scholarly article | Q13442814 |
P819 | ADS bibcode | 2006PNAS..10315073E |
P356 | DOI | 10.1073/PNAS.0607332103 |
P8608 | Fatcat ID | release_myywllxlsndfbfg4igkycotite |
P932 | PMC publication ID | 1586178 |
P698 | PubMed publication ID | 17015833 |
P5875 | ResearchGate publication ID | 6778922 |
P50 | author | Helena Backvall | Q76400253 |
Vilhelm A. Bohr | Q89667423 | ||
Barbara Gilchrest | Q93373562 | ||
P2093 | author name string | Mark S Eller | |
Patricia L Opresko | |||
Xiaodong Liao | |||
Helena Bäckvall | |||
Kendra Hanna | |||
SuiYang Liu | |||
P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex | Q24298863 | ||
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes | Q24302611 | ||
A human telomeric protein | Q24304466 | ||
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases | Q24304488 | ||
Nucleolar localization of the Werner syndrome protein in human cells | Q24323083 | ||
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides | Q24793800 | ||
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2 | Q24793970 | ||
TRF2 Protects Human Telomeres from End-to-End Fusions | Q28111898 | ||
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2 | Q28116237 | ||
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
The Werner syndrome protein: an update | Q28138573 | ||
How to activate p53 | Q28143809 | ||
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway | Q28203777 | ||
Telomere length regulation | Q28290143 | ||
Senescence Induced by Altered Telomere State, Not Telomere Loss | Q28315731 | ||
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion | Q28507823 | ||
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
The Werner syndrome protein: an update | Q29544598 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
DNA damage foci at dysfunctional telomeres | Q29614811 | ||
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity | Q29615388 | ||
A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
Protection of mammalian telomeres | Q29618391 | ||
Stimulation of melanogenesis by DNA oligonucleotides: effect of size, sequence and 5' phosphorylation | Q31871227 | ||
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle | Q33227804 | ||
Human telomeres maintain their overhang length at senescence | Q33707650 | ||
Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks | Q33957738 | ||
Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process. | Q34200511 | ||
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype | Q34233470 | ||
TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA. | Q34288672 | ||
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status | Q34441492 | ||
Evidence that exposure of the telomere 3' overhang sequence induces senescence | Q34470102 | ||
Telomere dysfunction: multiple paths to the same end. | Q34535652 | ||
Phosphorylation of H2AX at short telomeres in T cells and fibroblasts | Q34550319 | ||
In vivostability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides | Q35012323 | ||
Reversal of human cellular senescence: roles of the p53 and p16 pathways | Q35561999 | ||
Senescence and immortalization: role of telomeres and telomerase | Q35912152 | ||
A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo | Q36381814 | ||
Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice. | Q37095361 | ||
Induction of apoptosis by telomere 3' overhang-specific DNA. | Q38288992 | ||
Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides | Q38334543 | ||
Induction of a p95/Nbs1-mediated S phase checkpoint by telomere 3' overhang specific DNA. | Q38358265 | ||
The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro | Q38361135 | ||
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. | Q40481955 | ||
Telomere-based DNA damage responses: a new approach to melanoma | Q40521591 | ||
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation | Q40570996 | ||
The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways | Q40584861 | ||
Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms | Q40666765 | ||
Replicative senescence: an old lives' tale? | Q40968415 | ||
Escape from senescence in human diploid fibroblasts induced directly by mutant p53. | Q43459665 | ||
Molecular responses to photogenotoxic stress induced by the antibiotic lomefloxacin in human skin cells: from DNA damage to apoptosis. | Q44553535 | ||
Werner syndrome protein contains three structure-specific DNA binding domains | Q44611028 | ||
Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains | Q46330790 | ||
Kinetics of G-quartet-mediated tetramer formation | Q46658951 | ||
Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells. | Q52832311 | ||
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. | Q53422893 | ||
Checkpoints: How to activate p53 | Q56602132 | ||
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells | Q57250868 | ||
Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest | Q64048010 | ||
A role for both RB and p53 in the regulation of human cellular senescence | Q64378339 | ||
Erosion of the telomeric single-strand overhang at replicative senescence | Q73161631 | ||
Impaired nuclear localization of defective DNA helicases in Werner's syndrome | Q73552946 | ||
P433 | issue | 41 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 15073-15078 | |
P577 | publication date | 2006-10-02 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | A role for WRN in telomere-based DNA damage responses | |
P478 | volume | 103 |
Q35920445 | "...Rewritten in the skin": clues to skin biology and aging from inherited disease |
Q34690314 | Arsenic exposure, telomere length, and expression of telomere-related genes among Bangladeshi individuals |
Q38819605 | Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy |
Q34044618 | DNA damage to a single chromosome end delays anaphase onset |
Q42130385 | Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase |
Q37139643 | Enhanced cytotoxicity from deoxyguanosine-enriched T-oligo in prostate cancer cells. |
Q38757606 | FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway |
Q34977317 | From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging. |
Q36930862 | Helicases as prospective targets for anti-cancer therapy |
Q42105603 | Inhibition of melanoma angiogenesis by telomere homolog oligonucleotides |
Q37093551 | Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma |
Q35652897 | Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells |
Q58696640 | Oligonucleotides Targeting Telomeres and Telomerase in Cancer |
Q36915526 | Photoageing: mechanism, prevention and therapy |
Q87035464 | Photoaging |
Q37052183 | Photoprotection in human skin--a multifaceted SOS response |
Q28071818 | Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edge |
Q34989021 | Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment. |
Q37021646 | Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance |
Q24646853 | Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging |
Q47164570 | Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease |
Q37982375 | Telomerase-independent paths to immortality in predictable cancer subtypes |
Q33924555 | Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potential |
Q85360811 | Telomere-Based Protective Responses to DNA Damage |
Q37579017 | Telomere-mediated effects on melanogenesis and skin aging |
Q34194407 | Telomeres: structures in need of unwinding |
Q35749321 | Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells |
Q38348975 | Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage |
Q38288984 | Treating Cancer by Targeting Telomeres and Telomerase |
Q34726176 | WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer |
Q36798321 | Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases. |
Q38310060 | hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang |