Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma

scientific article published on May 2013

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.1047
P932PMC publication ID3742836
P698PubMed publication ID23800953
P5875ResearchGate publication ID242016928

P2093author name stringNeelu Puri
Ryan T Pitman
Luke Wojdyla
P2860cites workTankyrase, a poly(ADP-ribose) polymerase at human telomeresQ22008022
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresQ24291989
The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)Q24292328
c-Met is a potentially new therapeutic target for treatment of human melanomaQ40150516
Features that determine telomere homolog oligonucleotide-induced therapeutic DNA damage-like responses in cancer cellsQ40203284
Telomere-based DNA damage responses: a new approach to melanomaQ40521591
Expression and targeting of the apoptosis inhibitor, survivin, in human melanomaQ40912648
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.Q40926739
Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytesQ46718886
Concordant loss of melanoma differentiation antigens in synchronous and asynchronous melanoma metastases: implications for immunotherapy.Q52933889
Chemotherapy-induced apoptosis in melanoma cells is p53 dependent.Q54144441
Tankyrase promotes telomere elongation in human cellsQ56969704
DNA damage and melanogenesisQ60071776
TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblastsQ24301264
A human telomeric proteinQ24304466
Tankyrase inhibition stabilizes axin and antagonizes Wnt signallingQ24316697
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2Q24317670
Tumor antigens for cancer immunotherapy: therapeutic potential of xenogeneic DNA vaccinesQ24804837
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeresQ28119006
MITF: master regulator of melanocyte development and melanoma oncogeneQ28256859
Shelterin: the protein complex that shapes and safeguards human telomeresQ28272546
Telomeric localization of TRF2, a novel human telobox proteinQ28314941
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletionQ28507823
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2Q28609749
Protection of mammalian telomeresQ29618391
Stimulation of melanogenesis by DNA oligonucleotides: effect of size, sequence and 5' phosphorylationQ31871227
Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis.Q33356917
Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potentialQ33924555
Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcsQ34361226
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.Q34384662
Evidence that exposure of the telomere 3' overhang sequence induces senescenceQ34470102
T-oligos inhibit growth and induce apoptosis in human ovarian cancer cellsQ35048659
A role for WRN in telomere-based DNA damage responsesQ35062281
Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cellsQ35652897
Telomeric DNA induces apoptosis and senescence of human breast carcinoma cellsQ35749321
The telomeric PARP, tankyrases, as targets for cancer therapyQ36371977
Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21Q36612511
The universal character of the tumor-associated antigen survivinQ36975578
Telomerase inhibitors and 'T-oligo' as cancer therapeutics: contrasting molecular mechanisms of cytotoxicityQ37153582
p53 and E2f: partners in life and deathQ37602510
Novel anticancer therapeutics targeting telomeraseQ38030204
Tankyrase-targeted therapeutics: expanding opportunities in the PARP familyQ38063790
Induction of apoptosis by telomere 3' overhang-specific DNA.Q38288992
Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotidesQ38334543
Induction of a p95/Nbs1-mediated S phase checkpoint by telomere 3' overhang specific DNA.Q38358265
T-oligo induces apoptosis in advanced prostate cancer cellsQ39818861
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectDNA damageQ5205747
P304page(s)761-771
P577publication date2013-05-01
P1433published inOncotargetQ1573155
P1476titleMechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma
P478volume4

Reverse relations

cites work (P2860)
Q37437582Association of peripheral leukocyte telomere length and its variation with pancreatic cancer and colorectal cancer risk in Chinese population
Q38819605Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy
Q58579018Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivity
Q37045507High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness
Q36028285Low-level infrared laser modulates muscle repair and chromosome stabilization genes in myoblasts.
Q39095019Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides
Q39037222Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy
Q58696640Oligonucleotides Targeting Telomeres and Telomerase in Cancer
Q26744221Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
Q36756860SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically
Q89597527Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations
Q35121429T-oligo as an anticancer agent in colorectal cancer
Q38897533TAp63gamma is required for the late stages of myogenesis.
Q35784732Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?
Q26744808Telomere and Telomerase Therapeutics in Cancer
Q98158989Telomeres and telomerase in oncogenesis
Q38288984Treating Cancer by Targeting Telomeres and Telomerase
Q38310060hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang

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