Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα.

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Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. is …
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scholarly articleQ13442814

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P356DOI10.1084/JEM.20140979
P932PMC publication ID4322042
P698PubMed publication ID25601653
P5875ResearchGate publication ID271223618

P50authorBalthasar A HeestersQ83158491
P2093author name stringMichel J Massaad
Raif S Geha
Claire Galand
Oliver T Burton
Hamid Mattoo
John Manis
Juhan Yoon
Jana L Mooster
Haifa Jabara
Severine Le Bras
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A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiencyQ35231720
Inherited disorders of NF-kappaB-mediated immunity in man.Q35634019
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiencyQ36001303
Human disease resulting from gene mutations that interfere with appropriate nuclear factor-kappaB activationQ36015009
Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptorQ36184139
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A rapid screening method to detect autosomal-dominant ectodermal dysplasia with immune deficiency syndrome.Q50335729
Heterozygous N-terminal deletion of IkappaBalpha results in functional nuclear factor kappaB haploinsufficiency, ectodermal dysplasia, and immune deficiency.Q51733159
Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.Q52114309
A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".Q52583526
BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.Q53664665
Successful Allogeneic Hemopoietic Stem Cell Transplantation in a Child Who Had Anhidrotic Ectodermal Dysplasia With ImmunodeficiencyQ56940834
A hypermorphic IκBα mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiencyQ56941191
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectheterozygosityQ124059385
P304page(s)185-202
P577publication date2015-01-19
P1433published inJournal of Experimental MedicineQ3186912
P1476titleDefective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα
P478volume212