
Eva Calpe | |||
Júlia Carabia | |||
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Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a | Q80319155 | ||
ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL) | Q81583965 | ||
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Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine | Q44484570 | ||
ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. | Q44605532 | ||
ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia | Q44859885 | ||
ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia | Q46112511 | ||
ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. | Q51119490 | ||
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells. | Q53336736 | ||
BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells. | Q53476669 | ||
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Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia | Q24599100 | ||
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) | Q24677007 | ||
Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical | Q24681992 | ||
BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially | Q28204940 | ||
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells | Q33830733 | ||
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo | Q34029869 | ||
Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior | Q34095636 | ||
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia | Q34249777 | ||
A combination of cytokines rescues highly purified leukemic CLL B-cells from spontaneous apoptosis in vitro | Q34653811 | ||
Role of the microenvironment in chronic lymphocytic leukaemia | Q35583432 | ||
Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha | Q35847913 | ||
B cell antigen receptor engagement inhibits stromal cell-derived factor (SDF)-1alpha chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4. | Q36368196 | ||
ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia | Q36478480 | ||
B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406. | Q37028635 | ||
Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA | Q37207766 | ||
The microenvironment in mature B-cell malignancies: a target for new treatment strategies | Q37563816 | ||
Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions | Q38049970 | ||
ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation | Q39485051 | ||
Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG4 antibody immunotoxin | Q40383626 | ||
Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. | Q40420056 | ||
Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib | Q41763842 | ||
Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach | Q42191925 | ||
Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration | Q42221150 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | B-cell | Q188930 |
P304 | page(s) | e81221 | |
P577 | publication date | 2013-12-03 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | ZAP-70 promotes the infiltration of malignant B-lymphocytes into the bone marrow by enhancing signaling and migration after CXCR4 stimulation | |
P478 | volume | 8 |
Q35781372 | Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo |
Q38237648 | Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types? |
Q42363684 | Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia |
Q40486626 | Syndecan-1 increases B-lymphoid cell extravasation in response to HIV-1 Tat via αvβ3/pp60src/pp125FAK pathway |
Q47960121 | The role of G protein-coupled receptors in lymphoid malignancies |
Q37618829 | The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system |