scholarly article | Q13442814 |
P50 | author | Shaomeng Wang | Q44006873 |
Haiying Sun | Q88797882 | ||
P2093 | author name string | Liu Liu | |
Chao-Yie Yang | |||
Jianfeng Lu | |||
P2860 | cites work | IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer | Q24292870 |
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Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs | Q27643305 | ||
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Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists | Q27655724 | ||
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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Q28117928 | ||
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IAP family proteins--suppressors of apoptosis | Q28297514 | ||
Improved protein-ligand docking using GOLD | Q29616787 | ||
IAP proteins: blocking the road to death's door | Q29619844 | ||
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias | Q31379722 | ||
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A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death | Q34346499 | ||
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A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment | Q36460712 | ||
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Design of small-molecule peptidic and nonpeptidic Smac mimetics | Q37176751 | ||
Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases | Q37185121 | ||
A potent bivalent Smac mimetic (SM-1200) achieving rapid, complete, and durable tumor regression in mice | Q37249659 | ||
IAP-targeted therapies for cancer | Q37302745 | ||
SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP. | Q37445045 | ||
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IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes. | Q52009124 | ||
Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy | Q79801646 | ||
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Structure-based design of potent, conformationally constrained Smac mimetics | Q95801450 | ||
P433 | issue | 4 | |
P921 | main subject | cell death | Q2383867 |
P304 | page(s) | 994-1002 | |
P577 | publication date | 2014-02-12 | |
P1433 | published in | ACS Chemical Biology | Q165583 |
P1476 | title | Potent and selective small-molecule inhibitors of cIAP1/2 proteins reveal that the binding of Smac mimetics to XIAP BIR3 is not required for their effective induction of cell death in tumor cells | |
P478 | volume | 9 |
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